Apoptosis Current Events | Apoptosis News
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Tumor cells evade death through autophagy
Autophagy is a cellular process that enables cells to turnover their contents, something that they do frequently. Autophagy is initiated in tumor cells by chemotherapy and radiation, but it is not known if this contributes to tumor cell death or helps tumor cells survive the anti-cancer therapy. view more (2007-01-19)
How do the choline compounds change when apoptosis occurs?
Apoptosis is a programmed, active, highly selective mechanism of cell death. Abnormal regulation of apoptosis can lead to disorders such as cancer. The field of apoptosis research has undergone an explosion of new knowledge over the past decade. view more (2008-09-24)
Cathepsin B increases apoptosis in fulminant hepatic failure
The traditional view is that hepatocyte necrosis is the main feature of fulminant hepatic failure, but increasing evidence implicates a dominant role for hepatocyte apoptosis in this pathogenesis. view more (2009-03-20)
Proteins are key to cell death in heart disease, stroke and degenerative conditions
Researchers at Yale School of Medicine have gained deeper understanding of two members of a family of proteins called caspases that play a key role in promoting apoptosis, a process in which the cell responds to external signals by essentially committing suicide. view more (2006-02-23)
Study by NTU professors provides important insight into apoptosis or programmed cell death
A study by Nanyang Technological University (NTU)'s Assistant Professor Li Hoi Yeung, Assistant Professor Koh Cheng Gee and their team have made an important contribution to the understanding of the process that cells go through when they die. view more (2009-07-14)
UC Davis researchers shed new light on how chemotherapy-induced leukemia develops
Topoisomerase II inhibitors are among the most successful chemotherapy drugs used to treat human cancer. view more (2005-11-16)
Key event in cell death occurs as single, quick event
Scientists at St. Jude Children's Research Hospital have demonstrated that a key event during apoptosis (cell suicide) occurs as a single, quick event, rather than as a step-by-step process. view more (2006-08-02)
Refusal of suicide order: Why tumor cells become resistant
Cells with irreparable DNA damage normally induce programmed cell death, or apoptosis. However, this mechanism often fails in tumor cells so that transformed cells are able to multiply and spread throughout the body. view more (2008-06-24)
Is Bcl-2 protein a major obstacle in treating colorectal carcinoma?
Apoptosis resistance has been shown to contribute to the development of different cancer entities, such as colorectal carcinoma (CRC). view more (2008-09-24)
First report that apoptotic and anti-angiogenic therapies work better together than alone
American researchers have found that giving a combination of imantanib (Glivec) and a drug that induces cell death (apoptosis) was better at inhibiting the growth of Ewing's sarcoma in mice than either therapy on its own. view more (2006-11-13)
New insight into the genetics of brain tumor formation
In a G&D paper published online ahead of its April 1 print publication date, Dr. William Kaelin (Dana Farber Cancer Institute) and colleagues identify a potential new neuronal tumor suppressor. view more (2008-03-18)
NEW TECHNIQUE SHOWS DEATH OF HEART CELLS IN HEART-ATTACK PATIENTS (P 209)
In this week's issue of THE LANCET, researchers from the Netherlands describe a new imaging technique capable of pinpointing areas of cell death in the hearts of patients who have had an acute myocardial infarction (heart attack). In acute myocardial infarction, the blood supply to part of the heart is cut off. When blood flow is restored, heart... view more... (2000-07-12)
A potent and selective anti-tumor agent on human gastric cancer
A research article to be published on June 21, 2009 in the World Journal of Gastroenterology addresses this question. view more (2009-06-29)
Large dose dexamethasone plays important roles in severe acute pancreatitis
Severe acute pancreatitis (SAP) is a fatal systemic disease featuring acute onset, serious conditions, high incidence of complications and 20 - 30% mortality, mainly due to multiple organ failure at its early stage. view more (2007-11-05)
Popular herbal supplement hinders the growth of pancreatic cancer cells
A new study from the University of Pittsburgh Cancer Institute suggests that a commonly used herbal supplement, triphala, has cancer-fighting properties that prevent or slow the growth of pancreatic cancer tumors implanted in mice. view more (2007-04-18)
Synthetic molecules hold promise for new family of anti-cancer drugs
Synthetic molecules designed by two Hebrew University of Jerusalem researchers have succeeded in reducing and even eliminating the growth of human malignant tissues in mice, while having no toxic effects on normal tissue. view more (2008-06-05)
What is the role of reactive oxygen species in ethanol-mediated cell death of polarized hepatic cells?
Liver disease that results as a consequence of alcohol abuse is a major medical problem worldwide. Ethanol consumption leads to a variety of liver alterations including the accumulation of fat, inflammation of the liver, as well as the presence of scar tissue. view more (2009-06-15)
Hepatitis C virus channels efforts into cell survival
Researchers at the University of Leeds have discovered a previously unknown mechanism that allows the hepatitis C virus (HCV) to remain in the body for decades. view more (2009-08-18)
Key study offers hope to patients with lung and joint disease
People who suffer from inflammatory conditions such as chronic diseases of the lung, joints and other organs could benefit from a new discovery by scientists at the University of Edinburgh. view more (2006-09-05)
Herbal tonic for radiotherapy
Antioxidant extracts of the leaves of the Gingko biloba tree may protect cells from radiation damage, according to a study published in the International Journal of Low Radiation. view more (2009-10-20)
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