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Researchers reveal how long-term use of anti-inflammatory medication can cause osteoporosis
The steroid hormones glucocorticoids (GCs) are used at high doses to treat inflammatory and immune disorders, however they prompt bone loss and can cause osteoporosis, particularly when administered for prolonged periods.   view more (2006-07-28)

'Best of both worlds' — Targeting a single gene could inhibit bone decay and stimulate bone growth
Researchers at the University of Pennsylvania's School of Medicine have found by targeting the function of a single gene that it is possible to inhibit bone decay while simultaneously stimulating bone formation.   view more (2006-12-11)

Building stronger bones, 1 stem cell at a time
Mesenchymal stem cells (MSCs) are bone marrow-derived cells that are capable of giving rise to various cell types through a process known as differentiation.   view more (2008-01-25)

MDC researchers unravel key mechanism in pathogenesis of osteoporosis
Osteoporosis, or bone loss, is a disease that is most common in the elderly population, affecting women more often than men.    view more (2009-05-15)

Forsyth scientists find linkages between serotonin reuptake inhibitors and bone mass
Scientists at The Forsyth Institute have found that fluoxetine (Prozac), a drug used in the treatment of depression and obsessive-compulsive disorders, increases bone mass.   view more (2006-10-13)

Fabled 'vegetable lamb' plant contains potential treatment for osteoporosis
The "vegetable lamb" plant - once believed to bear fruit that ripened into a living baby sheep - produces substances that show promise in laboratory experiments as new treatments for osteoporosis, the bone-thinning disease.   view more (2009-10-15)

New research could help us deliver genes for new bone formation
UK scientists are working on new methods to regenerate cartilage and bone by delivering genes to stem cells within the body to instruct them to turn into bone cells.   view more (2005-09-29)

UAB Study Reveals Bone Coupling Factor Key to Skeletal Health
Researchers at the University of Alabama at Birmingham (UAB) have discovered a molecular coupling factor that helps bones grow and remodel themselves to stay strong, a finding that could lead to better bone-building therapies and new osteoporosis drugs, the researchers said   view more (2009-07-08)

Notch controls bone formation and strength
Notch, a protein known to govern the determination of cell differentiation into different kinds of tissues in embryos, plays a critical role in bone formation and strength later in life, said researchers from Baylor College of Medicine in Houston in a report that appears online today in the journal Nature Medicine.   view more (2008-02-25)

Reconstructing mandibular defects with bioengineered tooth and bone
Current strategies for jaw reconstruction require multiple procedures, first to repair the bone defect to offer sufficient support, and then to place the tooth implant.   view more (2008-04-07)

Bones from calves good for fastening tooth implants
On Friday, November 8, Mats Hallman, Department of Odontology, Jaw Surgery, Ume'å University in Sweden, will defend a thesis that presents favorable results from implanting bone powder from calves to anchor tooth implants in humans. Tooth implants have long been a well-tested method to create permanent teeth in toothless sections of the jaw.... view more... (2002-11-05)

Researchers present Phase 2 clinical results for Acologix AC-100
Today, researchers from Acologix (Hayward, CA, USA), the University of California (San Francisco, USA), and the University of Connecticut (Simsbury, USA) will announce the results of a Phase 2 clinical trial of AC-100 (also known as Dentonin), reporting that it met its primary goal of stimulating the formation of new dentin when applied directly... view more... (2006-06-30)

Trimming the fat boosts blood recovery after marrow transplant
Seeking ways to improve blood recovery after chemotherapy or bone marrow transplant, researchers at Children's Hospital Boston have discovered that fat cells, which accumulate in bone marrow as people age, inhibit the marrow's ability to produce new blood cells.   view more (2009-06-11)

Drawing a crowd: How progenitor cells are recruited to tumor blood vessels from the bone marrow
Cells within the bone marrow (progenitor cells) that express a protein called CD34 have been shown to leave the marrow and travel to sites of tissue injury to mediate repair.   view more (2006-02-24)

New evidence that green tea may help improve bone health
Researchers in Hong Kong are reporting new evidence that green tea - one of the most popular beverages consumed worldwide and now available as a dietary supplement - may help improve bone health.   view more (2009-09-17)

Dental researchers ID new target in fight against osteoporosis, periodontitis
Osteoporosis and periodontitis are common diseases whose sufferers must cope with weakness, injury and reduced function as they lose bone more quickly than it is formed.   view more (2009-05-19)

Research identifies protein in mice that regulates bone formation
Osteoporosis, a disease characterized by a decrease in bone mass and density and which makes people more susceptible to bone fractures and deformities, afflicts some 10 million Americans over the age of 50.   view more (2006-06-23)

Stem cell therapy grows new blood vessels
Research led by David Hess of the Robarts Research Institute at The University of Western Ontario has identified how to use selected stem cells from bone marrow to grow new blood vessels to treat diseases such as peripheral artery disease.   view more (2009-04-07)

Study identifies molecule essential for proper localization of blood stem cells
Scientists at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HCSI) have defined a molecule that dictates how blood stem cells travel to the bone marrow and establish blood and immune cell production.   view more (2006-01-16)

Lithium and bone healing
Researchers have described a novel molecular pathway that may have a critical role in bone healing and have suggested that lithium, which affects this pathway, has the potential to improve fracture healing.   view more (2007-07-31)
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