Autoimmune Disease Current Events | Autoimmune Disease News | 4
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St. Jude study shows how T cell's machinery dials down autoimmunity
A St. Jude Children's Research Hospital study shows that T cells, the body's master immune regulators, do not use simple on/off switches to govern the cellular machinery that regulates their development and function. Rather, they possess sophisticated molecular controls that enable them to adjust their function with exquisite precision. view more (2008-05-13)
Mayo researchers lead team that discovers role of dendritic cells in childhood autoimmune disease
Mayo Clinic researchers, working with colleagues at the University of Minnesota and University of Pittsburgh, are the first to describe a new role for a specialized cell of the immune system in children suffering from a rare muscle-damaging disease known as juvenile dermatomyositis (JDM). view more (2005-11-14)
Stanford study identifies cellular mechanism that causes lupuslike symptoms in mice
Macrophages, the scavenger cells of the body's immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease. view more (2009-10-19)
Preventing toxic side effects of inflammatory disease therapy
Researchers at the University of California, San Diego (UCSD) School of Medicine have developed a mouse model that could help scientists develop better drugs to fight autoimmune and inflammatory disorders such as multiple sclerosis and rheumatoid arthritis. view more (2006-02-09)
Identification of chemokines and cytokines offers new hope for inflammatory myopathy patients
The inflammatory myopathies comprise three different entities: polymyositis, inclusion body myositis and dermatomyositis. People in all age groups can be affected by major muscle weakness and pain, and show evidence of muscle fiber breakdown in the serum. Autoimmune pathogenetic mechanisms have been identified in each inflammatory myopathy, but... view more... (2002-09-10)
Don't be a stranger to yourself
One of the most important tasks of the immune system is to identify what is foreign and what is self. If this distinction fails, then the body's own structures will be attacked, the result of which could be an autoimmune disease such as diabetes mellitus type 1 or multiple sclerosis. view more (2009-03-16)
Researchers investigate ways to detect lupus-associated kidney disease
High urinary levels of certain molecules might have the potential to serve as biomarkers for a potentially life-shortening kidney ailment caused by the autoimmune disease lupus, UT Southwestern Medical Center researchers have found. view more (2007-11-14)
Stem cell transplant can grow new immune system in certain mice, Stanford researchers find
Researchers at the Stanford University School of Medicine have taken a small but significant step, in mouse studies, toward the goal of transplanting adult stem cells to create a new immune system for people with autoimmune or genetic blood diseases. view more (2007-11-26)
New study shows antibody-interleukin complexes stimulate immune responses
The findings could also be significant for developing new ways to help patients with autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, or juvenile diabetes. view more (2006-02-23)
Type 1 diabetes triggered by 'lazy' regulatory T-cells: McGill researchers
A research team led by Dr. Ciriaco A. Piccirillo of McGill University's Department of Microbiology and Immunology has discovered that in some individuals, the specialized immunoregulatory T-cells that regulate the body's autoimmune reactions may lose their effectiveness and become "lazy" over time, leading to the onset of type 1 diabetes. view more (2008-01-16)
Promising new target emerges for autoimmune diseases
University of Michigan scientists say they have uncovered a fundamentally new mechanism that holds in check aggressive immune cells that can attack the body's own cells. view more (2009-09-02)
Deficient regulators in the immune system responsible for type 1 diabetes
The main regulators of the immune system, called CD4+Treg cells, are thought to be highly involved in a large range of immune diseases. view more (2008-01-25)
Penn researchers provide insights into how the immune system avoids attacking itself
A finding by University of Pennsylvania School of Medicine researchers about how immune cells "decide" to become active or inactive may have applications in fighting cancerous tumors, autoimmune diseases, and organ transplant rejection. view more (2006-10-13)
Natural immune-control system may aid treatment of autoimmune disease and tissue rejection
The immune system's ability to police itself may offer a new method of arresting the cells responsible for autoimmune diseases such as multiple sclerosis and for the rejection of transplanted organs and tissues. view more (2007-05-18)
“Shooting the messenger” to tackle autoimmune diseases
AIDS and other autoimmune diseases could be tackled with a range of new drugs that stop cells recognising certain chemical messages in blood, says Dr Gerry Graham from the Glasgow-based Institute for Cancer Research speaking at the BA Festival of Science today [3 September 2001]. Autoimmune diseases, including rheumatoid arthritis, multiple... view more... (2001-08-30)
DASNR researchers make breakthrough against poxviruses
Smallpox has a nasty history throughout the world. Caused by poxviruses, smallpox is one of the few disease-causing agents against which the human body's immune system is ineffective in its defense. view more (2009-01-26)
Finding paves way for better treatment of autoimmune disease
A signaling molecule with an affinity for alcohol has yielded a rapid, inexpensive way to make large numbers of immune cells that work like beat cops to keep misguided cells from attacking the body. view more (2006-08-10)
Blood pressure medication to treat multiple sclerosis?
Conventional blood pressure medication can treat inflammation in an animal model mimicking multiple sclerosis (MS). This discovery was made by Dr. Michael Platten, head consultant at the department of Neurooncology at Heidelberg University Hospital and head of the Helmholtz Experimental Neuroimmunology Junior Research Group on at the German Cancer... view more... (2009-08-19)
MGH initiates phase I diabetes trial
Scientists at the Massachusetts General Hospital (MGH) have initiated a phase 1 clinical trial to reverse type 1 diabetes. view more (2008-03-14)
Scientists Learn the Origin of Rogue B Cells
Doctors have long wondered why, in some people, the immune system turns against parts of the body it is designed to protect, leading to autoimmune disease. view more (2007-02-08)
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