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Beta-catenin Current Events | Beta-catenin News
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What's the role of beta-catenin in colorectal cancers?
Beta-catenin, a central molecule of the Wnt-signaling pathway was previously known to involve in the tumorigenesis of various gastrointestinal cancers such as gastric cancer and colon cancer. view more (2008-11-03)
Researchers Reveal Possibility of Separating Anticancer Properties of Vitamin D
At the right dose, vitamin D is important for bone development and may help protect against the development of several cancers, particularly colorectal cancer. view more (2006-03-20)
'Hub' of fear memory formation identified in brain cells
A protein required for the earliest steps in embryonic development also plays a key role in solidifying fear memories in the brains of adult animals, scientists have revealed. An apparent "hub" for changes in the connections between brain cells, beta-catenin could be a potential target for drugs to enhance or interfere with memory... view more... (2008-09-29)
Heart regenerates after infarction -- first trials with mice
Up until today scientists assumed that the adult heart is unable to regenerate. Now, researchers and cardiologists from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and the Charité - Universitätsmedizin Berlin (Germany) have been able to show that this dogma no longer holds true. view more (2008-12-12)
Lithium and bone healing
Researchers have described a novel molecular pathway that may have a critical role in bone healing and have suggested that lithium, which affects this pathway, has the potential to improve fracture healing. view more (2007-07-31)
Researchers identify cancer-causing gene in many colon cancers
Demonstrating that despite the large number of cancer-causing genes already identified, many more remain to be found, scientists at Dana-Farber Cancer Institute have linked a previously unsuspected gene, CDK8, to colon cancer. view more (2008-09-15)
Wnt signalling protein Dishevelled acts in the nucleus, not just in the cytoplasm
Researchers have identified that Dishevelled doesn't only function in the cytoplasm and at the cell membrane - it must also pass into the nucleus. A study published today in Journal of Biology reveals that Dishevelled, a key player in the Wnt/beta-catenin signalling pathway, has to be localised in the nucleus to perform a key aspect of its... view more... (2005-02-11)
Analysis of alcoholics' brains suggests treatment target
An analysis of brain tissue samples from chronic alcoholics reveals changes that occur at the molecular level in alcohol abuse - and suggests a potential treatment target, according to researchers from Wake Forest University School of Medicine. view more (2008-05-05)
A surprise 'spark' for pre-cancerous colon polyps
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah studied the events leading to colon cancer and found that an unexpected protein serves as the "spark" that triggers formation of colon polyps, the precursors to cancerous tumors. view more (2009-05-15)
A gene for metastasis
Colorectal cancer is one of the most prevalent cancers in the Western world. The tumor starts off as a polyp but then turns into an invasive and violent cancer, which often spreads to the liver. view more (2007-08-28)
Scientists uncover indicator that warns leukemia is progressing to more dangerous form
Scientists at the Moores Cancer Center at the University of California, San Diego, Stanford University School of Medicine and other centers have identified a mechanism by which a chronic form of leukemia can progress into a deadlier stage of the disease. view more (2009-02-17)
Enzyme eliminated by cancer cells holds promise for cancer treatment
An enzyme that cancer cells eliminate, apparently so they can keep proliferating, may hold clues to more targeted, effective cancer treatment, scientists say. view more (2007-07-19)
Building the blood-brain barrier
Construction of the brain's border fence is supervised by Wnt/b-catenin signaling, report Liebner et al. in The Journal of Cell Biology. view more (2008-10-27)
Lost in the labyrinth
Blood cells have limited lifespans, which means that they must be continually replaced by calling up reserves, and turning these into the blood cell types needed by the body. view more (2006-09-05)
Tiny protein provokes healthy bonding between cells
In human relationships, a certain "spark" often governs whether we prefer one person to another, and critical first impressions can occur within seconds. A team lead by Johns Hopkins researchers has found that cell-to-cell "friendships" operate in much the same way and that dysfunctional bonding is linked to the spread of... view more... (2008-11-26)
Omega-3 fatty acids inhibit growth of liver cancer cells
Two new studies by a University of Pittsburgh research team suggest that omega-3 fatty acids-substances that are found in high concentrations in fish oils and certain seeds and nuts-significantly inhibit the growth of liver cancer cells. view more (2006-04-03)
T-beta-RIII joins the fight against breast cancer
Although the soluble factor TGF-beta has been shown to suppress the growth of tumor cells in the early stages of breast cancer, high levels of TGF-beta during the later stages of the disease are associated with a poor outcome. view more (2006-12-08)
High-dose Interferon Beta-1B On Alternate Days Could Offer Increased Clinical Benefit For People With Multiple Sclerosis (p 1453)
A study published in this week's issue of THE LANCET suggests that high-dose interferon beta-1b administered every other day is more effective than interferon beta-1a once a week for people with multiple sclerosis (MS). There are three interferon beta therapies known to be effective in reducing MS symptoms: interferon beta-1a 30 mcg administered... view more... (2002-04-24)
Tumors stopped from spreading to new sites
For several types of cancer, persistently high levels of the soluble factor TGF-beta in the blood after surgery, chemotherapy, or radiation therapy correlate with increased risk of early metastasis and a poor prognosis. view more (2007-04-06)
Stem cell research uncovers mechanism for type 2 diabetes
Taking clues from their stem cell research, investigators at the University of California San Diego (UC San Diego) and Burnham Institute for Medical Research (Burnham) have discovered that a signaling pathway involved in normal pancreatic development is also associated with type 2 diabetes. view more (2009-02-13)
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