Apoptosis Current Events | Apoptosis News | 5
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Omega-3 fatty acids inhibit growth of liver cancer cells
Two new studies by a University of Pittsburgh research team suggest that omega-3 fatty acids-substances that are found in high concentrations in fish oils and certain seeds and nuts-significantly inhibit the growth of liver cancer cells. view more (2006-04-03)
Study outlines how stroke, head injury can increase risk of Alzheimer's disease
Researchers from the MassGeneral Institute for Neurodegenerative Disorders (MGH-MIND) have discovered how the death of brain cells caused by a stroke or head injury may cause generation of amyloid-beta protein - the key component of senile plaques seen in the brains of patients with Alzheimer's disease. view more (2007-06-07)
Synthetic molecule causes cancer cells to self-destruct
Scientists have found a way to trick cancer cells into committing suicide. The novel technique potentially offers an effective method of providing personalized anti-cancer therapy. view more (2006-08-28)
Understanding of cell protection mechanism points to therapies to prevent heart attacks and strokes
An understanding of how two genes cooperate to protect aortic muscle cells points to new therapies to treat arteriosclerosis, the major cause of heart attack and stroke, a study by Queen's University researchers concludes. view more (2006-07-20)
A potential therapeutic strategy for hepatic failure
Fulminant hepatic failure is a serious clinical disease and may threaten the life of patients. However, because of the damage of mass liver cells, the organ function is often irreversible due to the liver cell degeneration, swelling, or apoptosis. Thus, to supply new sources of functional liver cells is a valuable choice for these patients. view more (2009-03-31)
Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
A new study conducted by researchers from the University of Verona and the Institute G. Gaslini in Genova, Italy, confirms the pivotal role played by Cytomegalovirus infection in the pathogenesis of atherosclerosis. view more (2007-05-30)
NYU researchers demonstrate activity of mebendazole in metastatic melanoma
Researchers at the NYU Cancer Institute and the Ronald O. Perelman Department of Dermatology have identified mebendazole, a drug used globally to treat parasitic infections, as a novel investigational agent for the treatment of chemotherapy-resistant malignant melanoma. view more (2008-08-07)
Potential New Therapeutic Molecular Target to Fight Cancer
Researchers at the Virginia Commonwealth University Massey Cancer Center have identified the enzyme sphingosine kinase 2 as a possible new therapeutic target to improve the efficacy of chemotherapy for colon and breast cancer. view more (2007-11-02)
Major discovery raises prospect of better patient care by improving platelet life span
The research team led by Drs Benjamin Kile and David Huang has discovered that platelet life span is controlled by two key molecules. The discovery raises the prospect of developing a new drug to prolong the life span of platelets stored in blood banks, effectively increasing the availability of this life-saving blood product. view more (2007-03-23)
Study reveals a key to blood vessel growth and possible drug target
Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels. The finding not only offers an important insight into the development of the vascular system during embryonic development but suggests a potential target for inhibiting the blood vessels that fuel cancers, diabetic eye complications and... view more... (2007-10-15)
Dominant cholesterol-metabolism ideas challenged by new research
A team of researchers investigating cholesterol and lipid transport has performed experiments that cast serious doubt on the dominant hypothesis of how the body rids its cells of "bad" cholesterol (LDL) and increases "good" cholesterol (HDL). view more (2007-08-16)
ESC Congress 2004: PERTINENT - PERindopril - Thrombosis, InflammatioN, Endothelial dysfunction and Neurohormonal activation Trial
A Sub-Study of the EUROPA Study Evaluation of the Effect of Perindopril on Endothelial Function view more (2004-08-31)
Life and death in the living brain
Like clockwork, brain regions in many songbird species expand and shrink seasonally in response to hormones. Now, for the first time, University of Washington neurobiologists have interrupted this natural "annual remodeling" of the brain and have shown that there is a direct link between the death of old neurons and their replacement by... view more... (2009-08-11)
Molecule targets and kills tumor cells, starves blood supply
A man-made chemical compound called ARC causes tumor cells to die but leaves normal cells unharmed. view more (2006-03-16)
Genes that control cell death fingered in age-related hearing loss
Several genes that play a role in how our body's cells normally auto-destruct may play a role in age-related hearing loss, according to research published online in the journal Apoptosis - a journal devoted to the topic of cell suicide, or programmed cell death. view more (2008-10-17)
Targeting leukemic stem cells by Bcl-2 inhibition
Researchers at The University of Texas M. D. Anderson Cancer Center have found, in laboratory studies, that the experimental drug ABT-737 which has shown promise in some cancers, can destroy acute myeloid leukemia (AML) blast, progenitor and even stem cells that are often resistant to standard chemotherapy treatment. view more (2006-11-20)
Bio-engineering of blood vessels
Blood vessel prostheses work best when the biochemical and mechanical properties match reality as much as possible and when they are made of biodegradable material. To this end tissue technologists grow natural vascular wall cells, endothelial cells, in a biodegradable tube made of collagen. According to Professor Istv'¡n Vermes tissue... view more... (2002-04-16)
Photonic crystal biosensors detect protein-DNA interactions
Scientists at the University of Illinois have developed a new class of disposable, microplate-based optical biosensors capable of detecting protein-DNA interactions. Based on the properties of photonic crystals, the biosensors are suitable for the rapid identification of inhibitors of protein-nucleic acid and protein-protein interactions. view more (2008-09-24)
St. Jude announces breakthrough in eye cancer treatment
Scientists at St. Jude Children's Research Hospital have demonstrated in a mouse model a new, locally applied treatment for the eye cancer retinoblastoma that not only greatly reduces the size of the tumor, but does so without causing the side effects common with standard chemotherapy. view more (2006-11-02)
Treatments have same target, different responses for lung cancer patients with genetic mutation
The gene mutation that identifies the lung cancer patients most likely to respond to the drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux). view more (2005-08-17)
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