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Antiretroviral Therapy Current Events | Antiretroviral Therapy News | 5

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Substantial Increase In Survival After Introduction Of Highly Active Antiretroviral Therapy For HIV-1 Infection (p 1267)
Research published in this week's issue of THE LANCET highlights the substantial increased survival for people with HIV-1 since the introduction of highly active antiretroviral therapy (HAART) in 1997. However the study also shows a shift in risk profiles compared with earlier data-people over 45 years no longer appear to have reduced survival... view more... (2003-10-15)

Injection of synthetic polymer may improve facial wasting syndrome associated with HIV
Facial injections of polylactic acid, a synthetic biodegradable polymer, may help improve the debilitating facial lipoatrophy (loss of fat in the face) associated with HIV infection and its treatment.   view more (2006-03-21)

International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), today announced that enrollment into a large international HIV/AIDS trial comparing continuous antiretroviral therapy with episodic drug treatment guided by levels of CD4+ cells has been stopped.   view more (2006-01-18)

HIV vaccine takes different tack to boosting immune response
esearchers at Baylor College of Medicine (BCM) in Houston have reason to believe their unorthodox vaccine could one day help to prevent or control HIV infection.   view more (2006-01-03)

Growth hormone reduces abdominal fat, cardiovascular risk in HIV patients on antiviral therapy
Low-dose growth hormone treatment reduced abdominal fat deposits and improved blood pressure and triglyceride levels in a group of patients with HIV lipodystrophy, a condition involving the redistribution of fat and other metabolic changes in patients receiving combination drug therapy for HIV infection.   view more (2008-08-04)

Aids In Thailand: First Step Towards Eradication Of Mother To Child Transmission?
Aids is one of the principal causes of infant mortality in many developing countries. Viral transmission takes place during pregnancy (in utero), at the moment of childbirth or even during breastfeeding. If no treatment is given, the virus is transmitted to about 35% of children of infected mothers. The use of a preventive treatment with... view more... (2004-07-01)

The Lancet Oncology and The Lancet Infectious Diseases
THE LANCET ONCOLOGY THE TRUE COST OF A NUCLEAR DETERRENT This month’s editorial covers the recent leaked report from the US Department of Health and Disease Control, showing the patterns of nuclear fallout across the US resulting from Cold War testing. The editorial discusses the impact of these data on cancer incidence and the worldwide... view more... (2002-03-27)

DECREASE IN AIDS-RELATED ILLNESS IN EUROPE (p 291)
During 1996 and 1997, highly active antiretroviral therapy (HAART) was introduced to treat HIV-1-infected patients who had low CD4-cell counts. In this week's issue of THE LANCET, A Mocroft and colleagues report findings from the EuroSIDA study, which looked at the change in incidence of AIDS-defining illnesses (ADIs) since the introduction of... view more... (2000-07-19)

Transmission of drug-resistant HIV-1
Drug-resistant forms of HIV can be spread between individuals who have not received anti-retroviral treatment.   view more (2009-03-30)

Researchers disprove 'fat redistribution syndrome' among men taking HIV drugs
There is no syndrome that causes increased belly fat and decreased facial and limb fat among HIV-positive men who take antiretroviral drugs.   view more (2005-10-14)

Resistant HIV quickly hides in infants' cells
New evidence shows that drug-resistant virus passed from mother-to-child can quickly establish itself in infants' CD4+ T cells where it can hide for years, likely limiting their options for future treatment.   view more (2007-05-01)

Hopkins AIDS experts issue warning about global efforts to provide drug therapies
Johns Hopkins infectious disease specialists who have spent more than two decades leading efforts to combat HIV and AIDS worldwide are warning that limited international relief supplies of antiretroviral therapies currently being distributed in Africa, Asia and the Caribbean will not get to those who can least afford to pay for them.   view more (2005-06-28)

Tuberculosis presents major challenges to HIV treatment in developing countries
Human immunodeficiency virus (HIV) care and treatment programs in resource-limited settings must aggressively address tuberculosis (TB) and the emerging multidrug-resistant TB epidemic to save patient lives and to curb the global TB burden, a major cause of death for persons with HIV.   view more (2008-07-23)

HIV-1 spread through six transmission lines in the UK
Contrary to the prevailing belief that the HIV epidemic in the UK can be traced back to one source, a new study suggests that HIV spread via at least six independent virus introductions and subsequent transmission chains. The findings, published in the latest issue of the Proceedings of the National Academy of Sciences, also suggest that antiviral... view more... (2005-03-14)

HIV patients have increased risk of pneumonia, death following surgery
HIV-infected patients undergoing surgical procedures may be more likely to develop pneumonia after surgery and to die within 12 months than those without HIV, according to a report in the December issue of Archives of Surgery, one of the JAMA/Archives journals.   view more (2006-12-19)

Clues to ensuring anti-HIV drugs are taken in Africa
HIV-infected patients in the African country of Tanzania were more likely to stop taking their medications and to fail treatment if they had to pay for the drugs themselves.   view more (2007-10-23)

Measles Vaccinations Need to be Repeated to Protect HIV-Infected Children
HIV-infected children may require repeat measles vaccination for protection, according to new research from the Johns Hopkins Bloomberg School of Public Health and other institutions.   view more (2007-07-18)

Pregnancy may slow -- not accelerate -- progression to AIDS
A new study may help put to rest fears that pregnancy accelerates progression to full-blown AIDS in women with HIV receiving antiretroviral therapy.   view more (2007-09-20)

New Therapeutic Vaccine for HIV/AIDS Eliminates Needles and Excessive Toxicity
DermaVir, a novel treatment for HIV/AIDS, offers a new option which complements and improves present drug therapies. The vaccine, applied topically to the skin, has demonstrated efficacy in boosting immune responses and controlling virus replication in chronically infected monkeys. This treatment possibly offers a new, non-invasive option for... view more... (2005-01-06)

Study examines cost-effectiveness of HIV monitoring strategy in countries with limited resources
In a computer-based model evaluating the benefits and costs of three types of HIV disease monitoring strategies, early initiation of antiretroviral therapy and monitoring using the CD4 count, a measure of immune system function, instead of based on symptoms appear to provide health benefits in low- and middle-income countries.   view more (2008-09-22)
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