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Watery pools in bone marrow key to psoriatic arthritic damage
Researchers have learned more about how a leading drug prevents certain types of arthritis from eating away at bone, according to a study published in the March edition of the Annals of the Rheumatic Diseases. view more (2008-03-04)
Wasabi's kick linked to single pain receptor
A single pain receptor is responsible for the kick delivered by garlic and mustard oil, which is the active ingredient in mustard and in the pungent green sushi condiment known as wasabi, according to a Yale School of Medicine study published this week in Cell. view more (2006-03-27)
Arthritis drug might prove effective in fighting the flu, study suggests
Researchers at the University of Maryland School of Medicine have found that an approved drug for treating rheumatoid arthritis reduces severe illness and death in mice exposed to the Influenza A virus. view more (2009-05-27)
Resolvins have the potential to resolve periodontal inflammation and restore tissue health
Periodontal (gum) disease is a chronic inflammation initiated by bacteria that affect the gums and bone supporting the teeth, and may eventually result in tissue and tooth loss. view more (2009-04-06)
Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage
Early-stage research has found that a new gene therapy can nearly eliminate arthritis pain, and significantly reduce long-term damage to the affected joints, according to a study published today in the journal Arthritis and Rheumatism. view more (2007-05-29)
IT takes steps to help people with joint disorders
A new generation of devices to help people with joint disorders walk with ease and comfort are becoming a reality thanks to the work of GAIT, which is creating the world's first 'intelligent' mechanical devices to support knee and ankle joints. view more (2004-12-10)
MIT: New tissue scaffold regrows cartilage and bone
MIT engineers and colleagues have built a new tissue scaffold that can stimulate bone and cartilage growth when transplanted into the knees and other joints. view more (2009-05-12)
'Mint' pain killer takes leaf out of ancient medical texts
A new synthetic treatment inspired by ancient Greek and Chinese remedies could offer pain relief to millions of patients with arthritis and nerve damage, a new University of Edinburgh study suggests. view more (2006-08-22)
What's been causing your knee to ache? Smurfs!
A new clinical trial seeks to predict who is most likely to experience osteoarthritis, and to test whether an experimental treatment can prevent it altogether. Physicians are setting their sights on people who sustain a knee injury, seeking to understand why nearly half of them will later go on to develop osteoarthritis, a debilitating condition... view more... (2007-10-22)
Guidance of Primordial Germ Cell Migration by the Chemokine SDF-1
Identification of the molecular cues governing cell migration is of major importance for the understanding of tissue and organ development and for therapy in cases of diseases resulting from aberrant cell movement. Primordial Germ Cell (PGC) migration is a useful model for studying directional cell movement. During embryonic development, PGCs have... view more... (2002-11-27)
Nearly half of U.S. adults will develop painful knee osteoarthritis by age 85: study
Almost half of all U.S. adults and nearly two-thirds of obese adults will develop painful osteoarthritis of the knee by age 85, a study based at the University of North Carolina at Chapel Hill suggests. view more (2008-09-03)
Loss of sleep, even for a single night, increases inflammation in the body
Loss of sleep, even for a few short hours during the night, can prompt one's immune system to turn against healthy tissue and organs. view more (2008-09-03)
Microbes start immune response by sneaking inside cells
Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought. In a new paper, University of Michigan scientists describe their findings that bacteria can barge inside these guard cells and independently initiate... view more... (2007-04-16)
Major Training Investment In Tomorrow's Experts In Bone And Joint Disorders
An outstanding opportunity has been created for students interested in leading edge biosciences related to bone, joint and rheumatic disorders. The Oliver Bird rheumatism programme is awarding a total of £3,000,000 to five UK academic institutions to establish a cohort of 25 highly talented young scientists who will receive comprehensive... view more... (2003-10-13)
Lupus more severe in patients with Southern European ancestry
ystemic lupus erythematosus (SLE) patients with a higher percentage of ancestry from southern Europe have more severe disease manifestations, according to new research presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France. view more (2008-06-12)
Study reveals 2 genes linked to disabling arthritis
An international team of researchers led by a Fred Hutchinson Cancer Research Center geneticist has discovered two genes linked to a disabling form of arthritis called ankylosing spondylitis, a painful and progressive disease in which some or all of the spine's vertebrae fuse together. view more (2007-10-22)
Finding paves way for better treatment of autoimmune disease
A signaling molecule with an affinity for alcohol has yielded a rapid, inexpensive way to make large numbers of immune cells that work like beat cops to keep misguided cells from attacking the body. view more (2006-08-10)
Osteoarthritis risk linked to finger length ratio
People whose index finger is shorter than their ring finger are at higher risk of osteoarthritis, a new University of Nottingham study has found. view more (2008-01-07)
Corticosteroid therapy may be associated with irregular heartbeat
High doses of medications known as corticosteroids may be linked to an increased risk for atrial fibrillation, a heart rhythm disorder characterized by an irregular heartbeat. view more (2006-05-09)
New Test for Joint Infection Could Spare Some Patients an Unnecessary Procedure
A potential diagnostic test that could help surgeons confirm or rule out the presence of infection-causing bacteria in prosthetic joints that require surgical revision has been developed by researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH). view more (2008-03-04)
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