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Rapid changes in key Alzheimer's protein described in humans
For the first time, researchers have described hour-by-hour changes in the amount of amyloid beta, a protein that is believed to play a key role in Alzheimer's disease, in the human brain. view more (2008-08-29)
Team reveals molecular mechanism underlying a form of diabetes
By investigating a rare and severe form of diabetes in children, University of Iowa researchers have discovered a new molecular mechanism that regulates specialized pancreatic cells and insulin secretion. view more (2009-09-09)
UCLA scientists identify how immune cells may help predict Alzheimer's risk
What if you could test your risk for Alzheimer's disease much like your cholesterol levels - through a simple blood test? view more (2009-07-14)
Beta-carotene assoc. with higher risk of some cancers in women smokers but not nonsmokers
A new study of French women has found that high beta-carotene intake-through a combination of diet or supplementation-is associated with a higher risk of tobacco-related cancers in smokers, but the risk of these cancers decreases with increasing beta-carotene intake in nonsmokers. view more (2005-09-21)
New study reveals signaling pathways required for expansion of pancreas stem cells
IDDM, which used to be referred to as Type 1 diabetes, results from selective destruction of insulin-producing pancreatic islet beta cells by the body's immune system. view more (2006-05-17)
Mayo Clinic researchers find agents that speed up destruction of proteins linked to Alzheimer's
Taking a new approach to the treatment and prevention of Alzheimer's disease, a research team led by investigators at the Mayo Clinic campus in Florida has shown that druglike compounds can speed up destruction of the amyloid beta (A-beta) proteins that form plaque in the brains of patients with the disorder. view more (2009-04-22)
U.Va. Scientists Identify 'Missing Link' in Process Leading to Alzheimer's Disease
Scientists at the University of Virginia have identified what appears to be a major missing link in the process that destroys nerve cells in Alzheimer's disease, an incurable disease that slowly destroys memory and cognitive abilities. view more (2007-02-08)
New cause of critical illness hypeglycemia identified
The endocrinologic basis of pediatric critical illness hypergylcemia (CIH) differs depending on the disease processes. Researchers writing in BioMed Central's open access journal Critical Care describe how both peripheral insulin resistance and primary beta-cell dysfunction can cause CIH in children. view more (2009-02-26)
Inhibitor of novel cancer target, LPAAT-beta, demonstrates selective anti-cancer effects in animal cancer models
Frankfurt, Germany: In a plenary session at the Symposium on Molecular Targets and Cancer Therapeutics, Dr Jack W. Singer, M.D. and Research Program Chairman of Cell Therapeutics, Inc. (CTI) today (Thursday 21 November) presented data from preclinical studies on a novel cancer target LPAAT-beta[1] in cultured cells and in preliminary animal... view more... (2002-11-17)
The Definitive Beta-blocker For Heart Failure? (pp 2, 7, 14)
Results of a European study in this week's issue of THE LANCET suggest that the beta-blocker carvedilol offers substantial survival benefit compared with another widely-used beta blocker for the treatment of chronic heart failure. Beta blockers reduce death in patients who are also taking diuretics and ACE inhibitors for chronic heart failure. In... view more... (2003-07-02)
Lost in the labyrinth
Blood cells have limited lifespans, which means that they must be continually replaced by calling up reserves, and turning these into the blood cell types needed by the body. view more (2006-09-05)
Wnt signalling protein Dishevelled acts in the nucleus, not just in the cytoplasm
Researchers have identified that Dishevelled doesn't only function in the cytoplasm and at the cell membrane - it must also pass into the nucleus. A study published today in Journal of Biology reveals that Dishevelled, a key player in the Wnt/beta-catenin signalling pathway, has to be localised in the nucleus to perform a key aspect of its... view more... (2005-02-11)
Research yields potential target for cancer, wound healing and fibrosis
Research conducted by Allison Berrier, PhD, Assistant Professor of Oral and Craniofacial Biology at the LSU Health Sciences Center New Orleans School of Dentistry, and colleagues, provides insights that may help scientists design novel approaches to control wound healing and fight diseases such as cancer and fibrosis. view more (2009-03-19)
Further evidence showing treatment benefits of beta interferon for multiple sclerosis (pp 1463, 1489)
Results of a European study in this week's issue of THE LANCET provide further evidence that patients with early symptoms of multiple sclerosis given a weekly injection with interferon beta are less likely to progress to full clinical disease after two years follow-up. The study showed that the drug reduced patients' loss of brain tissue compared... view more... (2004-10-20)
Atrial fibrillation linked to increased hospitalization in heart failure patients
Patients with atrial fibrillation, common in those with advanced chronic heart failure, have an increased risk of hospitalization due to heart failure. view more (2009-07-07)
Interesting lead in the treatment of Ewing`s sarcoma
Research scientists at INSERM, CNRS and the Institut Curie, in collaboration with physicians, have used a mouse model to demonstrate the efficacy of an innovative therapeutic approach to Ewing`s sarcoma: the combination of human interferon (alpha or beta) and a common anti-tumor agent, ifosfamide. Their results were published in the November 2002... view more... (2002-10-31)
Beating the aging process naturally
The fight against aging has received a scientific boost thanks to an innovative study done in part by a University of Alberta spin-off company-research that dispels a hard-held belief about the natural ingredient, beta glucan. view more (2005-09-30)
Gas-blockers might slow down Alzheimer's disease
A noxious gas speeds up brain degeneration in Alzheimer's disease, according to a study in the November 7 issue of The Journal of Experimental Medicine. view more (2005-10-31)
Substance in tree bark could lead to new lung-cancer treatment
Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer. view more (2007-06-26)
Alzheimer's-associated enzyme can disrupt neural activity in the brain
An enzyme involved in the formation of the amyloid-beta protein associated with Alzheimer's disease can also alter the mechanism by which signals are transmitted between brain cells, the disruption of which can cause seizures. view more (2007-06-18)
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