Autoimmune Current Events | Autoimmune News | 8
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Jefferson neuroscientists show anti-inflammation molecule helps fight MS-like disease
An immune system messenger molecule that normally helps quiet inflammation could be an effective tool against multiple sclerosis (MS). Neurology researchers led by Abdolmohamad Rostami, M.D., Ph.D., professor and chair of the Department of Neurology at Jefferson Medical College of Thomas Jefferson University and the Jefferson Hospital for... view more... (2007-11-12)
Scientists stop autoimmune disease without shutting off immune system
Skin is our first line of defense against infection. But people with a rare, life-threatening autoimmune disease called pemphigus vulgaris lack that protection because their immune system attacks the proteins that hold skin cells together. view more (2006-08-23)
Cause of nerve fiber damage in multiple sclerosis identified
Researchers have identified how the body's own immune system contributes to the nerve fiber damage caused by multiple sclerosis, a finding that can potentially aid earlier diagnosis and improved treatment for this chronic disease. view more (2006-10-17)
Researchers identify new risk factor gene for rheumatoid arthritis
Scientists at The Feinstein Institute for Medical Research and a team of collaborators from across the country have identified a new risk factor gene for rheumatoid arthritis. view more (2009-06-10)
Regulatory B cells exist -- and pack a punch
Researchers at Duke University Medical Center have uncovered definitive evidence that a small but potent subset of immune system B cells is able to regulate inflammation. view more (2008-05-28)
Protein helps immune cells to divide and conquer
Researchers at the University of California, San Diego School of Medicine have identified a key protein that is required for immune cells called B lymphocytes to divide and replicate themselves. The rapid generation of large numbers of these immune cells is critical to the body's antibody defense mechanism. view more (2009-03-09)
Why doesn't the immune system attack the small intestine?
Answering one of the oldest questions in human physiology, researchers at Dana-Farber Cancer Institute have discovered why the body's immune system-perpetually on guard against foreign microbes like bacteria - doesn't attack tissues in the small intestine that harbor millions of bacteria cells. view more (2007-01-10)
Strengthening the tumor-fighting ability of T cells
When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor. But these killer cells often fail to completely eliminate the tumor because they're deactivated by a distinct population of T cells known as regulatory T cells. view more (2008-03-25)
Suspected cause of type 1 diabetes caught
Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes. view more (2008-05-12)
Scientists discover a direct route from the brain to the immune system
It used to be dogma that the brain was shut away from the actions of the immune system, shielded from the outside forces of nature. But that's not how it is at all. In fact, thanks to the scientific detective work of Kevin Tracey, MD, it turns out that the brain talks directly to the immune system, sending commands that control the body's... view more... (2007-10-24)
Implants mimic infection to rally immune system against tumors
Bioengineers at Harvard University have shown that small plastic disks impregnated with tumor-specific antigens and implanted under the skin can reprogram the mammalian immune system to attack tumors. view more (2009-01-23)
Old mystery solved, revealing origin of regulatory T cells that 'police' and protect the body
More than 150 years after the discovery of Hassall's corpuscles in 1849, the function of these round blobs of cells in the human thymus gland has now been explained. The answer, in turn, ends an intense hunt for the origin of regulatory T cells that has been under way for years. view more (2005-10-13)
Autoimmune response can induce pancreatic tumor rejection
Immune responses are capable of killing tumors before they can be directed toward normal body tissue, according to new scientific findings published in Cancer Research, a journal of the American Association for Cancer Research. view more (2009-09-09)
Natural, soy-based substance might help fight MS, Jefferson neuroscientists find
A natural substance made from soy appears to have amazing restorative powers when given to animals with a multiple sclerosis (MS)-like disease. view more (2006-12-13)
Rheumatic disease increases risks in pregnancy, Stanford study finds
The first nationwide study of pregnancy outcomes in women with rheumatic disease confirms that they experience greater pregnancy risks and longer hospital stays than the average pregnant woman. view more (2005-11-15)
Ovarian function and fertility preserved in women with severe systemic lupus erythematosus
Ovarian function can be preserved and disease activity controlled in women with severe systemic lupus erythematosus (SLE) when treated with a 6-month course of cyclophosphamide (CYC), a chemotherapy drug, followed by the immunosuppressant mycophenolate mofetil (MMF). view more (2008-06-13)
University of Pennsylvania Researchers Identify Gatekeeper Involved in Chronic Inflammatory Diseases
he road to many an inflammatory disease is guarded by a cytokine messenger protein called interleukin-27, according to researchers from the University of Pennsylvania School of Veterinary Medicine. Chronic inflammation results when the immune system becomes over stimulated and begins attacking healthy tissue in excess. view more (2006-08-22)
Downstate researchers target multiple sclerosis
Researchers at SUNY Downstate Medical Center have developed a substance that inhibits the progress of multiple sclerosis (MS) in an animal model. The agent, a novel calpain inhibitor, can be administered orally. view more (2006-11-22)
New discovery may improve treatment of one of the world's leading causes of blindness
An inflammatory eye condition that is one of the world's leading causes of blindness could be treated much more effectively and easily thanks to a new discovery here. view more (2007-10-01)
Subclinical markers predict relapse in juvenile idiopathic arthritis post methotrexate withdrawal
Elevated levels of the inflammatory biomarkers Myeloid Related Protein (MRP) 8/14 predict an increased risk of relapse following withdrawal of methotrexate (MTX) therapy in children with juvenile idiopathic arthritis (JIA) who have achieved inactive disease status. view more (2009-06-11)
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