Apoptosis Current Events | Apoptosis News | 3
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Protein That Promotes Cancer Cell Growth Identified
Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues. view more (2009-07-27)
Grape-seed extract kills laboratory leukemia cells, proving value of natural compounds
An extract from grape seeds forces laboratory leukemia cells to commit cell suicide, according to researchers from the University of Kentucky. They found that within 24 hours, 76 percent of leukemia cells had died after being exposed to the extract. view more (2009-01-05)
UGA study finds common component of fruits, vegetables kills prostate cancer cells
A new University of Georgia study finds that pectin, a type of fiber found in fruits and vegetables and used in making jams and other foods, kills prostate cancer cells. view more (2007-08-21)
K-State biologist hopes mosquito can break viral chain
Most people do their best to avoid mosquitoes. But this summer Rollie Clem will play the wary host to his own homegrown swarm of Aedes aegypti, the yellow fever mosquito. He's made a room ready for them, and even a menu. view more (2007-05-22)
Critical link in cell death pathway revealed
The role of a protein called XIAP in the regulation of cell death has been identified by Walter and Eliza Hall Institute researchers and has led them to recommend caution when drugs called IAP inhibitors are used to treat cancer patients with underlying liver conditions. view more (2009-07-23)
U. of Colorado team solves mystery of carcinogenic mothballs
Chemical compounds in household products like mothballs and air fresheners can cause cancer by blocking the normal process of "cell suicide" in living organisms, according to a new study spearheaded by the University of Colorado at Boulder. view more (2006-06-21)
Egg's Energy Stores Key to Preserving Fertility
An immature egg's internal nutrient supply is critical to its survival, an insight that offers a new route to understanding and treating infertility due to egg death. view more (2005-10-07)
By amplifying cell death signals, scientists make precancerous cells self-destruct
When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify the signals that tell these precancerous cells to... view more... (2008-08-18)
Relationship between environmental stress and cancer elucidated
One way environmental stress causes cancer is by reducing the activity level of an enzyme that causes cell death, researchers say. view more (2007-11-06)
Loss of caspase-8 makes neuroblastoma more aggressive
The caspase-8 gene plays a critical role in suppressing metastasis (spread) of neuroblastoma, and the expression of this gene is frequently absent in cancer cells that are aggressively metastasizing. view more (2006-01-06)
Suppression of FOXO1a gene might kill resistant ARMS tumors
The loss of function of a gene called FOXO1a plays an important role in the development of the most common cancer of soft tissues in children, and restoring the function of that gene in cancer cells suppresses that cancer. view more (2005-09-22)
Retinol for combating leukemia cells
Vitamin A, also known as retinol, is present in milk, liver, egg yolk, butter and other foodstuffs and as carotene in vegetables that have a yellow-orange colour, such as carrots and pumpkins. view more (2006-01-09)
FOXO factor promotes survival of oxygen-deprived cancer cells
Scientists report that an evolutionarily conserved transcription factor may have both positive and negative effects on the growth of tumors, depending on whether or not the tumor cells have enough oxygen. view more (2007-12-28)
Pretreating rogue cancer cells with aspirin cripples their resistance to targeted therapy
For years, we have heard about the health benefits of taking low doses of aspirin - preventing everything from Alzheimer's disease to heart attacks and stroke. view more (2005-12-13)
Blue light used to harden tooth fillings stunts tumor growth
A blue curing light used to harden dental fillings also may stunt tumor growth, Medical College of Georgia researchers say. view more (2008-06-25)
Agent protects cells from lethal effects of radiation even if given after exposure
No drugs exist to protect the public from the high levels of radiation that could be released by a "dirty" bomb or nuclear explosion. view more (2007-05-09)
How mitochondria get their membranes bent
Mitochondria are the powerhouses of cells. Underneath their smooth surface they harbor an elaborately folded inner membrane. It holds a multitude of bottleneck like invaginations, which expand into elongated cavities (cristae). view more (2009-06-25)
New therapeutic target for melanoma identified
A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research. view more (2009-04-16)
Finnish scientists discovered a new approach to treat virus-induced lymphomas
Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL). view more (2007-03-16)
MRC scientists advance understanding of cell death
Medical Research Council (MRC) scientists have made an important advance in understanding the biological processes involved when cells are prompted to die. view more (2009-08-14)
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