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Action needed to avoid HIV drug resistance in Africa
We should stop and think about the risks of resistance, and ways of minimising them, before increasing access to antiretroviral therapy in Africa, argue researchers in this week's BMJ.   view more (2004-01-29)

ADVERSE EFFECTS OF ANTIRETROVIRAL TREATMENT FOR HIV INFECTION (p1320)
It is well known that treatment of HIV-1 infection (that may lead to AIDS) has side effects, but there are few studies of how many people having treatment are affected by adverse reactions. In a study of 1160 people receiving antiretroviral treatment, published in The Lancet this week, Jacques... view more (2001-10-17)

EARLY ASSESSMENT PREDICTS LONG-TERM EFFICACY OF HIV-1 ANTIRETROVIRAL THERAPY (p 1760)
A study in this week's issue of THE LANCET highlights how very early (one week) assessment can reliably predict the long-term effectiveness of antiretroviral therapy for HIV-1. Early assessment of antiretroviral drug efficacy is important for the prevention of the emergence of drug-resistant virus... view more (2001-11-21)

LIPODYSTROPHY RISK FROM HIV-1 THERAPY (p 592)
The risk of lipodystrophy (abnormal fat distribution) in HIV-1 individuals undergoing antiretroviral therapy cannot be attributed to one antiretroviral agent, conclude authors of a study in this week's issue of THE LANCET. Lipodystrophy among HIV-1-infected patients receiving antiretroviral therapy... view more (2001-02-21)

Ethnic differences in response to HIV medicines
Researchers from the University of Massachusetts and the University of Pennsylvania have shown that race/ethnicity is a predictor of plasma lipids in patients with HIV-1 on HAART (highly active antiretroviral therapy).   view more (2006-01-24)

Successful Implementation Of Pilot Study For Hiv Antiretroviral Therapy In Uganda (p 34)
Authors of a study in this week's issue of THE LANCET report on the successful implementation of a UNAIDS/Uganda Health Ministry initiative to provide antiretroviral treatment to people with HIV/AIDS in Uganda. Little is known about how to implement complex HIV-1 treatment programmes in... view more (2002-07-03)

Certain HIV treatment less effective when used with anti-TB therapy
Patients receiving rifampicin-based anti-tuberculosis therapy are more likely to experience virological failure when starting nevirapine-based antiretroviral therapy, an HIV treatment that is widely used in developing countries because of lower cost, than when starting efavirenz-based... view more (2008-08-04)

Women with AIDS face cervical cancer threat
According to a report issued last week by UNAIDS, access to antiretroviral therapy is beginning to reduce AIDS mortality worldwide.   view more (2007-12-03)

Sustained Reduction In AIDS Since Introduction Of Highly Active Antiretroviral Therapy (p 22)
European research in this week's issue of THE LANCET highlights how the introduction of highly active antiretroviral therapy has had a sustained effect in reducing illness and death from HIV/AIDS over the past few years. Highly active antiretroviral therapy was introduced around 1996 and... view more (2003-07-02)

Human testis harbors HIV-1 in resident immune cells
Researchers have demonstrated HIV replication within resident immune cells of the testis, providing an explanation for the persistence of virus in semen even after effective highly active antiretroviral therapy.   view more (2006-11-27)

New Study Shows Benefit of Early Therapy in HIV-infected Infants
Antiretroviral therapy (ART) for infants born with HIV infection may be most effective when given in their first five months of life, according to a study published in the April 1 issue of The Journal of Infectious Diseases, now available online.   view more (2006-03-09)

HIV persists in the gut despite long-term HIV therapy
Even with effective anti-HIV therapies, doctors still have not been able to eradicate the virus from infected individuals who are receiving such treatments, largely because of the persistence of HIV in hideouts known as viral reservoirs.   view more (2008-02-14)

Increasing access to antiretroviral drugs would drastically cut AIDS deaths in South Africa
More that 1.2 million deaths could be prevented in South Africa over the next five years by accelerating efforts to provide access to antiretroviral therapy (ART), according to a study released online today by the Journal of Infectious Diseases.   view more (2008-03-27)

Long-term HIV treatment may reduce risk for atherosclerosis
Antiretroviral drugs for HIV do not increase the risk for coronary atherosclerosis, a central risk factor for heart disease, according to a study led by the University of Pittsburgh Graduate School of Public Health to be published in the Aug. 8 issue of the journal AIDS and available online today.   view more (2008-08-05)

New treatment model for HIV
Treatment of HIV patients must balance the need to suppress viral replication against the harmful side effects and significant cost to the patient of antiretroviral therapy.   view more (2007-07-13)

Study finds limited options for backup HIV treatment in some developing countries
Thai researchers have discovered that patients who fail treatment with a commonly used, inexpensive, first-line antiretroviral therapy (ART) are also usually resistant to other, similar drugs, leaving progressively fewer options for replacement therapies.   view more (2007-01-09)

Study finds limited options for backup HIV treatment in some developing countries
Thai researchers have discovered that patients who fail treatment with a commonly used, inexpensive, first-line antiretroviral therapy (ART) are also usually resistant to other, similar drugs, leaving progressively fewer options for replacement therapies.   view more (2007-01-09)

New Approaches To HIV Treatment In Less-developed Countries (pp 404, 410)
Two Viewpoint articles in this week's issue of THE LANCET highlight how the use of highly-active antiretroviral therapy (HAART) for HIV-1 treatment - currently only widely available in industrialised countries - could become accessible in less-developed settings. Both articles suggest new... view more (2001-08-01)

Anti-HIV Therapy Boosts Life Expectancy
The life expectancy for patients with human immunodeficiency virus (HIV) has increased by more than 13 years since the late 1990s thanks to advancements in antiretroviral therapy, according to researchers at the University of Alabama at Birmingham (UAB) and Simon Fraser University in Vancouver,... view more (2008-07-28)

Aids : Effectiveness of antiretroviral therapy demonstrated in Africa
Tritherapies using antiretroviral drugs have proved their worth in industrialized countries in the fight against Aids. However, in Sub-Saharan Africa, where 70 % of people infected with HIV live, access to such treatments is extremely limited. High cost, complicated procedures, combined with... view more (2002-06-27)

HIV drug resistance is increasing in the UK
The prevalence of transmitted HIV drug resistance in the United Kingdom is increasing, according to a study in this week's BMJ. This finding emphasises the urgent need for new approaches to encourage safer sexual behaviour. A total of 69 patients infected with HIV between June 1994 and August 2000... view more (2001-05-02)

Antiretroviral Therapy Around Childbirth Reduces Risk Of Mother-To-Child HIV-1 Transmission (pp 1168, 1178)
Antiretroviral therapy given to women before, during, and after childbirth could be beneficial in reducing mother-to-child HIV-1 transmission in the first few weeks after delivery, suggest authors of a study in this week's issue of THE LANCET. However, this short-term benefit could be compromised... view more (2002-04-04)

Timely Antiretroviral Therapy Essential For Best Prognosis In People With HIV-1 Infection (p 119)
Authors of an international study in this week's issue of THE LANCET highlight how timely treatment with highly-active antiretroviral therapy (HAART) can substantially improve the three-year prognosis for people with HIV-1 infection. HAART became widespread in more-developed countries in 1996.... view more (2002-07-10)

U of M study shows why treatment isn't effective for HIV
University of Minnesota researchers have answered a key question as to why antiretroviral therapy isn't effective in restoring immunity in HIV-infected patients.   view more (2008-08-06)

Important factors in compliance with HIV regimens identified; and more
Adherence to HIV medications is the greatest predictor of death. How well patients with HIV adhere to their regimens of highly active antiretroviral therapy (HAART) medication depends on a variety of factors, either positive or negative, many of which are common to patients around the world.   view more (2006-11-21)
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