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Regulatory T cells require WASp if they are to prevent self-destruction
In humans, mutation of the gene encoding a protein known as WASp leads to susceptibility to infections and systemic autoimmunity.   view more (2007-01-12)

The genetic basis for autoimmunity discovered
Researchers from the Basque University have discovered the relationship between E2F2 gene and autoimmunity. The Science Faculty team, leaded by Ana Zubiaga has published the results of its researches in the fifteenth issue of the Immunity magazine. The team began analysing E2F2 gene and its... view more (2002-03-01)

Scientists Develop Method to Track Immune System Enzyme in Live Animals
Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in... view more (2007-05-18)

Protein may be linked to melanoma recurrence
Higher levels of a protein called S-100 in patients with melanoma may correlate with a higher risk of having the disease return.   view more (2007-06-04)

Common bacteria activating natural killer T cells may cause autoimmune liver disease
A bacteria commonly found in soil and water triggered autoimmune symptoms in mice similar to those found in an incurable liver disease called Primary Biliary Cirrhosis (PBC).   view more (2008-05-15)

Worm parasite may hold clues in bid for illness and allergy cures
Tiny worms that can trick the body's natural defences could hold the key to new treatments for a range of conditions, including diabetes, asthma and hay fever.   view more (2005-11-08)

Scripps research scientists find new genetic mutation that halts the development of lupus
The lupus-suppressing action is the result of what is known as a nonsense mutation of the Coronin-1A gene (Coro1a) required for the development of the disease.   view more (2008-01-18)

Strengthening the tumor-fighting ability of T cells
When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor. But these killer cells often fail to completely eliminate the tumor because they're deactivated by a distinct population of T cells known as regulatory T cells.   view more (2008-03-25)

Study Tests Oral Insulin to Prevent Type 1 Diabetes
Researchers have begun a clinical study of oral insulin to prevent or delay type 1 diabetes in at-risk people, the National Institutes of Health (NIH) announced today.   view more (2007-02-01)

Antibody-altering protein found in developing B cells
In order for the B cells of the immune system to identify and fight disease pathogens, they produce a protein called activation-induced cytidine deaminase (AID).   view more (2007-07-20)

Automimmune response more common in people with severe coronary heart disease
The development of severe coronary artery disease may be part of a systemic autoimmune response, suggests research in the Annals of the Rheumatic Diseases.   view more (2002-01-15)

Specialized white blood cells coordinate first responders to viral infection
Just as fire engines arrive quickly at the scene to save people and property, the cells that fight viruses have to reach the site of an infection promptly to mount a protective response.   view more (2008-04-25)

Accumulated bits of a cell's own DNA can trigger autoimmune disease
A security system wired within every cell to detect the presence of rogue viral DNA can sometimes go awry, triggering an autoimmune response to single-stranded bits of the cell's own DNA, according to a report in the August 22nd issue of the journal Cell, a Cell Press publication.   view more (2008-08-22)

Sexual differences in immune response appear at puberty
The differences in the male and female immune responses, which make females more prone to autoimmune disease and males more subject to infections, are established during puberty.   view more (2006-02-22)

St. Jude study shows how T cell's machinery dials down autoimmunity
A St. Jude Children's Research Hospital study shows that T cells, the body's master immune regulators, do not use simple on/off switches to govern the cellular machinery that regulates their development and function. Rather, they possess sophisticated molecular controls that enable them to adjust... view more (2008-05-13)

Researchers at Children's Discover Connection between Allergic Diseases and Autoimmune Diseases
A new study by researchers at Children's and the University of Washington (UW) identifies a connection between allergic diseases such as atopic dermatitis, also known as eczema, and autoimmune diseases.   view more (2007-04-04)

Glue inside the cell: Ubiquitin builds up an immune response
Ubiquitin is a small protein, which can be attached to other cellular proteins, a process known as ubiquitination. Discoveries in the 1980 th on a key function of ubiquitination in the regulation of protein degradation where awarded with the Nobel Prize for chemistry in 2004.   view more (2007-10-22)

Stress can contribute to childhood diabetes
Stress and difficult life events in the family can contribute to the development of diabetes in children. A correlation between such mental duress and diabetes-related autoimmune activity has been established in studies at Linköping University. The studies involve 17,000 children born in... view more (2004-02-27)

Antibody therapy prevents type 1 diabetes in mice
University of Pittsburgh investigators have successfully prevented the onset of type 1 diabetes in mice prone to developing the disease using an antibody against a receptor on the surface of immune T-cells. According to the investigators.   view more (2007-01-09)

Finding suggests novel ways to boost vaccination or natural defenses
Our bodies rely on the production of potent, or 'high affinity', antibodies to fight infection. The process is very complex, yet Sydney scientists have discovered that it hinges on a single molecule, a growth factor, without which it cannot function.   view more (2008-07-08)

Epstein-Barr virus may be associated with multiple sclerosis
Young adults with high levels of antibodies against the Epstein-Barr virus, the virus that most often causes mononucleosis, may be more likely to develop multiple sclerosis 15 to 20 years later.   view more (2006-04-11)

Green tea may help prevent autoimmune diseases
Green tea may help protect against autoimmune disease, Medical College of Georgia researchers say.   view more (2007-04-20)

NIH scientists find a novel mechanism that controls the development of autoimmunity
Scientists at the National Institutes of Health (NIH) have found a mechanism in the immune systems of mice that can lead to the development of autoimmune disease when turned off.   view more (2008-08-14)

Gene for immune deficiency syndromes found
A newly discovered gene mutation may account for many cases of immune deficiency, in particular two syndromes known as immunoglobulin A (IgA) deficiency and Common Variable Immunodeficiency (CVID), report researchers in the July issue of Nature Genetics. The discovery may lead to a new diagnostic... view more (2005-07-11)

Link found between immune system and high plasma lipid levels
Researchers at the University of Chicago have found an unsuspected link between the immune system and high plasma lipid levels (cholesterol and triglycerides in the blood) in mice. The finding could lead to new ways to reduce the risk of heart disease by lowering elevated lipid levels.   view more (2007-04-13)
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