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Analysis of millions of US births shows association between birth defects and preterm birth
Babies born preterm were more than twice as likely to have major birth defects as full-term infants, according to a new analysis of nearly 7 million U.S. live births published online this week in the Springer journal Maternal and Child Health Journal.   view more (2008-05-21)

Sexually transmitted disease, urinary tract infections may be bad combination for birth defect Chances of gastroschisis increase fourf
Women who reported having both a sexually transmitted disease (STD) and urinary tract infection (UTI) just before or during early pregnancy were four times more likely to have babies with gastroschisis-a severe birth defect in which infants are born with their intestines and other internal organs... view more (2008-06-23)

New data reveal pregnancies exposed to accutane despite risk management program
Despite a mandatory program designed to prevent pregnant women from being exposed to the anti-acne medication Accutane and similar medications containing isotretinoin (a known teratogen or birth defect-causing agent), 122 pregnancies were exposed during the first year of the program, known as... view more (2007-08-01)

National statistics for 18 major birth defects released
Cleft lip is a treatable birth defect, but for the families of the estimated 6,800 U.S. infants born with one, it's a heartbreaking experience - not only because of the associated health problems, but because friends and family may ignore the condition or because of social stigma associated with... view more (2006-01-06)

Oregon researchers discover a mechanism leading to cleft palate
By creating a genetic mutation in zebrafish, University of Oregon scientists say they've discovered a previously unknown mechanism for cleft palate, a common birth defect in humans that has challenged medical professionals for centuries.   view more (2008-02-12)

SSRI antidepressants do not pose major birth defect risk
Researchers from Boston University's Slone Epidemiology Center have found that certain selective serotonin reuptake inhibitors antidepressants do not appear to increase the risk for most kinds of birth defects.   view more (2007-06-28)

Regulatory T cells require WASp if they are to prevent self-destruction
In humans, mutation of the gene encoding a protein known as WASp leads to susceptibility to infections and systemic autoimmunity.   view more (2007-01-12)

UT-Houston's Northrup and Colleagues Uncover Genetic Link to Spina Bifida
Researchers at The University of Texas Medical School at Houston have discovered an association between genes regulating glucose metabolism and spina bifida. The decade-long study looked at more than 1,500 DNA samples from parents and their children with that birth defect.   view more (2007-12-19)

Size at birth linked with risk of breast cancer in women under 50
A study in the BMJ this week finds an association between size at birth and risk of pre-menopausal breast cancer.   view more (2003-01-29)

Is tap water safe for expectant mothers?
Drinking water disinfected by chlorine while pregnant may increase the risk of having children with heart problems, cleft palate or major brain defects, according to a study published today in BioMed Central's open access journal Environmental Health.   view more (2008-06-03)

Cleft palate in fetal mice prevented by treating
Mice engineered to have cleft palates can be rescued in utero by injecting the mothers with a small molecule to correct the defect, say scientists at the Stanford University School of Medicine and Lucile Packard Children's Hospital.   view more (2007-02-12)

Bigger babies at greater risk of pre-menopausal breast cancer
Women who had a greater birth size have a significantly higher risk than others of developing pre-menopausal breast cancer, according to a study carried out by the London School of Hygiene & Tropical Medicine. The study, reported in the British Medical Journal today, looked at 5,000 women born... view more (2003-01-29)

Birth weight and social class linked to educational achievement
Birth weight and social class at birth have a strong influence on cognitive (mental) function in children, say researchers in this week's BMJ. The study involved 10,845 males and females born during 3-9 March 1958 in England, Scotland, and Wales. The team investigated the combined effect of birth... view more (2002-08-07)

Effect of microstructure on the coercivity of HDDR Nd-Fe-B permanent magnetic alloy
The School of Physics, Shandong University, has shown that the coercivity mechanism of HDDR Nd-Fe-B permanent magnetic alloy is greatly related to its microstructure defect at the grain boundary. The investigation can provide a clear understanding of coercivity mechanism, and hence will be reported... view more (2008-07-24)

Change in gene may be underlying molecular defect in some colorectal cancers, study suggests
Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer.   view more (2005-09-21)

Slight increased risk of major birth defects associated with IVF
Babies conceived through in vitro fertilization (IVF), a method of assisted reproduction, have a slightly increased risk of major birth defects, such as heart or muscle and skeletal defects, compared to babies conceived naturally.   view more (2005-12-01)

Birth weight may be linked to arthritis in later life
The cause of rheumatoid arthritis is unknown, but researchers in this week’s BMJ suggest that some factors relating to the period shortly before and after birth (perinatal factors) may be implicated in the development of the disease in later life.   view more (2003-05-14)

Human reproductive rates follow biological scaling rules
In nations with high per capita energy consumption, women have fewer children. This phenomenon is an unexpected consequence of the biological scaling relationship between metabolism and reproductive rate: larger species of mammals have higher metabolism but lower birth rates. In the April 2003... view more (2003-04-08)

Commonly used drug may prevent fetal alcohol syndrome
Fetal alcohol syndrome (FAS) is often called the number one preventable birth defect.   view more (2006-02-21)

Low intake of milk in pregnancy associated with decreased birth weight
Women increasingly self-restrict milk intake during pregnancy, for a variety of reasons. Does this have an effect on their infants' birth weight?   view more (2006-04-25)

Jefferson researchers want to learn if heart defect 'at heart' of some migraines
Researchers of the heart and headaches at Thomas Jefferson University Hospital are combining efforts to determine if a common heart defect may be the cause of some forms of migraine headaches.   view more (2007-04-23)

Twins have similar school performance to single-born children
Twins have similar academic performance to single-born children, finds a large Danish study published online by the BMJ today.   view more (2006-09-29)

Temperature at birth linked to health later in life
Cold outdoor temperature at birth is associated with increased coronary heart disease and insulin resistance, high cholesterol levels, and poor lung function in later life, suggests a study in Heart. This link was strongest among those from the lowest social and economic classes. Researchers... view more (2004-03-09)

Low birth weight of a baby entails risks for the baby's father
Parents whose children are born with a low birth weight run greater risk of dying of cardiovascular diseases. Even the fathers are at greater risk. These findings are published in a new report by Karolinska Institutet. The report shows that genetic factors affect both birth weight and the risk of... view more (2005-06-29)

New method for predicting risk of emergency caesarean section after a previous caesarean
A paper published in PLoS Medicine provides a novel method for estimating the risk of emergency caesarean section after a previous caesarean section.   view more (2005-09-13)

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