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Nearly 40 percent of GERD patients taking PPIs experience recurring symptoms
Despite daily use of doctor-recommended proton pump inhibitors (PPIs) to control gastroesophageal reflux disease (GERD) symptoms, nearly 40 percent of patients who take them continue to experience breakthrough, which is a return of GERD symptoms, such as acid regurgitation and heartburn. view more (2008-05-16)
No-entry zones for AIDS virus
The AIDS virus inserts its genetic material into the genome of the infected cell. Scientists of the German Cancer Research Center have now shown for the first time that the virus almost entirely spares particular sites in the human genetic material in this process. This finding may be useful for developing new, specific AIDS drugs. view more (2009-11-13)
New understanding of COX-1 and COX-2 enzymes could lead to revised classification of pain meds, Queen's study shows
COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more complex manner than was previously understood, a Queen's University study has found. view more (2006-05-30)
Scientists Show Drug Can Counteract Muscular Dystrophy in Mice
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other institutions have demonstrated for the first time that a single drug can rebuild damaged muscle in two strains of mice that develop diseases comparable to two human forms of muscular dystrophy. view more (2006-10-05)
A new chemotherapeutic target for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation. view more (2007-10-25)
Painkillers may threaten power of vaccines
With flu-shot season in full swing and widespread anticipation of the HPV vaccine to prevent cervical cancer, a new University of Rochester study suggests that using common painkillers around the time of vaccination might not be a good idea. view more (2006-11-29)
Chemical genomic screening identifies novel therapeutic strategies for cancer
A sophisticated new chemical genetic screening strategy that serves as a tool for identifying anticancer compounds may significantly enhance the drug discovery process. view more (2006-09-29)
Scripps research team defines new painkilling chemical pathway
Marijuana kills pain by activating a set of proteins known as cannabinoid receptors, which can also regulate appetite, inflammation, and memory. view more (2008-11-24)
Therapeutic effect of imatinib improved with addition of chloroquine
The therapeutic effects of the blockbuster leukemia drug imatinib may be enhanced when given along with a drug that inhibits a cell process called autophagy, researchers from the Kimmel Cancer Center at Jefferson reported in the Journal of Clinical Investigation. view more (2009-04-14)
Conaway Lab uncovers function of potential cancer-causing gene product
The Stowers Institute's Conaway Lab has uncovered a previously unknown function of a gene product called Amplified in Liver Cancer 1 (Alc1), which may play a role in the onset of cancer. view more (2009-08-10)
Combining targeted therapy drugs may treat previously resistant tumors
A team of cancer researchers from several Boston academic medical centers has discovered a potential treatment for a group of tumors that have resisted previous targeted therapy approaches. view more (2008-12-01)
Universitat Autonoma de Barcelona researchers first to clone mice in Spain
Researchers at the Department of Cell Biology, Physiology and Immunology at Universitat Autònoma de Barcelona (UAB) are the first to have cloned mice in Spain. Cloe, Cleo and Clona are three female brown-coloured mice and were born respectively on 12 May, 3 June and 10 June. view more (2009-06-12)
Sidestepping cancer's chaperone
Cancerous tumors are wildly unfavorable environments. Struggling for oxygen and nutrients while being bombarded by the body's defense systems, tumor cells in fact require sophisticated adaptations to survive and grow. view more (2007-10-22)
Unlocking the body's defenses against cancer
Scientists have discovered a way of allowing healthy cells to take charge of cancerous cells and stop them developing into tumours in what could provide a new approach to treating early-stage cancers. view more (2009-08-26)
Comparison of venlafaxine and SSRIs in the treatment of depression
There are numerous antidepressant medications currently on the market, but sadly, many patients still experience the debilitating symptoms of depression even with treatment. view more (2008-02-22)
Casting a wide net to fight coronaviruses
Coronaviruses-the family of viruses that causes the common cold-gained widespread recognition when the deadly severe acute respiratory syndrome, familiarly known as SARS, killed at least 800 people in 2003. view more (2005-09-06)
Resetting epigenetic code could aid lupus patients
Researchers at Wake Forest University School of Medicine and the University of Virginia hope to reset part of the "epigenetic code" in lupus patients and thus improve treatment. view more (2005-11-08)
Scientists discover basic defect in cystic fibrosis airway glands
Scientists at Stanford University have determined that the buildup of sticky mucus found in cystic fibrosis is caused by a loss in the epithelial cell's ability to secrete fluid. view more (2006-03-20)
Blood pressure drug shows potential as lung cancer treatment
A hormone that is important in the control of blood pressure also shrinks lung cancer tumors in mice, suggesting a new way to prevent or treat the deadly cancer, according to scientists at Wake Forest University School of Medicine. view more (2007-03-15)
Metal-containing compounds show promise as HIV weapon
A molecule consisting of two "cages" of metallic atoms bound to carbon has shown great promise in preliminary tests of becoming a new weapon in the anti-HIV arsenal, researchers at UT Southwestern Medical Center report. view more (2005-11-01)
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