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Invasive procedures still performed on conscious children despite new anaesthetic techniques
Many invasive bone marrow procedures are still carried out in conscious children despite the safety and effectiveness of modern anaesthetic and deep sedation techniques, finds a study in Archives of Disease in Childhood. The findings also show a striking difference between the North American and... view more (2001-06-19)

Bone-marrow Cell Transplantation Could Save Limbs (p 427)
Injecting a patient’s bone-marrow cells into their legs could help repair damaged circulatory systems in those with limb ischaemia, suggest authors of a trial in this week’s issue of THE LANCET. Lower limb ischaemia is due to narrowing of the arteries and is a common condition, which if... view more (2002-08-07)

Early signs that adult bone-marrow stem cells could regenerate brain tissue (p 1432)
Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of... view more (2004-04-28)

Bone marrow cells can become functional gut lining cells
Researchers report the discovery that cells used in bone marrow transplantation can develop into new cells lining the gut, according to a study by Yale School of Medicine in the Proceedings of the National Academy of Sciences.   view more (2006-03-03)

New bone marrow model could help people with sickle cell disease
A new model showing how sickle cell blood cells operate within bone marrow is presented at a conference in Austria today. Researchers at Imperial College London, who developed the model, hope that it will eventually be used by clinicians to advance more effective treatments for sickle cell disease.... view more (2005-02-18)

Bone marrow hope for heart sufferers
New hope for sufferers of heart disease is possible, after research led by a University of Leicester surgeon indicates that bone marrow cells injected into a heart can help repair damage from a heart attack.   view more (2002-11-27)

Drawing a crowd: How progenitor cells are recruited to tumor blood vessels from the bone marrow
Cells within the bone marrow (progenitor cells) that express a protein called CD34 have been shown to leave the marrow and travel to sites of tissue injury to mediate repair.   view more (2006-02-24)

NC State Is First University in Nation to Offer Canine Bone Marrow Transplants
Dogs suffering from lymphoma will be able to receive the same type of medical treatment as their human counterparts, as North Carolina State University becomes the first university in the nation to offer canine bone marrow transplants in a clinical setting.   view more (2008-09-04)

Developing cancer treatments directed at critical developmental pathway
Researchers from the University of Pennsylvania School of Medicine and colleagues discovered that the Notch signaling pathway, which determines the development of many cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells.   view more (2008-04-11)

Bone Marrow Stem Cells May Cure Eye Disease
Adult bone marrow stem cells may help cure certain genetic eye diseases, according to UC researchers.   view more (2007-05-11)

Stem cells speed growth of healthy liver tissue
For the first time, researchers have used adult bone marrow stem cells to regenerate healthy human liver tissue, according to a study published in the April issue of the journal Radiology.   view more (2007-03-27)

Protein key to control, growth of blood cells
New research sheds light on the biological events by which stem cells in the bone marrow develop into the broad variety of cells that circulate in the blood. The findings may help improve the success of bone marrow transplants and may lead to better treatments for life-threatening blood diseases.   view more (2008-08-14)

ESC Congress 2004: Converting cells into heart muscle
Bone marrow derived stem cells can give rise to heart muscle cells. This plasticity concept - the ability of bone marrow cell to transdifferentiate into heart muscle cell - is supported by experimental and clinical data. Another possibility is to replace the missing function by causing... view more (2004-08-30)

Study identifies molecule essential for proper localization of blood stem cells
Scientists at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HCSI) have defined a molecule that dictates how blood stem cells travel to the bone marrow and establish blood and immune cell production.   view more (2006-01-16)

Bone drug could help prevent the spread of breast cancer
Maintaining bone density could be a key to decreasing the spread of cancer in women with locally advanced breast cancer, according to research at Washington University School of Medicine in St. Louis.   view more (2008-05-19)

First gene associated with myeloproliferative diseases
Myelodysplastic / myeloproliferative diseases (MDS/MPD) are blood stem cell disorders characterized by ineffective formation and development of blood cells in the bone marrow, resulting in abnormal development of bone marrow precursor cells and a reduction in the number of blood cells.   view more (2005-08-26)

Treating male infertility with stem cells
New research has examined the usefulness of bone marrow stem cells for treating male infertility, with promising results. The related report by Lue et al, "Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure," appears in the... view more (2007-03-02)

USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought.   view more (2006-10-09)

New finding may aid adult stem cell collection
Cincinnati scientists have discovered how blood-regenerating stem cells move from bone marrow into the blood stream.   view more (2005-07-28)

Malfunctioning bone marrow cells sabotage nerve cells in diabetes
Malfunctioning bone marrow cells that produce insulin appear to cause a dangerous nerve condition called neuropathy that disables many people with diabetes, said a research team led by Baylor College of Medicine in Houston.   view more (2005-08-23)

ESC Congress 2003: Bone marrow cells to repair myocardial infarction. Are they really capable of replacing injured cells and reducing infarct size?
IMPORTANT: This press release accompanies a poster or oral session given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology ESC Congress 2003: The heart is incapable of cardiocell... view more (2003-08-31)

Discovery points to more effective ways of regulating cell signalling
A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.   view more (2006-04-21)

Gene therapy protects mice from the effects of whole-body irradiation
University of Pittsburgh School of Medicine researchers have successfully protected mice against the damaging effects that radiation can have on bone marrow using gene therapy.   view more (2006-06-05)

Protein level predicts who will develop deadly complication after marrow transplant
Researchers could determine one week after a bone marrow transplant which patients were likely to develop a serious and deadly complication, making them candidates for preventive treatment before any symptoms occur.   view more (2006-02-17)

Scientists Discover Cause Of Leukaemia That Halted Treatment Trial For 'Baby-in-a-Bubble' Syndrome
Medical Research Council (MRC) scientists have helped establish the cause of the leukaemia which developed in two young patients taking part in a pioneering gene therapy trial to treat the fatal 'baby-in-a-bubble' syndrome, severe combined immunodeficiency (X-SCID). The trial at the Necker-Enfants... view more (2003-10-16)

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