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New anti-thrombotic therapy effective, safer for patients
A Canadian-led study involving researchers from 41 countries has demonstrated in the world's largest study of acute coronary syndromes (ACS) that a new anti-thrombotic therapy is safer and as effective as the traditional therapy used in preventing heart attacks, death and ischemia in people with serious heart conditions.   view more (2005-09-06)

Nicorandil Could Improve Outcome For Angina Patients
Results of a UK study in this week's issue of THE LANCET suggest that the antianginal drug nicorandil could reduce the risk of cardiovascular disease associated with angina. Angina occurs in 10% of men aged older than 60 years in the UK (10-15 years later in women), and is a common underlying cause of coronary heart disease (CHD). Aspirin,... view more... (2002-04-10)

UCSD researchers create roadmap to integrin activation
Calling it an important technical advance in the study of the complex receptors and pathways of the body's cellular system, researchers at the University of California, San Diego (UCSD) School of Medicine have reconstructed the signaling pathways that impact activation of a receptor that is critical to the control of bleeding and to the thrombosis... view more... (2006-09-18)

Anti-inflammatory drugs may mask prostate cancer marker
Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, may reduce serum levels of the prostate biomarker, PSA (prostate specific antigen), and hence may alter the detection of prostate cancer in individuals who take these medications.   view more (2008-09-08)

Combining NSAIDs with chemotherapy, radiation may improve cancer treatment
Until recently, nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and celecoxib (sold as Celebrex), were being hailed as promising cancer prevention drugs.   view more (2007-05-18)

Smoking and caffeine inversely associated with Parkinson's disease
Individuals with Parkinson's disease are less likely to smoke or consume high doses of caffeine than their family members who do not have the disease, according to a report in the April issue of Archives of Neurology, one of the JAMA/Archives journals.   view more (2007-04-10)

Professor Tom Meade Wins The Second MRC Millennium Medal For Outstanding Contribution To Uk Health
Professor Tom Meade, epidemiologist, visionary researcher and clinician, will be awarded the Medical Research Council's second Millennium Medal for outstanding contribution to UK health this evening (Tuesday 23 July 2002). Professor Meade's work on coagulation overturned conventional wisdom about the systems in the body which contribute to... view more... (2002-07-23)

The mechanism of the life-threatening drug-interaction of Bayer's cholesterol-lowering agent Lipobay/Baycol clarified
Researchers from Finland have found that the cholesterol-lowering agent gemfibrozil (marketed as Lopid and generics) greatly increases the concentrations of cerivastatin (Lipobay or Baycol) in blood. This finding explains the observed muscle toxicity of the gemfibrozil-cerivastatin combination. This potentially fatal adverse effect of cerivastatin... view more... (2002-12-16)

Could Healthy Eating Cause Stress?
The health benefits of antioxidants in foods including red wine, vitamin E and even tea have been widely researched over the last twenty years, fuelled by evidence that oxidative damage may be implicated in many diseases.   On Monday 12 April, 17.30, Dr Edwin N. Frankel, University of California, will explore 'Antioxidants: past,... view more... (2002-04-12)

Best use of drug-eluting stents
Compared with bare metal stents, drug-eluting stents substantially reduce the risk of angiographic and clinical recurrence but do not affect mortality or the short term or long term risk of myocardial infarction.   view more (2008-09-02)

One in five older British women has heart disease
One in five older British women has cardiovascular disease, including stroke or blocked arteries, which is higher than previously thought, finds research in the Journal of Epidemiology and Community Health. And the high prevalence of risk factors among them is not matched by levels of preventive treatment, shows the research. The findings are... view more... (2003-01-21)

Quality improvement effort pays off in diabetes care
Spending money to improve diabetes care at federally qualified community health centers is a sound investment, according to one of the first studies to examine the clinical and economic impact of quality improvement on diabetes care.   view more (2007-05-18)

When does context matter in product evaluations?
In most real world settings, consumers encounter and evaluate products in mixed environments - aspirin and deodorant shelved side-by-side at a pharmacy, or an ad for a tropical vacation next to fashion spread in a magazine.   view more (2008-03-18)

Updated guideline: Carotid endarterectomy beneficial for stroke prevention in some patients
Carotid endarterectomy is the most frequently performed operation to prevent stroke. There is scientific evidence to support its use to prevent future stroke.   view more (2005-09-27)

Painkillers may threaten power of vaccines
With flu-shot season in full swing and widespread anticipation of the HPV vaccine to prevent cervical cancer, a new University of Rochester study suggests that using common painkillers around the time of vaccination might not be a good idea.   view more (2006-11-29)

Chest Pain Center Accreditation Linked with Better Outcomes in Heart Attack Patients
Hospitals accredited by the Society of Chest Pain Centers (SCPC) have been shown to perform better in the heart attack core measures established by Centers for Medicare and Medicaid Services (CMS) as compared to non-accredited hospitals, according to a national study led by an Emory University researcher.   view more (2008-07-10)

Applying mathematics to industry
A recently established centre at the University of Leicester is gearing up to meet the needs of business and industry through a new outreach programme.   view more (2002-10-29)

New blood clot guidelines for pregnant women
New evidence-based guidelines address the prevention and management of thrombosis in key patient populations and reinforce recommendations related to the routine use of preventive therapies.   view more (2008-06-25)

Safety of antithrombotic treatment in acute coronary syndromes
The management of acute coronary syndromes (with or without ST segment elevation) requires the use of anticoagulants, antiplatelet agents (aspirin, clopidogrel and/or glycoprotein (GP) IIb/IIIa inhibitors), beta-blockers, thrombolytics in some cases, and revascularization / reperfusion.   view more (2008-09-03)

Chemical in red wine, fruits and vegetables stops cancer, heart disease, depending on the dose
The next cancer drug might come straight from the grocery store, according to new research published in the November 2007 issue of The FASEB Journal. In the study, French scientists describe how high and low doses of polyphenols have different effects. Most notably, they found that very high doses of antioxidant polyphenols shut down and prevent... view more... (2007-10-30)
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