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Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences.   view more (2006-11-28)

MIT: New tissue scaffold regrows cartilage and bone
MIT engineers and colleagues have built a new tissue scaffold that can stimulate bone and cartilage growth when transplanted into the knees and other joints.   view more (2009-05-12)

HRT prevents osteoarthritis of the knee
Long term use of hormone replacement therapy (HRT) seems to protect women from osteoarthritis of the knee, finds a study in the Annals of the Rheumatic Diseases. Osteoarthritis is the most common type of arthritis. It most often occurs in hip and knee joints, where loss of the tissue which prevents joint friction - cartilage - exposes the bone... view more... (2001-03-12)

Vigorous physical activity in children likely to stave off knee osteoarthritis in later life
Young children need to be highly physically active if they are to stave off degenerative joint disease, specifically osteoarthritis of the knee, suggest researchers in the British Journal of Sports Medicine.   view more (2003-09-25)

Brown researchers work toward ending cartilage loss
Scientists have long wrestled with how to aid those who suffer cartilage damage and loss. One popular way is to inject an artificial gel that can imitate cartilage's natural ability to act as the body's shock absorber. But that solution is temporary, requiring follow-up injections.   view more (2008-06-04)

A step forward in stem cell research
According to research published today, investigators from Memorial Sloan-Kettering Cancer Center (MSKCC) have used new techniques in the laboratory that allowed them for the first time to derive unlimited numbers of purified mesenchymal precursor cells from human embryonic stem cells (HESCs).   view more (2005-06-27)

Stem cell research to benefit horse owners and trainers
In a potential breakthrough for the performance horse industry (such as racing and polo), Melbourne scientists are aiming to harness stem cells to repair tendon, ligament, cartilage and bone damage in horses.   view more (2008-10-21)

Diabetes weakens your bones
Current research suggests that the inflammatory molecule TNF-α may contribute to delayed bone fracture healing in diabetics.   view more (2009-09-28)

Scientists move towards stem cell therapy trials to mend shattered bones
The UK Stem Cell Foundation, the Medical Research Council and Scottish Enterprise, in partnership with the Chief Scientist's Office, are funding a £1.4 million project to further the research at the University of Edinburgh with a view to setting up a clinical trial within two years.   view more (2008-02-19)

Scripps research scientists find cause of cartilage degeneration in osteoarthritis
The scientists describe their work in this week's Early Edition of the Proceedings of the National Academy of Sciences. In the study, the team shows how the loss of the protein HMGB2, found in the surface layer of joint cartilage, leads to the progressive deterioration of the cartilage that is the hallmark of osteoarthritis.   view more (2009-01-13)

Bioengineered tissue implants regenerate damaged knee cartilage
Knee cartilage injuries can be effectively repaired by tissue engineering and osteoarthritis does not stop the regeneration process concludes research led by scientists at the University of Bristol.   view more (2006-07-05)

Smoking worsens knee osteoarthritis
New findings from a study led by a Mayo Clinic rheumatologist indicate that men with knee osteoarthritis who smoke experience greater cartilage loss and more severe pain than men who do not smoke. Results will be published online this week in the Annals of the Rheumatic Diseases.   view more (2006-12-07)

Molecular 'marker' on stem cells aids research, perhaps therapies
A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT Southwestern Medical Center report.   view more (2006-12-04)

Mayo researchers note that stronger leg muscles can protect against knee osteoarthritis
Stronger quadriceps muscles in the legs can help protect against cartilage loss behind the kneecap, according to Mayo Clinic researchers presenting preliminary study data at the American College of Rheumatology Annual Meeting on Nov. 15.   view more (2006-11-15)

New Imaging Methods for Joints Provide Boost for Combating Osteoarthritis
Osteoarthritis is the most common joint disorder in the UK and affects more than one million people. In this disease the cartilage, the tough, slippery tissue that coats the end of the bones and provides smooth movement and shock absorbence, roughens and thins, and the surrounding bone grows thicker. Approximately 60% of people have osteoarthritis... view more... (1999-09-08)

Study identifies potential fix for damaged knees
Investigators from Hospital for Special Surgery have shown that a biodegradable scaffold or plug can be used to treat patients with damaged knee cartilage.   view more (2009-07-09)

Hope for arthritis stems from within
Leeds bioengineers have developed an innovative technique for cartilage repair combining the self-healing powers of the body with stem cell science to help young people avoid debilitating knee problems and give hope to arthritis sufferers.   view more (2006-01-31)

Factor stimulates cartilage growth from stem cells
A novel growth factor significantly improves the ability of specialized stem cells derived from human fat to be transformed into cartilage cells, according to Duke University Medical Center and Pratt School of Engineering researchers.   view more (2006-04-05)

Joint distraction promotes structural repair in patients with severe knee osteoarthritis
oint distraction (the use of a surgical frame around a degenerated joint to strengthen and promote repair) promotes cartilage repair in severe end stage osteoarthritis (OA) of the knee, as demonstrated for the first time by data presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France.   view more (2008-06-16)

Reexamination of T. rex verifies disputed biochemical remains
A new analysis of the remains of a Tyrannosaurus rex (T. rex) that roamed Earth 68 million years ago has confirmed traces of protein from blood and bone, tendons, or cartilage.   view more (2009-07-29)
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