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CSHL-led team identifies key decision-point at which cells with broken DNA repair themselves or die
When cells undergo potentially catastrophic damage, for example as a result of exposure to ionizing radiation, they must make a decision: either to fix the damage or program themselves for death, a process called apoptosis. view more (2009-04-13)
Can EP4 agonist alleviate gastric lesions?
Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding. view more (2009-11-18)
Scientists track impact of DNA damage in the developing brain
Switching off a key DNA repair system in the developing nervous system is linked to smaller brain size as well as problems in brain structures vital to movement, memory and emotion. view more (2009-07-28)
Nutrition and heredity are genetically linked
A challenging goal in biology is to understand how the principal cellular functions are integrated so that cells achieve viability and optimal fitness under a wide range of nutritional conditions. view more (2007-05-17)
Estrogen can reduce stroke damage by inactivating protein
Estrogen can halt stroke damage by inactivating a tumor-suppressing protein known to prevent many cancers, Medical College of Georgia researchers say. view more (2009-07-17)
Defeating nicotine's double role in lung cancer
A lung cancer treatment that inhibits nicotine receptors was shown to double survival time in mice, according to Italian researchers. view more (2009-06-09)
Researchers Discover New Factor in Nerve Regeneration
Researchers in Oxford University's Department of Human Anatomy have identified a factor involved in the regeneration of neurons in the central nervous system. The discovery and use of this factor could provide the basis for a reparative treatment for both brain and spinal cord injuries. Unlike lower vertebrates, mammals have lost the ability to... view more... (2003-04-07)
Cancer related gene p53 not regulated as indicated by previous tissue culture research
The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. view more (2005-06-28)
Hebrew University researchers neutralize tumor growth in embryonic stem cell therapy
Researchers at the Hebrew University of Jerusalem have discovered a method to potentially eliminate the tumor-risk factor in utilizing human embryonic stem cells. view more (2009-05-07)
Honey-bee products in cancer treatment and prevention
Natural honey-bee products such as propolis, royal jelly, caffeic acid, honey and venom may have applications in cancer treatment and prevention, say Croatian researchers in Journal of the Science of Food and Agriculture this month. view more (2004-12-02)
Studies shed new light on why exercise can protect against skin and bowel cancers
Two studies have shown that exercise can protect against skin and bowel cancer, and they have identified new mechanisms that could be responsible for this effect. view more (2006-05-15)
Aetiology of congenital heart disease explained
Researchers at Karolinska Institutet have identified the mechanisms behind the serious, congenital heart condition that can sometimes develop in children of women with a rheumatic disease. view more (2005-02-07)
New clues about mitochondrial 'growth spurts'
Mitochondria are restless, continually merging and splitting. But contrary to conventional wisdom, the size of these organelles depends on more than fusion and fission, as Berman et al. show. Mitochondrial growth and degradation are also part of the equation. view more (2009-03-02)
When what we eat can protect our health
Key research participants include Professor Gordon McVie, from The Cancer Research Campaign who will speak on 'cancer biology - environmental aspects of causes and prevention' and Professor Frans Kok from Wageningen Agricultural University, Holland who will discuss how we substantiate the public health impact of fruit and vegetables. view more (1999-09-04)
Metals could forge new cancer drug
Drugs made using unusual metals could form an effective treatment against colon and ovarian cancer, including cancerous cells that have developed immunity to other drugs, according to research at the University of Warwick and the University of Leeds. view more (2009-10-19)
Inhibitor of novel cancer target, LPAAT-beta, demonstrates selective anti-cancer effects in animal cancer models
Frankfurt, Germany: In a plenary session at the Symposium on Molecular Targets and Cancer Therapeutics, Dr Jack W. Singer, M.D. and Research Program Chairman of Cell Therapeutics, Inc. (CTI) today (Thursday 21 November) presented data from preclinical studies on a novel cancer target LPAAT-beta[1] in cultured cells and in preliminary animal... view more... (2002-11-17)
PPAR-g agonists have potential therapeutic role in gastric carcinoma?
Recently, the potential of PPAR-γ as a target for the prevention and treatment of cancer has been widely studied. view more (2009-08-27)
Nixing immaturity in red blood cells
A process of self-digestion called autophagy prompts the maturation of red blood cells. Without a protein called Nix, the cells would not effectively rid themselves of organelles called mitochondria and consequently become short-lived, leading to anemia, said researchers at Baylor College of Medicine in Houston in a report that appears online... view more... (2008-05-05)
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