Blood-brain Barrier Current Events | Blood-brain Barrier News | 3
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Blocking toxic effects could make clot-buster safer
Since the introduction of the life-saving clot-busting drug tPA more than a decade ago, evidence has been accumulating that tPA (tissue-type plasminogen activator) can be a double-edged sword for a brain affected by stroke. view more (2009-01-23)
Vasectomy may put men at risk for type of dementia
Northwestern University researchers have discovered men with an unusual form of dementia have a higher rate of vasectomy than men the same age who are cognitively normal. view more (2007-02-13)
Study reveals new player in sepsis-associated acute respiratory distress syndrome
Every year, more than 200, 000 Americans die from sepsis, a severe illness caused by bacterial infection of the bloodstream. view more (2006-01-24)
Blood Pressure Drug Telmisartan Shows Powerful Activity Against Stroke
Telmisartan, a drug widely used to help control blood pressure, may have uniquely potent activity in preventing stroke, according to a new study conducted in an animal model. view more (2007-12-13)
Leaky blood vessels open up nerve cells to toxic assault in Lou Gehrig's disease
Leaky blood vessels that lose their ability to protect the spinal cord from toxins may play a role in the development of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, according to research published in the April issue of Nature Neuroscience. view more (2008-04-08)
Blame the brain for high blood pressure
The controversial idea that one cause of high blood pressure lies within the brain, and not the heart or blood vessels, has been put forward by scientists at the University of Bristol, UK, and is published this week in the journal Hypertension. view more (2007-04-16)
Smokers invite to test vaccine against nicotine addiction
UCSF's Habit Abatement Clinic is testing a vaccine that enlists help from the immune system to keep nicotine away from the brain. The vaccine is designed to help smokers quit and to limit the urge to start smoking again. view more (2006-06-12)
Small molecule inhibitor shows promise in trastuzumab-resistant metastatic breast cancer
Fox Chase Cancer Center researchers report that a combination of trastuzumab and neratinib (HKI-272) a novel small molecule inhibitor of the HER2 receptor (ErbB2) appears active in women with HER2-positive metastatic breast cancer who have progressed on previous trastuzumab based therapies. view more (2009-05-29)
Cedars-Sinai researchers discover treatment for deadly brain tumors and infections
In a study published in the March 15 issue of The Journal of Immunology, researchers at Board of Governors' Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have developed a way to overcome immune privilege in the brain to eradicate potentially deadly brain tumors such as glioblastoma multiforme and other types of brain... view more... (2006-03-27)
U-M researchers use nanoparticles to target brain cancer
Tiny particles one-billionth of a meter in size can be loaded with high concentrations of drugs designed to kill brain cancer. view more (2006-11-15)
Hybrid molecules show promise for exploring, treating Alzheimer's
One of the many mysteries of Alzheimer's disease is how protein-like snippets called amyloid-beta peptides, which clump together to form plaques in the brain, may cause cell death, leading to the disease's devastating symptoms of memory loss and other mental difficulties. view more (2009-11-05)
A brainy idea 25 years in the making
A discovery made 25 years ago about how the brain controls blood pressure regulation is only now being explored with the help of scientists from the Howard Florey Institute. view more (2007-10-04)
Potential new target for multiple sclerosis therapy
Researchers demonstrate both genetic and pharmaceutical evidence for the role of a protein called collagenase-2 in the development of multiple sclerosis (MS), providing a potential new way to combat this debilitating disease. view more (2008-03-31)
Holding Breath for Several Minutes Elevates Marker for Brain Damage
Divers who held their breath for several minutes had elevated levels of a protein that can signal brain damage, according to a new study from the Journal of Applied Physiology. view more (2009-08-04)
During exercise, the human brain shifts into high gear on 'alternative energy'
Alternative energy is all the rage in major media headlines, but for the human brain, this is old news. According to a study by researchers from Denmark and The Netherlands published in the October 2008 print issue of The FASEB Journal, the brain, just like muscles, works harder during strenuous exercise and is fueled by lactate, rather than... view more... (2008-10-01)
Molecule helps cells plug leaks following lung injury
Researchers at the University of Illinois at Chicago College of Medicine have identified a molecule that plays a critical role in the recovery of lung tissue following severe injury. view more (2006-09-15)
Monitoring of blood flow to the brain could prevent brain damage
University of Southampton engineers believe that monitoring blood flow to the brains of head injury patients could potentially reduce the incidence of brain damage and long-term disability, and are developing methods of using ultrasound to do this. With many years experience in studying the rise and fall of pressure inside the heads of patients... view more... (2003-04-30)
U of MN researchers identify new cord blood stem cell
Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells. view more (2006-02-14)
New UW study offers strategy for treatment of fatal nervous system disorder
Working with mice, University of Wisconsin-Madison researchers have developed the basis for a therapeutic strategy that could provide hope for children afflicted with Krabbe's disease, a fatal nervous system disorder. view more (2005-12-13)
Blood thinning drug linked to increased bleeding in brain
A new study shows that people who take the commonly used blood thinning drug warfarin may have larger amounts of bleeding in the brain and increased risk of death if they suffer a hemorrhagic stroke. view more (2008-09-30)
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