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Bone Density Current Events | Bone Density News | 6

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Early signs that adult bone-marrow stem cells could regenerate brain tissue (p 1432)
Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of neurodegenerative disorders such as Parkinson's disease. Ethical... view more... (2004-04-28)

So-called "male menopause" in ageing men linked to higher risk of heart disease
The so-called "male menopause," with its lowered testosterone levels, may help to explain why men suffer more heart disease as they grow older, contend doctors in the current issue of Heart. Whether the male menopause, also referred to as the andropause, truly exists is a contentious matter, argue Dr Kevin Channer of the Royal... view more... (2003-01-14)

Dietary calcium could possibly prevent the spread of breast cancer to bone
A strong skeleton is less likely to be penetrated by metastasizing cancer cells, so a fortified glass of milk might be the way to block cancer's spread.   view more (2007-10-03)

Risk of falling is overlooked as the major cause of fractures in the elderly
An elderly person's risk of falling is too often overlooked when trying to prevent them from getting serious fractures, for instance of the hip or wrist, according to an article published in this week's BMJ.   view more (2008-01-18)

Gum Disease in Postmenopausal Women Linked to Oral Bone Loss
A study conducted in a large sample of postmenopausal women by University at Buffalo epidemiologists has provided new information on the prevalence of certain gum-disease-causing oral bacteria in this population and the association of the bacteria with oral bone loss.   view more (2007-06-18)

Invasive procedures still performed on conscious children despite new anaesthetic techniques
Many invasive bone marrow procedures are still carried out in conscious children despite the safety and effectiveness of modern anaesthetic and deep sedation techniques, finds a study in Archives of Disease in Childhood. The findings also show a striking difference between the North American and European approaches to managing painful procedures... view more... (2001-06-19)

Calcium important for nursing mothers' oral health
Mothers who breastfeed should be sure to have enough Calcium in their diet, or may risk bone loss around their teeth and gums, according to a new study that appears in the January issue of the Journal of Periodontology (JOP).   view more (2007-01-10)

Organon, University of Twente and Delft University of Technology are jointly searching for innovative therapies to promote bone regeneration
The Dutch pharmaceutical company Organon, the University of Twente (UT) and the Delft University of Technology have jointly started a project with the goal of finding breakthroughs in our understanding of the mechanisms of bone formation. This should lead to the development of new drugs and protocols for tissue engineering. This will strengthen... view more... (2004-03-22)

News from space for osteoporosis patients on earth: resistance is not futile
Results of a space experiment published online in The FASEB Journal have yielded a giant leap for science that could translate into an important step for mankind in the ongoing battle against osteoporosis.   view more (2009-03-30)

Hydrogels provide scaffolding for growth of bone cells
Hyaluronic hydrogels developed by Carnegie Mellon University researchers may provide a suitable scaffolding to enable bone regeneration. The hydrogels, created by Newell Washburn, Krzysztof Matyjaszewski and Jeffrey Hollinger, have proven to encourage the growth of preosteoblast cells, cells that aid the growth and development of bone. Doctoral... view more... (2008-08-18)

Bone-marrow Cell Transplantation Could Save Limbs (p 427)
Injecting a patient’s bone-marrow cells into their legs could help repair damaged circulatory systems in those with limb ischaemia, suggest authors of a trial in this week’s issue of THE LANCET. Lower limb ischaemia is due to narrowing of the arteries and is a common condition, which if left untreated can lead to gangrene, amputation,... view more... (2002-08-07)

Researchers discover protein that controls bone growth
A research team led by Dr. Pierre Moffatt of the Shriners Hospital for Children in Montreal and McGill University's Department of Human Genetics has uncovered the molecular mechanism by which the protein osteocrin controls bone growth - a discovery that may have important implications for people suffering from bone diseases affecting skeletal... view more... (2007-12-20)

Merck's odanacatib increased BMD over 2 years at key fracture sites in Phase IIB study
Two-year data from a Phase IIB study of odanacatib (formerly MK-0822), an investigational, selective cathepsin-K inhibitor in development for the treatment of osteoporosis by Merck & Co., Inc., demonstrated dose- dependent increases in bone mineral density (BMD) at the total hip, lumbar spine and femoral neck fracture sites and decreased... view more... (2008-09-17)

Women may be able to 'take break' from osteoporosis drug without losing benefit
Most postmenopausal women who took the osteoporosis drug alendronate for 5 years and then stopped did not have an increased risk for nonvertebral fractures in the next 5 years, suggesting the medication has a lasting effect, according to a study in the December 27 issue of JAMA.   view more (2006-12-27)

ETH Zurich and IBM improve diagnosis of osteoporosis
With the goal of developing an accurate, powerful and fast method to automate the analysis of bone strength, scientists of the ETH Zurich Departments of Mechanical and Process Engineering and Computer Science teamed up with supercomputing experts at IBM's Zurich Research Laboratory.   view more (2008-07-02)

July 23, 2009 Circulating osteogenic precursor (COP) cells form bone in vivo. Bone from Blood: Circulating Cells Form Bone Outside the Normal Skeleton, Penn Study Finds
The accepted dogma has been that bone-forming cells, derived from the body's connective tissue, are the only cells able to form the skeleton.   view more (2009-07-24)

Bone marrow cells can become functional gut lining cells
Researchers report the discovery that cells used in bone marrow transplantation can develop into new cells lining the gut, according to a study by Yale School of Medicine in the Proceedings of the National Academy of Sciences.   view more (2006-03-03)

Stem cell success points to way to regenerate parathyroid glands
An early laboratory success is taking University of Michigan researchers a step closer to parathyroid gland transplants that could one day prevent a currently untreatable form of bone loss associated with thyroid surgery.   view more (2009-09-30)

Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences.   view more (2006-11-28)

New bone marrow model could help people with sickle cell disease
A new model showing how sickle cell blood cells operate within bone marrow is presented at a conference in Austria today. Researchers at Imperial College London, who developed the model, hope that it will eventually be used by clinicians to advance more effective treatments for sickle cell disease.   This disease causes red blood cells to become... view more... (2005-02-18)
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