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Arthritis Current Events | Arthritis News | 12

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Exercise improves functional and psycological ability and reduces steroid need in rheumatoid arthritis
Undertaking a supervised exercise programme can have beneficial effects on functional status and physical function, reduce the need for daily corticosteroid and anti-inflammatory intake and improve levels of depression and anxiety in people with rheumatoid arthritis (RA).   view more (2009-06-11)

Scientists solve mystery of polyketide drug formation
Many top-selling drugs used to treat cancer and lower cholesterol are made from organic compounds called polyketides, which are found in nature but historically difficult for chemists to alter and reproduce in large quantities.   view more (2008-04-02)

UCSD study of nuclear receptors could change anti-inflammatory treatments
Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).   view more (2005-09-09)

High-Trauma Fractures in Older Men and Women Linked to Osteoporosis
Researchers at the California Pacific Medical Center (CPMC) Research Institute are challenging a widely held belief that fractures resulting from major trauma, such as automobile accidents, are not related to osteoporosis, the common disease that makes bones weak and prone to fracture.   view more (2007-11-29)

SLU researchers show how to stop muscle weakness caused by myasthenia gravis
Severe muscle weakness caused by myasthenia gravis - a highly debilitating autoimmune disorder - can be prevented or reversed by blocking a key step in the immune response that brings on the disease, researchers at the Saint Louis University School of Medicine have found.   view more (2007-12-21)

Popular Arthritis Drug May Disrupt Heart Rhythm, UB Research Finds
Celebrex, a popular arthritis drug that blocks pain by inhibiting an enzyme known as COX-2, has been shown in laboratory studies to induce arrhythmia, or irregular beating of the heart, via a novel pathway unrelated to its COX-2 inhibition.   view more (2008-01-25)

Study helps explain how allergic reactions are triggered
In demonstrating that a group of calcium ion channels play a crucial role in triggering inflammatory responses, researchers at Beth Israel Deaconess Medical Center (BIDMC) have not only solved a longstanding molecular mystery regarding the onset of asthma and allergy symptoms, but have also provided a fundamental discovery regarding the... view more... (2008-01-15)

Research Shows Cherry Juice May Prevent Muscle Damage Pain
The familiar "no pain, no gain" phrase usually associated with exercise may be a thing of the past if results from a study on cherry juice published today in the online version of the British Journal of Sports Medicine prove true in future research.   view more (2006-06-23)

Psoriasis associated with cardiovascular disease and increased mortality
The skin disease psoriasis is associated with atherosclerosis (a buildup of plaque in the arteries) characterized by an increased prevalence of ischemic heart disease, cerebrovascular disease, peripheral artery disease and an increased risk of death.   view more (2009-06-16)

A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases
The same signal responsible for promoting the type of immune responses that cause asthma and allergy can also limit the type of inflammation associated with debilitating diseases like inflammatory bowel disease, arthritis and multiple sclerosis.   view more (2006-04-10)

New 'biofactories' produce rare healing substances in the endangered Devil's claw plant
Deep in Africa's Kalahari Desert lies the "Devil's claw," a plant that may hold the key to effective treatments for arthritis, tendonitis and other illnesses that affect millions each year.   view more (2009-08-17)

Monoclonal antibody reduces exacerbations in asthmatics
Patients with symptomatic moderate asthma who were treated with anti-tumor necrosis factor alpha, an anti-inflammatory monoclonal antibody, experienced significantly fewer disease exacerbations than individuals taking a placebo.   view more (2006-10-02)

Drug banned by sports may be good for oldies
A world-first pilot study suggests that anabolic steroids, best known for doping in sports, may in fact help older people recover better after joint replacement surgery.   view more (2006-06-15)

Specific antagonism lowers blood pressure
High blood pressure (hypertension) is associated with an increased risk of heart attack and stroke, and the frequent use of drugs known as NSAIDs, for example to treat individuals with rheumatoid arthritis, can cause hypertension.   view more (2007-08-17)

“Shooting the messenger” to tackle autoimmune diseases
AIDS and other autoimmune diseases could be tackled with a range of new drugs that stop cells recognising certain chemical messages in blood, says Dr Gerry Graham from the Glasgow-based Institute for Cancer Research speaking at the BA Festival of Science today [3 September 2001]. Autoimmune diseases, including rheumatoid arthritis, multiple... view more... (2001-08-30)

Molecular switch the key to disease breakthroughs on many fronts
A single molecular switch may be the key to fighting disease on several fronts. Research published in SCIENCE this week, suggests that the blocking of one signalling pathway may be crucial in tackling auto-immune disease, transplant rejection and leukaemia. Having identified a small family of signalling molecules that play an important role in... view more... (2002-07-16)

Extra care for outwardly healthy workers costs companies millions annually
Someone healthy enough to work could still cost an employer more than $4,000 annually in unnecessary health care costs.   view more (2009-10-23)

Scientists Discover Role of Enzyme in DNA Repair
Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), and Integrative Bioinformatics Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the body's ability to repair damaged DNA. NIAMS and NCI are part... view more... (2007-06-28)

Better access to info and dialogue with HCPs on sexual issues for rheumatology patients
Patients with rheumatic diseases want more information and better communication with healthcare professionals on the sexual issues related to their conditions.   view more (2009-06-12)

Experimental approach may reverse rheumatoid arthritis and osteoporosis
Researchers have identified a mechanism that may keep a well known signaling molecule from eroding bone and inflaming joints, according to an early study published online today in the Journal of Clinical Investigation.    view more (2009-09-22)
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