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Pumpkin: A fairytale end to insulin injections?
Compounds found in pumpkin could potentially replace or at least drastically reduce the daily insulin injections that so many diabetics currently have to endure. view more (2007-07-09)
Treatment-induced growth factor causes cancer progression
In advanced cancer, anti-tumor therapies often work only partially or not at all, and tumors progress following treatment. view more (2007-04-06)
CHEO RI study uses sophisticated genetic engineering to improve insulin-producing beta cells
One of the biggest mysteries about diabetes is why specialized cells in the pancreas stop secreting insulin, which the body needs in order to store glucose from food. view more (2009-10-08)
Discovery of new signal pathway important to diabetes research
Scientists at Karolinska Institutet in Sweden and Miami University have discovered that cells in the pancreas cooperate - signal - in a way hitherto unknown. The discovery can eventually be of significance to the treatment of diabetes. view more (2008-06-05)
Joslin study indicates insulin receptors play a critical role in promoting islet growth
A new Joslin-led study has identified the insulin receptor as an important protein that promotes islet cell growth in mice whose bodies are unable to use insulin properly, or are insulin resistant, a precursor to type 2 diabetes. view more (2007-04-03)
Joslin-led study uncovers role of appetite hormone MCH in insulin production
A new Joslin Diabetes Center-led study has shown conclusively that a neuropeptide, melanin concentrating hormone (MCH), found in the brain and known for its role in increasing appetite in people, plays a role in the growth of insulin-producing beta cells and the secretion of insulin. view more (2007-01-29)
Compounds that trigger beta cell replication identified by JDRF funded researchers
Researchers at the Genomics Institute of the Novartis Research Foundation (GNF) have identified a set of compounds that can trigger the proliferation of insulin-producing cells in the pancreas, using sophisticated high-throughput screening techniques. view more (2009-02-26)
Mouse model developed at UT Southwestern mimics hyperglycemia, aids in diabetes research
UT Southwestern Medical Center researchers have genetically engineered a laboratory mouse in which pancreatic beta cells can regenerate after being induced to die. The new animal model's regenerative ability may provide future insights into improved treatments of diabetes, which affects millions of Americans. view more (2008-06-02)
Penn study points to new direction for pancreas cell regeneration
Replacing faulty or missing cells with new insulin-making cells has been the object of diabetes research for the last decade. Past studies in tissue culture have suggested that one type of pancreas cell could be coaxed to transform into insulin-producing islet cells. view more (2007-04-04)
Government money for multiple sclerosis patients could be better spent
The National Institute for Clinical Excellence (NICE) has announced that neither interferon beta nor glatiramer can be recommended for multiple sclerosis in the NHS. However, the UK government plans to make these drugs available through a risk sharing scheme, despite limited evidence of clinical and cost effectiveness. Researchers in this week's... view more... (2003-02-12)
Researchers close in on origins of main ingredient of Alzheimer's plaques
The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at Washington University School of Medicine in St. Louis have learned. view more (2008-04-10)
Detection Of Antibodies Could Identify MS Patients Who Do Not Respond Well To Interferon Beta (P1184)
Danish research published in this week's issue of THE LANCET highlights how the detection of antibodies to interferon beta-the first choice treatment for multiple sclerosis patients-could be important in identifying patients who do not respond well to interferon beta, with implications for the provision of alternative drug therapy. Interferon beta... view more... (2003-10-08)
Joslin researchers uncover potential role of leptin in diabetes
A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion. view more (2007-10-02)
Enzyme may be a key to Alzheimer's-related cell death
A Purdue University researcher has discovered that the amount of an enzyme present in neurons can affect the mechanism thought to cause cell death in Alzheimer's disease patients and may have applications for other diseases such as stroke and heart attack. view more (2009-10-08)
Joslin-led study reveals findings on how insulin-producing beta cells grow and function
Joslin-led study reveals findings on how insulin-producing beta cells grow and function view more (2006-04-24)
Circulating fats kill transplanted pancreas cells, study shows
Dietary restrictions or other strategies that limit fat formation might make pancreatic cell transplants more effective, UT Southwestern Medical Center researchers report. view more (2007-08-28)
Anesthesia and Alzheimer's
In studies of human brain cells, the widely-used anesthetic desflurane does not contribute to increased production of amyloid-beta protein; however, when combined with low oxygen conditions, it can produce more of this Alzheimer's associated protein. view more (2008-04-28)
Anaemia Treatment Could Worsen Cancer Prognosis (p1255)
Results of a European study in this week's issue of THE LANCET cast doubt over the value of treating anaemia with erythropoietin (epoetin beta) among patients who have cancer. Results of the study show that anaemic patients fare better in terms of reduced cancer progression and increased survival if their anaemia is not treated around the time of... view more... (2003-10-15)
Heart regenerates after infarction -- first trials with mice
Up until today scientists assumed that the adult heart is unable to regenerate. Now, researchers and cardiologists from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and the Charité - Universitätsmedizin Berlin (Germany) have been able to show that this dogma no longer holds true. view more (2008-12-12)
Increased sensitivity to nerve signals keeps diabetes at bay
Nerve signals relayed directly to the pancreas after eating a meal play a critical role in normal blood sugar control. view more (2006-06-07)
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