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Antiretroviral Current Events | Antiretroviral News | 7

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Tuberculosis presents major challenges to HIV treatment in developing countries
Human immunodeficiency virus (HIV) care and treatment programs in resource-limited settings must aggressively address tuberculosis (TB) and the emerging multidrug-resistant TB epidemic to save patient lives and to curb the global TB burden, a major cause of death for persons with HIV.   view more (2008-07-23)

Many pregnant women avoid HIV screening in Africa
'Prevention is the best cure' is a common expression, but what happens if preventative measures are not used? A large proportion of pregnant Ugandan women are going out of their way not to be HIV tested, increasing the risk of mother-to-child transmission.   view more (2009-11-20)

Asthma risk increases in children treated for HIV
Children whose immune systems rebound after treatment with potent anti-viral drugs for HIV infection face an increased risk of developing asthma, said a federally funded consortium of researchers led by those from Baylor College of Medicine in a report that appears online in the Journal of Allergy and Clinical Immunology.    view more (2008-07-02)

HIV-infected infants respond poorly to childhood vaccination
It is known that HIV-infected children who do not receive appropriate antiretroviral drugs experience immune depression, and may become susceptible to infectious diseases that would otherwise be prevented by childhood immunization.   view more (2007-12-05)

Patients and their doctors have different perceptions about HIV and its treatment
According to results of a nation-wide study published in the latest issue of SAGE Publications' Journal of the International Association of Physicians in AIDS Care (JIAPAC), HIV positive patients and their doctors have very different views about the disease and how it's treated.   view more (2006-05-22)

If started early, HIV treatment reduces death rates toward background levels in African countries
Mortality rates of people starting HIV treatment in four African countries approach those of the general population over time, provided that treatment is started before the immune system has been severely damaged, according to research published this week in the open-access journal PLoS Medicine.    view more (2009-04-28)

HIV-1 spread through six transmission lines in the UK
Contrary to the prevailing belief that the HIV epidemic in the UK can be traced back to one source, a new study suggests that HIV spread via at least six independent virus introductions and subsequent transmission chains. The findings, published in the latest issue of the Proceedings of the National Academy of Sciences, also suggest that antiviral... view more... (2005-03-14)

Antiretroviral Therapy Effective In Reducing Mother-to-child HIV-1 Transmission When Started After Childbirth (p 1171)
Results of a study from Malawi in this week's issue of THE LANCET highlight how antiretroviral therapy targeted at babies soon after childbirth (because their mothers' HIV diagnosis was made around the time of delivery) is still effective in preventing vertical HIV-1 transmission from mothers to their children. Zidovudine and nevirapine have been... view more... (2003-10-08)

Viral genetic differences are possible key to HIV dementia
The study of 18 HIV-positive subjects shows that HIV in the brain and central nervous system is genetically different from HIV that lives in the blood and peripheral tissues.   view more (2006-07-26)

Science commentary stresses need for collaboration at local level in HIV-prevention studies
Clinical trials of drugs intended to prevent HIV infection in high-risk populations must be developed and carried out in close collaboration with the local communities and national governments of the countries in which they are conducted, according to 18 international leaders in HIV prevention writing in the current (Sept. 30, 2005) issue of... view more... (2005-10-03)

Study suggests life insurance should cover people treated for HIV (p 877)
Issue 13 September 2003 Embargoed 0001 h (London time) 12 September 2003. Authors of a Swiss study in this week's issue of THE LANCET highlight how people effectively treated for HIV-1 infection with highly active antiretroviral therapy (HAART) have similar or lower mortality rates than patients successfully treated for cancer-calling into... view more... (2003-09-10)

South Africa In Denial Over Number Of Deaths From HIV/AIDS
A recent study attempting to quantify misclassification of HIV/AIDS deaths concluded that for the year 2000-01, the number of deaths related to HIV/AIDS was likely to be almost three times as high as that published in the Government's statistical report compiled from death certificates. The study suggests that 80% of the excess deaths in men and... view more... (2005-02-09)

Immune exhaustion in HIV infection
As HIV disease progresses in a person infected with the HIV virus, a group of cells in the immune system, the CD8+ T lymphocytes, become "exhausted," losing many of their abilities to kill other cells infected by the virus.   view more (2008-05-06)

Concern over uncontrolled use of HIV drugs
Uncontrolled use of antiretroviral drugs in developing countries could accelerate HIV resistance, warn researchers in this week’s BMJ.   view more (2003-06-18)

AIDS inflicts specific pattern of brain damage, reveals UCLA/Pittsburgh imaging study
A new UCLA/University of Pittsburgh imaging study for the first time shows the selective pattern of destruction inflicted by AIDS on brain regions that control motor, language and sensory functions.   view more (2005-10-11)

DECREASE IN AIDS-RELATED ILLNESS IN EUROPE (p 291)
During 1996 and 1997, highly active antiretroviral therapy (HAART) was introduced to treat HIV-1-infected patients who had low CD4-cell counts. In this week's issue of THE LANCET, A Mocroft and colleagues report findings from the EuroSIDA study, which looked at the change in incidence of AIDS-defining illnesses (ADIs) since the introduction of... view more... (2000-07-19)

Study finds nontuberculous mycobacteria lung disease on the rise in the United States
Nontuberculous mycobacteria (NTM) are environmental organisms found in both water and soil that can cause severe pulmonary (lung) disease in humans. Pulmonary NTM is on the rise in the United States, according to a large study of people hospitalized with the condition.   view more (2009-09-25)

Malaria treatment efficacy compromised in certain HIV-positive patients
A weakened immune response resulting from HIV infection can lead to trouble when it comes to treating malaria.   view more (2006-09-08)

Climate change threats to HIV rates
Social factors, including economic pressures caused by climate change, could lead to an increase in HIV infection rates world-wide, warns a leading researcher from the University of New South Wales (UNSW).   view more (2008-04-30)

New hope for HIV sufferers as immunosuppressant delays AIDS onset
A drug that suppresses the immune system delays the onset of AIDS in patients with HIV, according to a study published this week in BMC Medicine. Prednisolone, taken without any antiviral therapy, postponed the loss of T-cells that leads to AIDS in 50% of HIV sufferers by between 2 and 10 years. HIV leads to a complex disorder that combines an... view more... (2004-04-30)
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