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Novel laboratory model reveals clues to how blood starts clotting
Researchers at the University of Chicago have crafted a simple model for predicting when and where hemostasis - the technical term for blood clotting - will occur.   view more (2006-10-27)

Haemophilia Carriers Have A Reduced Risk Of Ischaemic Heart Disease (p 351)
Decreased blood clotting protects mothers of haemophiliacs against ischaemic heart disease claim researchers in this week's issue of THE LANCET. Clotting has a key role in ischaemic heart disease, and reduced clotting protects against the disease. Haemophilia, a genetic clotting disorder, mainly affects men and causes reduced blood clotting.... view more... (2003-07-30)

DVT Risk From Air Travel Unrelated To Reduced Air Pressure In Cabin (p 2207)
Results of a study published as a research letter in this week's issue of THE LANCET suggest that reduced air pressure (leading to decreased oxygen availability) in pressurised aircraft cabins is not associated with increased activity of the agents responsible for blood clotting and potential deep-vein thrombosis (DVT). The risk of venous... view more... (2003-06-25)

Monash researchers lead the way in blood clotting discovery
A Monash-led research team has discovered an entirely new mechanism that promotes blood clot formation - a major breakthrough that will impact on treatment and prevention of heart disease and stroke.   view more (2009-05-26)

New blood-thinning drug safer than rat poison
In an article reviewed by F1000 Medicine Faculty Members Robert Ruff, Brian Olshansky and Luis Ruilope, the blood-thinner dabigatran is shown to protect against stroke, blood clotting and major bleeding as effectively as warfarin, but with fewer side effects.   view more (2009-09-30)

New study suggests Rx estrogen delivery through the skin may show safety benefits as opposed to oral delivery
Transdermal delivery of estrogen therapy available by prescription "seems not to alter" the risk of venous thromboembolism (VTE), or blood clotting, in postmenopausal patients when compared to oral delivery, a new study suggests.   view more (2009-03-27)

Anti-clotting drug thins risk to pregnancy and surgery patients with blood disorder
Pregnancy and surgery patients with a serious blood disorder that causes excessive clotting have responded well to treatment with a man-made anti-clotting protein. Results from a study by researchers at Yale School of Medicine and other institutions were presented December 6 at the Annual Meeting of the American Society of Hematology (ASH) in San... view more... (2008-12-09)

UNC scientists discover 'gatekeeper' protein in blood clotting
New research from the University of North Carolina at Chapel Hill School of Medicine has identified a protein that may control blood clotting by keeping blood platelets from sticking together.   view more (2006-01-30)

Long airplane flight does not appear to increase risk of blood clots
Researchers simulating conditions of reduced cabin pressure and reduced oxygen levels, such as may be encountered during an 8-hour airplane flight, found no increase in the activation of the blood clotting system among healthy individuals.   view more (2006-05-17)

Aspirin treatment failure warning
Treatment failures occur with any drug and aspirin is no exception. Evidence is growing that some people will not respond to the anti-coagulant action of aspirin and the drug will not protect against cardiovascular events despite its regular intake.   view more (2005-08-10)

Aspirin and similar drugs may be associated with brain microbleeds in older adults
Individuals who take aspirin or other medications that prevent blood clotting by inhibiting the accumulation of platelets appear more likely to have tiny, asymptomatic areas of bleeding in the brain.   view more (2009-04-14)

A transplant in time
In hemophilia, a mutated gene prevents the production of a critical blood-clotting protein. Treatments for hemophilia and other such genetic diseases, when they exist, may consist of risky blood transfusions or expensive enzyme replacement therapy.   view more (2007-01-02)

Over-diagnosis Of Liver Failure After Paracetamol Poisoning?
Danish authors of a Research letter in this week's issue of THE LANCET suggest that there is the potential for clinicians to mistakingly diagnose liver failure after moderate paracetamol poisoning by relying solely on the measurement of one diagnostic marker. The use of acetylcysteine after paracetamol poisoning is of known therapeutic benefit;... view more... (2002-10-09)

Long-term anti-clotting therapy sweetens stenting outcomes in diabetic patients
A study showing that diabetic patients who are treated with long-term anti-clotting therapy are less likely to have a heart attack or die more than a year after stenting has been named among the best research papers presented at the 30th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interventions (SCAI), May 9-12,... view more... (2007-05-18)

Many oncologists unaware of cancer clot risk
Patients receiving cancer treatments are at greater risk of blood clots, yet more than a quarter of oncologists do not recognise their clotting effects and preventive measures are rarely used, finds a study in this week’s BMJ.   view more (2003-09-10)

Mayo researchers explore reasons for complications with kidney failure patients
Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.   view more (2005-08-18)

New Approach For Reducing Bleeding After Surgery
Encouraging findings from a study in this week's issue of THE LANCET suggest that factor VII-an agent involved in blood clotting-could be effective in reducing excessive blood loss during abdominal surgery.    Factor VII has been shown to promote blood clotting in patients with haemophilia. Marcel Levi from Academic Medical Centre,... view more... (2003-01-16)

UK researchers shed new light on a cause of recurrent miscarriages
Women who carry a particular genetic mutation that predisposes them to blood clots have a significantly higher chance of miscarrying, according to UK researchers in a report (Wednesday 30 January) in Europe's leading reproductive medicine journal Human Reproduction.* The first prospective study into the outcome of untreated pregnancies in a group... view more... (2002-01-26)

Blood-clotting protein modified for people with hard-to-treat hemophilia
Pathologists at The University of Texas Health Science Center at Houston have developed a chemically modified protein that may help people with a hard-to-treat form of a genetic bleeding disorder known as Hemophilia A.   view more (2008-05-20)

Alternatively spliced tissue factor identified as promising new biomarker for aggressive cancers
A recently discovered form of the protein that triggers blood clotting may play a key role in the molecular mechanisms leading to the growth of certain metastatic cancers, according to new research reported by an international team of scientists.   view more (2009-10-27)
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