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Adding ezetimibe to atorvastatin improves lipid control
Adding ezetimibe to atorvastatin significantly boosted the attainment of lipid targets as specified by both Canadian and European guidelines in elderly patients aged 65 and older and the combination produced superior results than simply increasing the dose of atorvastatin alone. view more (2009-10-27)
INEGY™ (Ezetimibe/Simvastatin) Receives First Approval in Europe
Merck & Co., Inc. and Schering-Plough Corporation today announced the regulatory approval of INEGY™ in Germany. INEGY is the first product to reduce low-density lipoprotein cholesterol (LDL-C or 'bad' cholesterol) through Dual Inhibition of both cholesterol production in the liver and absorption in the intestine. Germany is the first... view more... (2004-04-02)
Early signs that statins could help in treatment of rheumatoid arthritis (pp 2011, 2015)
Results of a UK study in this week's issue of THE LANCET suggest that the anti-inflammatory effect of statins (a class of cholesterol-lowering drugs) could be effective in relieving symptoms of rheumatoid arthritis. The inflammatory nature of rheumatoid arthritis puts sufferers at an increased risk of cardiovascular disease.... view more... (2004-06-16)
Statin therapy ineffective in breast cancer prevention
Laboratory work in animals showed limited activity when statins were given to prevent breast cancer, according to a report in the February issue of Cancer Prevention Research, a journal of the American Association for Cancer Research. view more (2009-02-05)
Statins Could Reduce Risk Of Cardiovascular Disease
The benefit of statins to prevent cardiovascular disease could extend to people receiving therapy for high blood pressure, conclude authors of an international study published in THE LANCET this week.1 Statins (a class of cholesterol-lowering drugs) are well known for their effectiveness in reducing cardiovascular risk. No study, however, has... view more... (2003-03-31)
Combination HDL/LDL therapy has no effect on plaque build-up
For some patients with high cholesterol, even the most aggressive treatment with statin drugs fails to prevent coronary artery disease. Patients with hyperlipidemia - high LDL or "bad" cholesterol and trigylcerides, and low HDL or "good" cholesterol - and those with a family history of high cholesterol are at a high risk for... view more... (2007-03-27)
AGGRESSIVE LIPID-LOWERING THERAPY IS MORE EFFECTIVE IN REDUCING ATHEROSCLEROSIS (pp 574, 577)
The risk of atherosclerosis in people with high blood cholesterol could be reduced by aggressive lipid-lowering therapy, conclude authors of a study in this week's issue of THE LANCET. High LDL-cholesterol (the "bad" cholesterol) is a risk factor for atherosclerosis, which in turn is a risk factor for coronary artery disease (CAD). Tineke Smilde... view more... (2001-02-21)
Simvastatin -- For hearts and minds?
Statins are not all equal when it comes to their potential to guard against dementia, according to a study published in the online open access journal BMC Medicine. view more (2007-07-19)
Study suggests statins reduce cardiovascular risk for people with type 2 diabetes (p 641, 685)
Results of a randomised trial in this week's issue of THE LANCET suggest that people with type 2 diabetes could benefit from cholesterol-lowering therapy with statins to reduce the risk of cardiovascular disease-even when they do not have high cholesterol concentrations. Many recent studies have shown the benefits of statin therapy to reduce the... view more... (2004-08-18)
Popular statin reduces recurrent stroke risk
In people who have experienced a stroke, but who have no known history of coronary heart disease, beginning regular treatment with the cholesterol-lowering drug atorvastatin soon after the stroke can reduce the risk of recurrent stroke by 16 percent. view more (2006-08-10)
Despite significantly raising HDL, torcetrapib failed to slow the progression of coronary plaques
Investigators reported today that torcetrapib, a drug that substantially raises high-density lipoprotein cholesterol or HDL (the "good" cholesterol), did not slow the progression of plaque buildup in the coronary arteries as measured using an ultrasound probe (IVUS). view more (2007-03-27)
One pill may be better than two for treating patients with high blood pressure
Adults with high blood pressure and additional risk factors for heart disease may benefit more from taking one tablet rather than two, if their current treatment combines the lipid-lowering medication atorvastatin with the blood pressure-lowering medication amlodipine. view more (2007-05-14)
Study finds drug can cut chance of a heart attack by more than a third
Results from the ASCOT (Anglo Scandinavian Cardiac Outcome Trial) study have shown that patients receiving the cholesterol controlling drug, atorvastatin, are more than a third less likely to have heart attacks, and more than a quarter less likely to suffer from strokes. The results of the study, announced today at the American College of... view more... (2003-03-31)
No reason to fear very low LDL
Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies, according to a new study in the Oct. 18, 2005, issue of the Journal of the American College of Cardiology. view more (2005-10-12)
Atorvastatin shown to decrease heart disease and stroke in patients with hypertension and low cholesterol
Issued on behalf of the International Steering Committee of the Anglo-Scandinavian Cardiac Outcomes Trial A major European trial studying different blood pressure treatments and the effects of additional cholesterol lowering, announces today that it has stopped part of its trial earlier than expected because results collected already show a... view more... (2002-10-10)
Cholesterol-lowering drugs not associated with increased breast cancer risk
A report being published in the Journal of the National Cancer Institute found that women who took statins-the widely used cholesterol lowering drugs-do not face an increased breast cancer risk as had been suggested by some previous studies. view more (2006-05-17)
DNA vaccine against multiple sclerosis appears safe, potentially beneficial
A newly developed DNA vaccine appears safe and may produce beneficial changes in the brains and immune systems of individuals with multiple sclerosis. view more (2007-08-14)
The Lancet Neurology - January 2003
STROKE IN THE 21st CENTURY In the first issue of 2003, TLN examines stroke epidemiology and stroke trials. In their review, Valery Feigin and co-authors provide an overview of population-based studies of incidence, prevalence, mortality, and case-fatality of stroke based on studies reported between 1996 and 2002. From their analysis the authors... view more... (2002-12-18)
Researchers find specific statin significantly reduces Alzheimer's and Parkinson's disease risk
Researchers from Boston University School of Medicine (BUSM) have found that the statin, simvastatin, reduces the incidence of Alzheimer's disease and Parkinson's disease by almost 50 percent. view more (2007-07-19)
Combining multiple treatments improves multiple sclerosis therapy
Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system (CNS) in which white blood cells known as lymphocytes attack the myelin insulation on nerves in the spinal cord and brain. view more (2006-03-17)
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