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Further evidence showing treatment benefits of beta interferon for multiple sclerosis (pp 1463, 1489)
Results of a European study in this week's issue of THE LANCET provide further evidence that patients with early symptoms of multiple sclerosis given a weekly injection with interferon beta are less likely to progress to full clinical disease after two years follow-up. The study showed that the drug reduced patients' loss of brain tissue compared... view more... (2004-10-20)
Atrial fibrillation linked to increased hospitalization in heart failure patients
Patients with atrial fibrillation, common in those with advanced chronic heart failure, have an increased risk of hospitalization due to heart failure. view more (2009-07-07)
Test quickly assesses whether Alzheimer's drugs are hitting their target
A test developed by physician-scientists at Washington University School of Medicine in St. Louis may help assess more quickly the ability of Alzheimer's drugs to affect one of the possible underlying causes of Alzheimer's disease in humans, accelerating the development of new treatments. view more (2009-04-10)
Joslin researchers uncover potential role of leptin in diabetes
A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion. view more (2007-10-02)
Vaccine slows progression of skeletal muscle disorder
A potential vaccine for Alzheimer's disease also has been shown in mice to slow the weakening of muscles associated with inclusion body myositis, a disorder that affects the elderly. view more (2009-05-14)
New target for heart failure therapy identified
A novel signaling pathway plays a significant role in the production of aldosterone, a hormone that promotes heart failure after a myocardial infarction, according to a study conducted by Thomas Jefferson University researchers. view more (2009-03-17)
Inflammation may trigger Alzheimer's disease, Saint Louis University findings suggest
The anti-inflammatory drug indomethacin could hold promise as a treatment for Alzheimer's disease, says a Saint Louis University doctor and researcher. view more (2009-07-09)
Women at risk from vitamin A deficiency
Almost half of UK women could be suffering from a lack of vitamin A due to a previously undiscovered genetic variation, scientists at Newcastle University have found. view more (2009-11-18)
Joslin study indicates insulin receptors play a critical role in promoting islet growth
A new Joslin-led study has identified the insulin receptor as an important protein that promotes islet cell growth in mice whose bodies are unable to use insulin properly, or are insulin resistant, a precursor to type 2 diabetes. view more (2007-04-03)
Early stage colon cancer characterized by inactivation of gatekeeper gene
The absence or inactivation of the RUNX3 gatekeeper gene paves the way for the growth and development of colon cancer, Singapore scientists report in the Sept. issue of the journal Cancer Cell. Previous studies have shown that RUNX3 plays a role in gastric, breast, lung and bladder cancers. view more (2008-09-10)
Two-faced protein can stop metastasis or promote it, researchers say
A protein known to be a key component of the glue that holds cells together also is involved in breaking them apart and promoting their movement when tumors begin to spread to other parts of the body, researchers at Mayo Clinic have found. view more (2006-09-19)
Device Protects Transplanted Pancreatic Cells from the Immune System
Scientists at Burnham Institute for Medical Research (Burnham) and the University of California San Diego (UC San Diego) School of Medicine have demonstrated in mice that transplanted pancreatic precursor cells are protected from the immune system when encapsulated in polytetrafluorethylene (PTFE). view more (2009-04-10)
Gladstone scientists uncover potential mechanism of memory loss in Alzheimer's disease
Researchers at the Gladstone Institute of Neurological Disease (GIND) and Baylor College of Medicine have discovered a mechanism by which the protein Amyloid-beta(AB) may impair neurological functions in Alzheimer's disease. view more (2007-09-06)
New marker for Alzheimer's discovered
Gothenburg researchers have discovered a previously unknown substance in spinal fluid that can be used to diagnose Alzheimer's disease. view more (2009-09-15)
Researchers get closer to preventing Alzheimer's disease
A recent study directed by Mount Sinai School of Medicine identifies a faulty molecule in the brain found in cases of mild cognitive impairment (MCI). view more (2006-07-06)
Researchers close in on origins of main ingredient of Alzheimer's plaques
The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at Washington University School of Medicine in St. Louis have learned. view more (2008-04-10)
Yeast model shows promise as Alzheimer's test
A century ago this month, German psychiatrist Alois Alzheimer formally described characteristics of the neurodegenerative disease which ultimately came to bear his name. view more (2006-11-20)
Pumpkin: A fairytale end to insulin injections?
Compounds found in pumpkin could potentially replace or at least drastically reduce the daily insulin injections that so many diabetics currently have to endure. view more (2007-07-09)
Scientists develop fungus-fighting vaccine
group of scientists in Italy have developed a vaccine with the potential to protect against fungal pathogens that commonly infect humans, according to a study by Torosantucci and colleagues in the September 5 issue of The Journal of Experimental Medicine. view more (2005-09-06)
Purdue findings reveal possible Alzheimer's link to brain organ
Researchers have discovered that an organ in the brain called the choroid plexus apparently plays a critical role in preventing the accumulation of a protein associated with Alzheimer's disease. view more (2006-03-22)
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