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Xie Lab demonstrates the role of microRNA pathway
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary.   view more (2007-02-16)

Gaps in intestinal barrier could cause Crohn's disease
Scientists at the University of Liverpool believe gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease.   view more (2005-09-16)

Bones hold the key to blood renewal
Though we think of them as solid and permanent, our bones are actually constantly being rebuilt throughout our lives. A team of scientists at the Weizmann Institute of Science has now revealed how cells that work at remodeling the bones play a direct part in the ongoing renewal of another system... view more (2006-06-20)

Railway Maintenance Must Become Smarter
One of the conclusions of Arjen Zoeteman, who will defend his thesis on 22 November at TU Delft, is that significant amounts of money could be saved on the maintenance of European railway systems, including the Netherlands. Through a carefully structured schedule and a detailed analysis of... view more (2004-11-19)

Israel joins the Fifth Framework Programme
The agreement is effectively a renewal of the one signed in 1996 under the Fourth Framework Programme, which gave rise to 350 joint projects, many of which have already produced tangible results.   view more (1999-03-03)

Protein protects embryonic stem cells' versatility and self-renewal
A protein known as REST blocks the expression of a microRNA that prevents embryonic stem cells from reproducing themselves and causes them to differentiate into specific cell types, scientists at The University of Texas M. D. Anderson Cancer Center report in the journal Nature.   view more (2008-03-24)

Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow.   view more (2005-08-02)

Researchers discover important tool in understanding differentiation in human embryonic stem cells
Researchers at the University of Minnesota's Stem Cell Institute have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. The research appears in the November 2007 issue of Experimental Biology and Medicine.   view more (2007-10-25)

How do the rules of immunity change during chronic infections?
After a viral infection, a small percentage of the T cells generated to kill virus-infected cells remain on guard to establish long-term immunity.   view more (2007-04-10)

Ovarian cancer stem cells identified, characterized
Researchers at Yale School of Medicine have identified, characterized and cloned ovarian cancer stem cells and have shown that these stem cells may be the source of ovarian cancer's recurrence and its resistance to chemotherapy.   view more (2008-04-18)

Weizmann Institute suggests that immune cells help to maintain cognition and brain cell renewal
A team of scientists at the Weizmann Institute of Science, led by Prof. Michal Schwartz of the Neurobiology Department, has come up with new findings that may have implications in delaying and slowing down cognitive deterioration in old age.   view more (2006-01-16)

Scientists isolate leukemia stem cells in a model of human leukemia
Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston and their colleagues have isolated rare cancer stem cells that cause leukemia in a mouse model of the human disease.   view more (2006-07-18)

U-M team identifies gene that regulates blood-forming fetal stem cells
In the rancorous public debate over federal research funding, stem cells are generally assigned to one of two categories: embryonic or adult.   view more (2007-07-27)

USC stem cell study sheds new light on cell mechanism
Research from the University of Southern California (USC) has discovered a new mechanism to allow embryonic stem cells to divide indefinitely and remain undifferentiated.   view more (2008-05-22)

New type of drug shrinks primary breast cancer tumors significantly in just 6 weeks
A drug that targets the cell surface receptors that play an important role in many types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use.   view more (2008-04-17)

Wealth of genomic hotspots discovered in embryonic stem cells
In a paper published in Cell on June 13, 2008, Singapore scientists at the Genome Institute of Singapore (GIS) and the National University of Singapore (NUS) unveil an atlas that showing the location of "genomic hotspots" of essential protein "switches" (transcription factors)... view more (2008-06-16)

New stem-cell findings can help the body to cure itself
Researchers at Karolinska Institutet have identified an important mechanism that regulates how many new cells are produced by each intestinal stem cell. The study is published in the latest issue of the prestigious scientific journal, Cell.   view more (2006-06-16)

New method shows that neocortical nerve cells are not renewed
Most bodily organs continually die and regrow a little at a time. It takes two years, for example, for all the cells of the liver to be replaced by fresh ones. Research from Karolinska Institutet in Sweden now shows that there is one important exception to this - the nerve cells of the brain remain... view more (2006-08-14)

Hair-raising stem cells identified
Using an animal model, a research team led by Yann Barrandon at the EPFL (Ecole Polytechnique Federale de Lausanne) and the CHUV (Lausanne University Hospital) has discovered that certain cells inside the hair follicle are true multipotent stem cells, capable of developing into the many different... view more (2005-10-05)

The genetics of MLL leukemogenesis
In the November 1st issue of G&D, Dr. Michael Cleary (Stanford University School of Medicine) and colleagues identify the gene Meis1 as a critical player in the establishment of leukemia stem cells, and the development of MLL leukemia.   view more (2007-10-17)

Menstrual blood -- a valuable source of multipotential stem cells?
Researchers seeking new and more abundant sources of stem cells for use in regenerative medicine have identified a potentially unlimited, noncontroversial, easily collectable, and inexpensive source - menstrual blood.   view more (2008-04-23)

New study spotlights National Institutes of Health grant outcomes for clinical research
Although the need to translate basic science discoveries into the clinical arena is widely acknowledged, a new study by researchers at the Medical College of Wisconsin, in Milwaukee, and National Institutes of Health (NIH) identified reasons why clinical science grant applications receive less... view more (2008-07-28)

Cell division studies hint at future cancer therapy
When a cell's assets get divided between daughter cells, Dr. Quansheng Du wants to make sure both offspring do well.   view more (2008-01-23)

Mutation in blood stem cells provides clues to cancer development
The discovery suggests that development of a very specific inhibitor at the stem-cell level, to interfere with the pathway leading to the disease, could improve treatment for the cancer-causing disorder.   view more (2006-04-07)

Human embryonic stem cells remain embryonic because of epigenetic factors
A human embryonic stem cell is reined in - prevented from giving up its unique characteristics of self-renewal and pluripotency - by the presence of a protein modification that stifles any genes that would prematurely instruct the cell to develop into heart or other specialized tissue.   view more (2007-10-05)
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