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Genetic differences may help explain response to multiple sclerosis treatment
By comparing the DNA of patients with multiple sclerosis whose symptoms are reduced by interferon beta therapy to the DNA of those who continue to experience relapses, researchers may have identified important genetic differences between the two. view more (2008-01-15)
NIAID scientists identify new cellular receptor for HIV
A cellular protein that helps guide immune cells to the gut has been newly identified as a target of HIV when the virus begins its assault on the body's immune system, according to researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). view more (2008-02-11)
Seeing Alzheimer's amyloids
In an important step toward demystifying the role protein clumps play in the development of neurodegenerative disease, researchers have created a stunning three-dimensional picture of an Alzheimer's peptide aggregate using electron microscopy. view more (2008-05-13)
Penn study points to new direction for pancreas cell regeneration
Replacing faulty or missing cells with new insulin-making cells has been the object of diabetes research for the last decade. Past studies in tissue culture have suggested that one type of pancreas cell could be coaxed to transform into insulin-producing islet cells. view more (2007-04-04)
Alzheimer's disease drug treats traumatic brain injury, report GUMC researchers
The destructive cellular pathways activated in Alzheimer's disease are also triggered following traumatic brain injury, say researchers from Georgetown University Medical Center (GUMC). view more (2009-07-13)
'Godmother' ant uses Mob tactics to rub out rivals
Researchers at the University of Sheffield and the University of Keele have discovered that Dinoponera quadriceps ants, known as Dinosaur ants, and the Mafia have something in common. Both have dominant leaders who give rivals a "kiss of death", as a signal for their 'mob' to punish the offender. The alpha female in a colony of Dinosaur... view more... (2002-09-02)
Prenatal Diagnosis Could Aid Treatment Of Beta Thalassaemia (pp 6, 41)
Authors of a research letter in this week's issue of THE LANCET highlight how prenatal testing could identify fetuses with appropriate tissue for treating beta thalassaemia in their older siblings. Prenatal testing could also identify fetuses who will develop beta thalassaemia and who could be treated with bone-marrow transplantation from a family... view more... (2003-07-02)
Alzheimer's vaccine clears plaque but has little effect on learning and memory impairment
A promising vaccine being tested for Alzheimer's disease does what it is designed to do - clear beta-amyloid plaques from the brain - but it does not seem to help restore lost learning and memory abilities, according to a University of California, Irvine study. view more (2008-04-07)
Moderate use averts failure of type 2 diabetes drugs in animal model
Drugs widely used to treat type 2 diabetes may be more likely to keep working if they are used in moderation, researchers at Washington University School of Medicine in St. Louis have found in a study using an animal model. view more (2008-10-28)
Study outlines how stroke, head injury can increase risk of Alzheimer's disease
Researchers from the MassGeneral Institute for Neurodegenerative Disorders (MGH-MIND) have discovered how the death of brain cells caused by a stroke or head injury may cause generation of amyloid-beta protein - the key component of senile plaques seen in the brains of patients with Alzheimer's disease. view more (2007-06-07)
Counselling can increase fruit and vegetable intake
Behavioural counselling can increase consumption of fruit and vegetables among deprived adults, finds a study in this week's BMJ. Researchers identified 271 patients, aged 18-70 years, from a health centre in a deprived, ethnically mixed inner city area. Patients were randomly assigned to two groups. One group received behavioural counselling... view more... (2003-04-15)
Vitamin D, curcumin may help clear amyloid plaques found in Alzheimer's disease
UCLA scientists and colleagues from UC Riverside and the Human BioMolecular Research Institute have found that a form of vitamin D, together with a chemical found in turmeric spice called curcumin, may help stimulate the immune system to clear the brain of amyloid beta, which forms the plaques considered the hallmark of Alzheimer's disease. view more (2009-07-16)
UAB Study Reveals Bone Coupling Factor Key to Skeletal Health
Researchers at the University of Alabama at Birmingham (UAB) have discovered a molecular coupling factor that helps bones grow and remodel themselves to stay strong, a finding that could lead to better bone-building therapies and new osteoporosis drugs, the researchers said view more (2009-07-08)
How to grow muscle cells in a dish
Smooth muscle cells (SMCs) are a crucial cellular component of many parts of the body, including blood vessels, the intestines, and the lungs. view more (2006-11-10)
The anti-diabetic effects of sodium tungstate revealed
The molecular mechanisms of tungstate activity in diabetes have been uncovered. Researchers writing in the open access journal BMC Genomics have identified the pathways through which sodium tungstate improves pancreatic function and beta cell proliferation. view more (2009-08-28)
'Polypill' improves survival rates for heart disease sufferers, says University study
A 'polypill' made up of a combination of drugs could extend the lives of thousands of patients with coronary heart disease, say researchers at The University of Nottingham. view more (2005-05-09)
HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection
Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress... view more... (2009-03-26)
Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
Vitamins C and E and beta carotene, either individually or in combination, do not appear to reduce the risk of cardiovascular events or death among women at high risk for heart disease. view more (2007-08-14)
Potential Alzheimer's disease drug target identified by UC San Diego researcher
In findings with the potential to provide a therapy for Alzheimer's disease patients where none now exist, a researcher at the University of California, San Diego and colleagues have demonstrated in mice a way to reduce the overproduction of a peptide associated with the disease. view more (2008-03-17)
Common beta-agonist inhalers more than double death rate in COPD patients, Cornell and Stanford scientists assert
A new analysis that compares two common inhalers for patients suffering from chronic obstructive pulmonary disease (COPD) finds that one reduces respiratory-related hospitalizations and respiratory deaths, but the other — which is prescribed in the majority of cases — increases respiratory deaths. view more (2006-07-10)
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