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Birth Defects Current Events | Birth Defects News | 5

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Cholesterol could be key to treating fetal alcohol syndrome
Small amounts of alcohol can interfere with the growth of a fetus, but added cholesterol may help prevent a wide array of neurological and physical defects from alcohol exposure, according to a new study in laboratory fish.   view more (2007-03-09)

No drop in IQ seen after bypass for child heart surgery
The use of cardiopulmonary bypass does not cause short-term neurological problems in children and teenagers after surgery for less complex heart defects, according to pediatric researchers.   view more (2008-11-11)

Teenagers not at higher risk during first birth, but a second may lead to complications
Teenagers giving birth for the first time are not at increased risk of adverse pregnancy outcomes. However, those having second births run an almost threefold risk of premature delivery and stillbirth, concludes a study in this week's BMJ. Researchers at Glasgow University identified over 110,000 non-smoking women, aged between 15 and 29 years,... view more... (2001-08-29)

Very long or short intervals between pregnancies associated with increased poor perinatal outcomes
Intervals between pregnancies shorter than 18 months and longer than 59 months are associated with increased risk of low birth weight, preterm birth and small size for gestational age.   view more (2006-04-19)

New insights into neural tube defects
Environmental and genetic factors lead to neural tube defects in 1 in every 1,000 births and cause 1 in 20 of every spontaneous abortion. One cause of these defects is the failure of cells within the neural tube to migrate to the middle of the developing neural tube.   view more (2006-01-12)

'Bigger the baby, the better' axiom is incorrect
Dr Rachel Huxley, lead author of the paper and Acting Director of Nutrition and Lifestyle at The George Institute said, "Although there was support for a small association between birth weight and an individual's future risk of heart disease, the relationship is not as strong as earlier studies have suggested.   view more (2007-05-18)

Inflammatory bowel disease doubles risk of pregnancy complications
Inflammatory bowel disease roughly doubles the chances of pregnancy complications, reveals research published ahead of print in Gut.   view more (2006-12-21)

African-Americans at increased risk for earlier preterm births
Using data from over 700,000 births in Missouri from 1989 to 1997, researchers found that African American mothers were 3 times more likely than Caucasian mothers to deliver prematurely at 20-34 weeks and almost 4 times more likely to deliver extremely prematurely at 20-28 weeks.   view more (2007-02-12)

Brewing up potential anti-cancer drugs from green tea
Drinking green tea has a protective effect against some forms of cancer but drinking large amounts can increase the risk of birth defects such as spina bifida - according to previous epidemiological studies.   view more (2005-03-14)

Embryology Study Offers Clues to Birth Defects
Gregg Duester, Ph.D., professor of developmental biology at Burnham Institute for Medical Research (Burnham), along with Xianling Zhao, Ph.D., and colleagues, have clarified the role that retinoic acid plays in limb development.   view more (2009-06-10)

Babies conceived with medical assistance face high risk at birth
Babies born following medically assisted reproduction face a much higher risk of problems at birth and death during delivery, compared with babies conceived naturally, say researchers in this week's BMJ - though the outcome for twins is better. In births involving a single baby, infants fared worse than babies conceived without medical help in... view more... (2004-01-23)

Amoxicillin use during infancy may be linked to tooth enamel defects
Use of the antibiotic amoxicillin during infancy appears to be linked to tooth enamel defects in permanent teeth, according to a study in the October issue of Archives of Pediatrics and Adolescent Medicine, one of the JAMA/Archives journals.   view more (2005-10-04)

Kids with autism may have gene that causes muscle weakness
Some kids with autism may have a genetic defect that affects the muscles, according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12-19, 2008.   view more (2008-04-14)

Birth size is a marker of susceptibility to breast cancer later in life
Birth size, and in particular birth length, correlates with subsequent risk of breast cancer in adulthood, according to a new study published in PLoS Medicine by researchers at the London School of Hygiene and Tropical Medicine.   view more (2008-09-30)

Study sheds new light on link between birth weight, obesity, and childhood growth
Boys who are light at birth, but then grow rapidly during childhood, are more likely to be obese as adults, is just one of the findings from a large study in this week's BMJ. These potentially complex interrelationships may hold the key to effective preventive strategies. Tessa Parsons and colleagues used data collected from all children born in... view more... (2001-12-05)

Pulmonary hypertension in children may result from reduced activity of gene regulator
Too little activity by gene regulators called PPARs appears to be a major player in the irreversible lung damage that can occur in children with heart defects, researchers say.   view more (2009-03-06)

Newly found enzymes may play early role in cancer
Researchers have discovered two enzymes that, when combined, could be involved in the earliest stages of cancer. Manipulating these enzymes genetically might lead to targeted therapies aimed at slowing or preventing the onset of tumors.   view more (2008-12-29)

Small birthweight and premature births associated with higher risk of child abuse
Small birthweight and premature birth may be associated with a higher risk of child abuse and neglect, suggests research in the Journal of Epidemiology and Community Health.   view more (2006-03-15)

Progesterone therapy and preterm birth: More evidence helps identify women who can benefit
Two major studies published today in The New England Journal of Medicine can help doctors better identify pregnant women at risk for preterm delivery who can benefit from progesterone treatment, the March of Dimes Foundation said today.   view more (2007-08-02)

Study Suggests Link Between Down's Syndrome And Neural-tube Defects (pp 1316, 1331)
Authors of a study in this week's issue of THE LANCET highlight how infants born within families who have a high risk of neural-tube defects (NTD) could also be at an increased risk of Down's syndrome-and vice versa, suggesting an association between Down's syndrome and NTD. NTD are birth defects of the brain or spinal cord caused by abnormal... view more... (2003-04-16)
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