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Regulatory T cells require WASp if they are to prevent self-destruction
In humans, mutation of the gene encoding a protein known as WASp leads to susceptibility to infections and systemic autoimmunity. view more (2007-01-12)
The genetic basis for autoimmunity discovered
Researchers from the Basque University have discovered the relationship between E2F2 gene and autoimmunity. The Science Faculty team, leaded by Ana Zubiaga has published the results of its researches in the fifteenth issue of the Immunity magazine. The team began analysing E2F2 gene and its family. This gene family is responsible for the cell... view more... (2002-03-01)
Autoimmune response can induce pancreatic tumor rejection
Immune responses are capable of killing tumors before they can be directed toward normal body tissue, according to new scientific findings published in Cancer Research, a journal of the American Association for Cancer Research. view more (2009-09-09)
Scientists Develop Method to Track Immune System Enzyme in Live Animals
Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity... view more... (2007-05-18)
Omega fatty acid balance can alter immunity and gene expression
For the past century, changes in the Western diet have altered the consumption of omega-6 fatty acids (w6, found in meat and vegetable oils) compared with omega-3 fatty acids (w3, found in flax and fish oil). view more (2009-06-01)
Study aims to induce recovery from ankylosing spondylitis
Chinese patients will soon have the opportunity to take part in a study of a novel therapy aimed at reversing the autoimmune disease, ankylosing spondylitis. view more (2009-07-22)
Visionary concept earns La Jolla Institute scientist prestigious NIH Pioneer Award
A scientist at the La Jolla Institute for Allergy & Immunology has received one of the National Institutes of Health (NIH)'s top awards -- the 2009 NIH Director's Pioneer Award. view more (2009-09-24)
Protein may be linked to melanoma recurrence
Higher levels of a protein called S-100 in patients with melanoma may correlate with a higher risk of having the disease return. view more (2007-06-04)
'Autoantibodies' may be created in response to bacterial DNA
Autoimmune diseases have long been regarded as illnesses in which the immune system creates autoantibodies to attack the body itself. view more (2009-04-28)
Common bacteria activating natural killer T cells may cause autoimmune liver disease
A bacteria commonly found in soil and water triggered autoimmune symptoms in mice similar to those found in an incurable liver disease called Primary Biliary Cirrhosis (PBC). view more (2008-05-15)
Genetic study confirms the immune system's role in narcolepsy
Scientists funded by the National Institutes of Health have identified a gene associated with narcolepsy, a disorder that causes disabling daytime sleepiness, sleep attacks, irresistible bouts of sleep that can strike at any time, and disturbed sleep at night. view more (2009-05-04)
New scientific knowledge on juvenile diabetes
Finnish scientists have reported a breakthrough in the attempts to understand the development of type 1 diabetes. They discovered disturbances in lipid and amino acid metabolism in children who later progressed to type 1 diabetes, also known as juvenile diabetes. view more (2008-12-18)
Worm parasite may hold clues in bid for illness and allergy cures
Tiny worms that can trick the body's natural defences could hold the key to new treatments for a range of conditions, including diabetes, asthma and hay fever. view more (2005-11-08)
Vitamin D may exacerbate autoimmune disease
Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but a review appearing in Autoimmunity Reviews explains that low levels of vitamin D in patients with autoimmune disease may be a result rather than a cause of disease and that supplementing with vitamin D may actually exacerbate autoimmune disease. view more (2009-04-09)
Scripps research scientists find new genetic mutation that halts the development of lupus
The lupus-suppressing action is the result of what is known as a nonsense mutation of the Coronin-1A gene (Coro1a) required for the development of the disease. view more (2008-01-18)
Strengthening the tumor-fighting ability of T cells
When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor. But these killer cells often fail to completely eliminate the tumor because they're deactivated by a distinct population of T cells known as regulatory T cells. view more (2008-03-25)
Don't be a stranger to yourself
One of the most important tasks of the immune system is to identify what is foreign and what is self. If this distinction fails, then the body's own structures will be attacked, the result of which could be an autoimmune disease such as diabetes mellitus type 1 or multiple sclerosis. view more (2009-03-16)
Study Tests Oral Insulin to Prevent Type 1 Diabetes
Researchers have begun a clinical study of oral insulin to prevent or delay type 1 diabetes in at-risk people, the National Institutes of Health (NIH) announced today. view more (2007-02-01)
Antibody-altering protein found in developing B cells
In order for the B cells of the immune system to identify and fight disease pathogens, they produce a protein called activation-induced cytidine deaminase (AID). view more (2007-07-20)
Automimmune response more common in people with severe coronary heart disease
The development of severe coronary artery disease may be part of a systemic autoimmune response, suggests research in the Annals of the Rheumatic Diseases. view more (2002-01-15)
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