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Invasive procedures still performed on conscious children despite new anaesthetic techniques
Many invasive bone marrow procedures are still carried out in conscious children despite the safety and effectiveness of modern anaesthetic and deep sedation techniques, finds a study in Archives of Disease in Childhood. The findings also show a striking difference between the North American and European approaches to managing painful procedures... view more... (2001-06-19)

Bone-marrow Cell Transplantation Could Save Limbs (p 427)
Injecting a patient’s bone-marrow cells into their legs could help repair damaged circulatory systems in those with limb ischaemia, suggest authors of a trial in this week’s issue of THE LANCET. Lower limb ischaemia is due to narrowing of the arteries and is a common condition, which if left untreated can lead to gangrene, amputation,... view more... (2002-08-07)

Early signs that adult bone-marrow stem cells could regenerate brain tissue (p 1432)
Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of neurodegenerative disorders such as Parkinson's disease. Ethical... view more... (2004-04-28)

Children's Hospital study demonstrates how bone marrow transplant can cure sickle cell disease
A unique approach to bone marrow transplantation pioneered in part by a Children's Hospital of Pittsburgh of UPMC physician has proven to be the only safe and effective cure for sickle cell disease, according to a new study.   view more (2008-11-07)

Bone marrow cells can become functional gut lining cells
Researchers report the discovery that cells used in bone marrow transplantation can develop into new cells lining the gut, according to a study by Yale School of Medicine in the Proceedings of the National Academy of Sciences.   view more (2006-03-03)

A new method for bone-marrow-derived liver stem cells isolation and proliferation
Great interest has been aroused in the identification and isolation of liver stem cells from bone marrow cells. Several subsets of bone marrow cells have been found to have the potential to differentiate into hepatocytes, however, sorting based on immunological methods is difficult because of the complicated surface markers of the stem cells;... view more... (2009-04-15)

Bone marrow cell therapy may be beneficial for patients with ischemic heart disease
The injection of bone marrow cells into the heart of patients with chronic myocardial ischemia (reduced blood flow to some areas of the heart) was associated with modest improvements in blood flow and function of the left ventricle.   view more (2009-05-20)

New bone marrow model could help people with sickle cell disease
A new model showing how sickle cell blood cells operate within bone marrow is presented at a conference in Austria today. Researchers at Imperial College London, who developed the model, hope that it will eventually be used by clinicians to advance more effective treatments for sickle cell disease.   This disease causes red blood cells to become... view more... (2005-02-18)

Bone marrow hope for heart sufferers
New hope for sufferers of heart disease is possible, after research led by a University of Leicester surgeon indicates that bone marrow cells injected into a heart can help repair damage from a heart attack.   view more (2002-11-27)

Drawing a crowd: How progenitor cells are recruited to tumor blood vessels from the bone marrow
Cells within the bone marrow (progenitor cells) that express a protein called CD34 have been shown to leave the marrow and travel to sites of tissue injury to mediate repair.   view more (2006-02-24)

NC State Is First University in Nation to Offer Canine Bone Marrow Transplants
Dogs suffering from lymphoma will be able to receive the same type of medical treatment as their human counterparts, as North Carolina State University becomes the first university in the nation to offer canine bone marrow transplants in a clinical setting.   view more (2008-09-04)

Developing cancer treatments directed at critical developmental pathway
Researchers from the University of Pennsylvania School of Medicine and colleagues discovered that the Notch signaling pathway, which determines the development of many cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells.   view more (2008-04-11)

Bone Marrow Stem Cells May Cure Eye Disease
Adult bone marrow stem cells may help cure certain genetic eye diseases, according to UC researchers.   view more (2007-05-11)

Bone marrow cells can heal nerves in diabetes model
Transplanting cells that replenish blood vessels can also restore nerve function in an animal model of diabetic neuropathy, Emory researchers have found.   view more (2009-02-05)

Trimming the fat boosts blood recovery after marrow transplant
Seeking ways to improve blood recovery after chemotherapy or bone marrow transplant, researchers at Children's Hospital Boston have discovered that fat cells, which accumulate in bone marrow as people age, inhibit the marrow's ability to produce new blood cells.   view more (2009-06-11)

Potential risk identified in transfusions of platelets before bone marrow transplant
Research on blood transfusions points to a potential risk of transfusing donated platelets, especially to patients with bone marrow failure syndromes who are subsequently candidates for bone marrow transplantation.   view more (2009-08-11)

Stem cells speed growth of healthy liver tissue
For the first time, researchers have used adult bone marrow stem cells to regenerate healthy human liver tissue, according to a study published in the April issue of the journal Radiology.   view more (2007-03-27)

Biomedical researchers create artificial human bone marrow in a test tube
Artificial bone marrow that can continuously make red and white blood cells has been created in a University of Michigan lab.    view more (2008-12-23)

Protein key to control, growth of blood cells
New research sheds light on the biological events by which stem cells in the bone marrow develop into the broad variety of cells that circulate in the blood. The findings may help improve the success of bone marrow transplants and may lead to better treatments for life-threatening blood diseases.   view more (2008-08-14)

ESC Congress 2004: Converting cells into heart muscle
Bone marrow derived stem cells can give rise to heart muscle cells. This plasticity concept - the ability of bone marrow cell to transdifferentiate into heart muscle cell - is supported by experimental and clinical data. Another possibility is to replace the missing function by causing transdifferentiation of existing cells. Transdifferentiation... view more... (2004-08-30)
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