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Treatment extends survival in mouse model of spinal muscular atrophy
Drug therapy can extend survival and improve movement in a mouse model of spinal muscular atrophy (SMA), new research shows. The study, carried out at the NIH's National Institute of Neurological Disorders and Stroke (NINDS), suggests that similar drugs might one day be useful for treating human SMA.   view more (2007-02-23)

Myostatin inhibitors may improve recovery of wartime limb injuries
Inhibiting a growth factor that keeps muscles from getting too big may optimize recovery of injured soldiers, researchers say.   view more (2008-07-09)

Erectile dysfunction drugs allowed more chemotherapy to reach brain tumors in laboratory study
In a study using laboratory animals, researchers found that medications commonly prescribed for erectile dysfunction opened a mechanism called the blood-brain tumor barrier and increased delivery of cancer-fighting drugs to malignant brain tumors.   view more (2008-07-29)

Penn researchers discover key to how SARS virus infects cells
Researchers from the University of Pennsylvania School of Medicine have found that inhibitors of an enzyme called cathepsin L prevent the SARS (severe acute respiratory syndrome) virus from entering target cells. SARS is caused by an emergent coronavirus.   view more (2005-08-02)

New research shows no link between aromatase inhibitors and cardiovascular problems
New evidence has emerged that, contrary to some current fears, aromatase inhibitors (AIs) are not associated with an increased risk of heart problems in women who take them to prevent their breast cancer recurring.   view more (2008-04-17)

Dementia drugs may put some patients at risk, Queen's study shows
Side effects associated with several commonly-prescribed dementia drugs may be putting elderly Canadians at risk, says Queen's University Geriatrics professor Sudeep Gill.   view more (2009-05-28)

FDA causes unnecessary scare about common painkillers
The U.S. Food and Drug Administration (FDA) has caused an unnecessary scare about some pain relievers by adding a warning to drugs that are safe.   view more (2007-04-25)

Possible New Cure for Psoriasis
Cell biologists of the University of Bonn, in cooperation with the University of Leeds (U.K.) and industry may have discovered a new effective therapy for psoriasis: a specific group of what are known as metalloproteinase inhibitors can normalise the increased tendency of epidermis cells (keratinocytes) to divide, which is the cause of this... view more... (2004-08-16)

Transplants In HIV Patients Should Proceed But Drug Interactions Can Be Concern, Concludes Research At International Congress Of The Transplantation Society
While historically surgeons have been reluctant to transplant patients with the human immunodeficiency virus (HIV), in recent years, some centers have begun to accept patients with well-controlled HIV as candidates for liver or kidney transplantation. Based on results of three studies from the United States and one from France, which collectively... view more... (2002-08-20)

Drug shown to provide much needed alternative therapy for chronic shoulder pain
After the rise in safety concerns surrounding Vioxx and other Cox-2 inhibitors, people suffering from chronic shoulder pain were left with just two therapy options at opposite extremes-take Advil, or have surgery.   view more (2006-03-27)

Women with breast cancer do not get potentially life-saving information, survey reveals
New published data from a large pan-European survey indicate that the majority of postmenopausal women with early breast cancer taking post-surgical endocrine therapy are not involved in making key decisions about their treatment, nor are they given sufficient information to make informed treatment choices that could affect their long-term outcome.   view more (2007-05-24)

New cancer drug hope
Scientists helping to develop the next generation of cancer-beating drugs say they have had a major breakthrough with their latest results.   view more (2006-10-27)

Enzyme may hold key to new treatment of diabetic kidney disease
Northwestern University Feinberg School of Medicine researchers have found that an enzyme called ACE2 may hold the potential to treat diabetic kidney disease, the most common form of kidney disease.   view more (2006-11-08)

Is esomeprazole the best choice for reflux esophagitis patients?
In patients with gastroesophageal reflux disease (GERD), esomeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors( PPIs ).   view more (2009-03-03)

Researchers restore missing protein in rare genetic brain disorder
UCSF researchers have successfully used protease inhibitors to restore to normal levels a key protein involved in early brain development. Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, which is characterized by brain malformations, seizures, severe mental retardation and very early death in human... view more... (2009-09-08)

Novel strategy under study for aggressive leukemia
A novel strategy to hopefully beat into oblivion one of the most aggressive forms of acute myelogenous leukemia combines the strengths of some of the newest leukemia agents, researchers say.   view more (2007-09-25)

First high-res 3D structures of mammalian HSP90 protein solved
Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers.   view more (2007-10-15)

Study provides clues to prevent spread of ovarian cancer
A drug that blocks production of an enzyme that enables ovarian cancer to gain a foothold in a new site can slow the spread of the disease and prolong survival in mice, according to a study by researchers from the University of Chicago Medical Center, but only if the drug is given early in the disease process.   view more (2008-03-14)

Study suggests brain tumors need treatment with multiple 'targeted' drugs
Researchers at Dana-Farber Cancer Institute have shown that several, rather than just one, cell-growth switches are simultaneously overactive in many brain tumors and other solid tumors, explaining why treatment with just a single "targeted" switch-blocking drug often yields disappointing results.   view more (2007-09-14)

Pest control research leads to pain control discovery
A newly discovered enzyme inhibitor, identified by researchers originally looking for biological pest controls, may lead to pain relief for sufferers of arthritis and other inflammatory diseases.   view more (2006-08-29)
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