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Key study offers hope to patients with lung and joint disease
People who suffer from inflammatory conditions such as chronic diseases of the lung, joints and other organs could benefit from a new discovery by scientists at the University of Edinburgh. view more (2006-09-05)
Genetics plays a role in the side effects experienced by people taking painkillers
A study published in the January issue of the American Gastroenterological Association (AGA) journal Gastroenterology found a difference in how people responded to popular painkillers and that up to 30 percent of this variability can be attributed to an individual's genetic make-up. view more (2006-01-05)
Groundbreaking study on complex movements of enzymes
A groundbreaking study has revealed in great detail how enzymes in the cell cooperate to make fat. These enzymes are integrated into a single molecular complex known as fatty acid synthase. This complex is regarded as a potential target for developing new anti-obesity and anti-cancer drugs. view more (2009-02-12)
New anthrax inhibitor could combat antibiotic-resistant strains
In a new approach to treating anthrax exposure, a team of scientists has created an inhibitor designed to tackle the growing threat of antibiotic-resistant strains. view more (2006-08-29)
Effectiveness of first renin inhibitor drug for treating hypertension is limited
Hypertension is a serious condition affecting millions. Currently there are seven classes of drugs used to reduce blood pressure. view more (2007-05-10)
Drug helps cognitive function in brain tumor patients after radiation
A drug that is marketed to treat Alzheimer's disease also improves cognitive function, mood and quality of life in brain tumor patients following radiation therapy. view more (2006-03-20)
New mechanism identified for resistance to targeted lung cancer drugs
An international research team, led by investigators from the Massachusetts General Hospital (MGH) Cancer Center and Dana-Farber Cancer Institute (DFCI), has found a new way that some lung tumors become resistant to treatment with targeted therapy drugs like Iressa and Tarceva. view more (2007-04-27)
Topical erectile dysfunction therapy shows promise
An innovative drug-delivery system - nanoparticles encapsulating nitric oxide or prescription drugs - shows promise for topical treatment of erectile dysfunction (ED), according to a new study by scientists at Albert Einstein College of Medicine of Yeshiva University. view more (2009-09-21)
Inhibitor of novel cancer target, LPAAT-beta, demonstrates selective anti-cancer effects in animal cancer models
Frankfurt, Germany: In a plenary session at the Symposium on Molecular Targets and Cancer Therapeutics, Dr Jack W. Singer, M.D. and Research Program Chairman of Cell Therapeutics, Inc. (CTI) today (Thursday 21 November) presented data from preclinical studies on a novel cancer target LPAAT-beta[1] in cultured cells and in preliminary animal... view more... (2002-11-17)
Potential pharmaceutical drugs in the field of cancer
Raquel Villar Becares, in her PhD thesis at the Public University of Navarre, has developed new derivatives of benzo[b]tiophene 1,1-dioxide that enable their application in the pharmaceutical field. view more (2005-12-23)
Test reveals effectiveness of potential Huntington's disease drugs
A test using cultured cells provides an effective way to screen drugs against Huntington's disease and shows that two compounds - memantine and riluzole - are most effective at keeping cells alive under conditions that mimic the disorder, UT Southwestern Medical Center researchers report. view more (2006-10-30)
Test reveals effectiveness of potential Huntington's disease drugs
A test using cultured cells provides an effective way to screen drugs against Huntington's disease and shows that two compounds-memantine and riluzole - are most effective at keeping cells alive under conditions that mimic the disorder, UT Southwestern Medical Center researchers report. view more (2006-10-31)
New compound unusually potent at blocking brain cancer growth
By determining how a class of compounds blocks signaling in cells, UCSF scientists have identified what is perhaps the most potent drug candidate yet against a highly lethal kind of brain tumor. view more (2006-05-16)
Research promising for cystic fibrosis
New U of T research holds promise for developing innovative therapies against cystic fibrosis and may also serve as a model for future therapies against the HIV virus. view more (2008-03-19)
Scientists Determine Drug Target for the Most Potent Botulinum Neurotoxin
Botulinum neurotoxin -- responsible for the deadly food poisoning disease botulism and for the beneficial effects of smoothing out facial wrinkles - can also be used as a dreaded biological weapon. view more (2008-04-30)
A longer lasting tumor blocker
On the heels of dismaying reports that a promising antitumor drug could, in theory, shorten patients' long-term survival, comes a promising study by a Japanese team of researchers that suggests a potentially better option. view more (2009-04-28)
Licorice compound offers new cancer prevention strategy
A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report. view more (2009-03-24)
Two-drug treatment may block source of asthma and chronic bronchitis
Current treatments for asthma and chronic bronchitis aren't able to address the ultimate source of the problem-they can only alleviate symptoms. view more (2006-02-02)
Avoiding heart failure after cancer drugs - new hope for early diagnosis, treatment and prevention of cardiotoxicity
New hope that heart failure - a potentially fatal side effect of some types of cancer drugs - can be diagnosed early and successfully treated or even prevented, is reported today (Thursday 2 May) in Annals of Oncology, journal of the European Society for Medical Oncology. A team from the University of Milan* has found evidence that elevated blood... view more... (2002-04-28)
LIPODYSTROPHY RISK FROM HIV-1 THERAPY (p 592)
The risk of lipodystrophy (abnormal fat distribution) in HIV-1 individuals undergoing antiretroviral therapy cannot be attributed to one antiretroviral agent, conclude authors of a study in this week's issue of THE LANCET. Lipodystrophy among HIV-1-infected patients receiving antiretroviral therapy was formally described as a clinical entity in... view more... (2001-02-21)
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