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Chopped up proteins trigger autoimmunity
Dutch biochemist Geurt Schilders has mapped several proteins that can regulate the activity of the human exosome and which play a role in the degradation of RNA molecules.   view more (2008-01-25)

Lung airway cells activate vitamin D and increase immune response
Vitamin D is essential to good health but needs to be activated to function properly in the human body. Until recently, this activation was thought to happen primarily in the kidneys, but a new University of Iowa study finds that the activation step can also occur in lung airway cells.   view more (2008-11-04)

UT researcher: Interferon alpha can delay full onset of type I diabetes
A low dose of oral interferon alpha shows promise in preserving beta cell function for patients with newly diagnosed type 1 diabetes, or juvenile diabetes.   view more (2009-07-01)

Master gene that switches on disease-fighting cells identified by scientists
The master gene that causes blood stem cells to turn into disease-fighting 'Natural Killer' (NK) immune cells has been identified by scientists, in a study published in Nature Immunology today.   view more (2009-09-14)

Study Identifies Genetic Risk Factor for Rheumatoid Arthritis, Lupus
A genetic variation has been identified that increases the risk of two chronic, autoimmune inflammatory diseases: rheumatoid arthritis (RA) and systemic lupus erythematosus (lupus).   view more (2007-09-07)

Lancet Study Supports New, Highly Effective Treatment for Blood Disorder
Patients suffering from a blood disorder that prevents proper clotting have the option of a new medication that may dramatically improve their health.   view more (2009-03-23)

Eight new genes linked to diabetes; the understanding of a financial and health monster
Eight genes, normally associated with normal pancreatic functions, are linked with susceptibility to diabetes Type 2 reports a team of investigators in the last issue of the PLoS Biology Journal. In'™s Barroso and colleagues at the University of Cambridge, United Kingdom studied 71 genes on more than 2000 individuals, trying to correlate... view more... (2003-11-28)

Modified bone marrow cells can help recovery in an animal model of multiple sclerosis
A new study published in PLoS Medicine has shown that modified bone marrow cells can help recovery in an animal model of multiple sclerosis (MS).   view more (2007-04-10)

Largest gene study of childhood IBD identifies 5 new genes
In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in a biological pathway that helps drive the painful inflammation of the digestive tract that characterizes the disease.   view more (2009-11-16)

Minuscule molecules pack a powerful punch
A role for a microRNA in the immune system has been shown by study of one of the world's first microRNA knockout mouse, reported Friday 27 April in Science.   view more (2007-04-27)

St. Jude finds molecule that could improve cancer vaccines and therapy for other diseases
Investigators at St. Jude Children's Research Hospital have discovered a new signaling molecule that prevents immune responses from running amok and damaging the body.   view more (2007-11-26)

Carnegie Mellon MRI technology that non-invasively locates, quantifies specific cells in the body
Magnetic resonance imaging (MRI) isn't just for capturing detailed images of the body's anatomy. Thanks to novel imaging reagents and technology developed by Carnegie Mellon University scientist Eric Ahrens, MRI can be used to visualize - with "exquisite" specificity - cell populations of interest in the living body.   view more (2008-08-22)

Small molecules may explain psoriasis
A research team at the Swedish medical university Karolinska Institutet has shown for the time that microRNA, small RNA molecules, may play an important role in the development of inflammatory skin diseases such as psoriasis and atopic eczema.   view more (2007-07-12)

Hopes raised for effectiveness of multiple sclerosis drug
Discovery of the mechanism of a drug being tested for the treatment of multiple sclerosis (MS) has revealed that it's not only more effective than first thought, but might also help in the management of other autoimmune diseases, organ transplant rejection and even cancer.   view more (2006-03-29)

Geisinger research: Antimalarial drug prevents diabetes in arthritis patients
The use of an antimalarial medication may prevent the onset of diabetes in patients with rheumatoid arthritis, new Geisinger research shows.   view more (2008-10-29)

Firefly protein lets researchers monitor molecule linked to cancer
Scientists have used a glowing protein from fireflies to observe the activity of a molecule that is an important target for new drugs to treat cancer, autoimmune diseases and several other disorders.   view more (2005-08-10)

Over-the-Counter Arthritis Drug Glucosamine Might Also Help Against MS
Glucosamine, the over-the counter natural product that has been touted to help with joint and cartilage problems associated with arthritis, may also provide some relief to individuals with multiple sclerosis (MS), a degenerative, nervous system disease with no known cure.   view more (2005-11-29)

New insight into machinery of immune cells' 'tentacles'
Researchers have identified new molecular components of the machinery that regulates formation of the tentacle-like filaments by which immune system T cells grasp other cells.   view more (2006-01-10)

Immune responses spread from one protein to another in type 1 diabetes
Type 1 diabetes (T1D) is caused by the immune system inappropriately attacking the cells in the pancreas that produce insulin, the hormone that controls blood sugar levels.   view more (2006-12-04)

The risk factors of idiopathic pulmonary fibrosis in HCV patients
Hepatitis C virus (HCV) is one of the more common causes of chronic liver disease in world with a variety of extrahepatic complications such as essential mixed cryoglobulinemia, membranoproliferative glomerulonep hritis, autoimmune thyroiditis, sialadenitis, and cardiomyopathy.   view more (2008-10-23)
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