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Analysis of millions of US births shows association between birth defects and preterm birth
Babies born preterm were more than twice as likely to have major birth defects as full-term infants, according to a new analysis of nearly 7 million U.S. live births published online this week in the Springer journal Maternal and Child Health Journal.   view more (2008-05-21)

Sexually transmitted disease, urinary tract infections may be bad combination for birth defect Chances of gastroschisis increase fourf
Women who reported having both a sexually transmitted disease (STD) and urinary tract infection (UTI) just before or during early pregnancy were four times more likely to have babies with gastroschisis-a severe birth defect in which infants are born with their intestines and other internal organs outside the abdomen, University of Utah researchers... view more... (2008-06-23)

New data reveal pregnancies exposed to accutane despite risk management program
Despite a mandatory program designed to prevent pregnant women from being exposed to the anti-acne medication Accutane and similar medications containing isotretinoin (a known teratogen or birth defect-causing agent), 122 pregnancies were exposed during the first year of the program, known as iPledge, a report revealed.   view more (2007-08-01)

Time of conception linked to birth defects in United States
A study published in the April 2009 issue of the medical journal Acta Pædiatrica is the first to report that birth defect rates in the United States were highest for women conceiving in the spring and summer. The researchers also found that this period of increase risk correlated with increased levels of pesticides in surface water across the... view more... (2009-03-31)

National statistics for 18 major birth defects released
Cleft lip is a treatable birth defect, but for the families of the estimated 6,800 U.S. infants born with one, it's a heartbreaking experience - not only because of the associated health problems, but because friends and family may ignore the condition or because of social stigma associated with facial defects.   view more (2006-01-06)

Oregon researchers discover a mechanism leading to cleft palate
By creating a genetic mutation in zebrafish, University of Oregon scientists say they've discovered a previously unknown mechanism for cleft palate, a common birth defect in humans that has challenged medical professionals for centuries.   view more (2008-02-12)

SSRI antidepressants do not pose major birth defect risk
Researchers from Boston University's Slone Epidemiology Center have found that certain selective serotonin reuptake inhibitors antidepressants do not appear to increase the risk for most kinds of birth defects.   view more (2007-06-28)

Regulatory T cells require WASp if they are to prevent self-destruction
In humans, mutation of the gene encoding a protein known as WASp leads to susceptibility to infections and systemic autoimmunity.   view more (2007-01-12)

UT-Houston's Northrup and Colleagues Uncover Genetic Link to Spina Bifida
Researchers at The University of Texas Medical School at Houston have discovered an association between genes regulating glucose metabolism and spina bifida. The decade-long study looked at more than 1,500 DNA samples from parents and their children with that birth defect.   view more (2007-12-19)

Clue to genetic cause of fatal birth defect
A novel enzyme may play a major role in anencephaly, offering hope for a genetic test or even therapy for the rare fatal birth defect in which the brain fails to develop, according to a study from researchers at the University of Illinois at Chicago College of Medicine.   view more (2008-10-10)

Local health investigation sheds light on gastroschisis birth defect
Results of an investigation conducted by University of Nevada, Reno researchers, public health officials and area physicians published this week in the Archives of Pediatrics & Adolescent Medicine, indicate that Washoe County experienced a cluster of a particular birth defect, gastroschisis, during the period April 2007 - April 2008.   view more (2009-11-09)

Hairspray is linked to common genital birth defect, says study
Women who are exposed to hairspray in the workplace during pregnancy have more than double the risk of having a son with the genital birth defect hypospadias, according to a new study published today in the journal Environmental Health Perspectives.    view more (2008-11-24)

Size at birth linked with risk of breast cancer in women under 50
A study in the BMJ this week finds an association between size at birth and risk of pre-menopausal breast cancer.   view more (2003-01-29)

Is tap water safe for expectant mothers?
Drinking water disinfected by chlorine while pregnant may increase the risk of having children with heart problems, cleft palate or major brain defects, according to a study published today in BioMed Central's open access journal Environmental Health.   view more (2008-06-03)

Bigger babies at greater risk of pre-menopausal breast cancer
Women who had a greater birth size have a significantly higher risk than others of developing pre-menopausal breast cancer, according to a study carried out by the London School of Hygiene & Tropical Medicine. The study, reported in the British Medical Journal today, looked at 5,000 women born in Sweden during 1915-29, of which 63 had... view more... (2003-01-29)

Low levels of vitamin B12 may increase risk for neural tube defects
Children born to women who have low blood levels of vitamin B12 shortly before and after conception may have an increased risk of a neural tube defect, according to an analysis by researchers at the National Institutes of Health, Trinity College Dublin, and the Health Research Board of Ireland.   view more (2009-03-02)

Cleft palate in fetal mice prevented by treating
Mice engineered to have cleft palates can be rescued in utero by injecting the mothers with a small molecule to correct the defect, say scientists at the Stanford University School of Medicine and Lucile Packard Children's Hospital.   view more (2007-02-12)

Birth weight and social class linked to educational achievement
Birth weight and social class at birth have a strong influence on cognitive (mental) function in children, say researchers in this week's BMJ. The study involved 10,845 males and females born during 3-9 March 1958 in England, Scotland, and Wales. The team investigated the combined effect of birth weight and socioeconomic environment on cognitive... view more... (2002-08-07)

Preterm birth rate drops
The nation's preterm birth rate declined slightly in 2007 - a finding that the March of Dimes hopes will prove to be the start of a new trend in improved maternal and infant health.   view more (2009-03-19)

Effect of microstructure on the coercivity of HDDR Nd-Fe-B permanent magnetic alloy
The School of Physics, Shandong University, has shown that the coercivity mechanism of HDDR Nd-Fe-B permanent magnetic alloy is greatly related to its microstructure defect at the grain boundary. The investigation can provide a clear understanding of coercivity mechanism, and hence will be reported in Science in China Series G-Physics, Mechanism... view more... (2008-07-24)
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