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Bone Marrow Current Events | Bone Marrow News | 6

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Finding key to cancer drug Gleevec's limitations
University of Michigan researchers have developed an animal model that provides strong evidence why imatinib, marketed as Gleevec, helps patients with chronic myeloid leukemia survive longer, but does not keep the disease from returning if treatment ends.   view more (2009-08-05)

Surgery to improve academic ability in children with congenital heart disease may not work
Surgery to correct congenital heart disease in children may not result in the hoped for improvements in intellectual and academic ability, suggests research in Heart. It is generally believed that congenital heart disease may impair intellectual and academic performance either because of the diminished oxygen supply to the brain and/or missed... view more... (2001-05-17)

Lost in the labyrinth
Blood cells have limited lifespans, which means that they must be continually replaced by calling up reserves, and turning these into the blood cell types needed by the body.   view more (2006-09-05)

Bone marrow may restore cells lost in vision diseases
University of Florida scientists conducting experiments with mice have found evidence that the body naturally replenishes small amounts of cells in the eye essential for healthy vision.   view more (2006-06-09)

Stem Cell Study for Patients with Heart Attack Damage Seeks to Regenerate Heart Muscle
Rush cardiologists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue.   view more (2006-04-21)

Repair not destruction: A new approach to treating retinopathy
Many diseases of the eye (such as retinopathy of prematurity (ROP) and diabetic retinopathy) that result in loss of vision are the result of the growth of abnormal blood vessels that leak and bleed.   view more (2006-11-17)

Reconstructive surgeon aims for rejection-free limb transplantation
Years ago, the idea of attaching a donor limb onto a patient's body would have been the stuff of science fiction.   view more (2006-09-08)

Immune therapy can protect against or treat later lymphoma
Specially developed immune system cells that target the common Epstein-Barr virus can protect immune-suppressed bone marrow transplant recipients against lymph system disease and cancers that arise from the viral infection.   view more (2009-11-03)

Dampened hopes for transplanting bone marrow stem cells in heart attacks
There is little, if any, evidence that adult stem cells can build other cells in an adult organism than those formed in the organs they themselves come from. At any rate, blood stem cells do not convert to heart muscle cells in a damaged heart, which was previously hoped. This has been shown by a research team from the Stem Cell Center at Lund... view more... (2004-05-06)

Blood stem cells fight invaders, study finds
No other stem cell is more thoroughly understood than the blood, or hematopoietic, stem cell.   view more (2007-11-30)

Bone Implant Offers Hope for Skull Deformities
A synthetic bone matrix offers hope for babies born with craniosynostosis, a condition that causes the plates in the skull to fuse too soon.   view more (2009-11-20)

Bone marrow-derived stem cells may offer novel therapeutic option for skin disorder
Stem cells derived from bone marrow may serve as a novel therapeutic option to treat a disease called epidermolysis bullosa (EB), a disorder characterized by extraordinarily fragile skin, according to a study prepublished online in Blood, the official journal of the American Society of Hematology.    view more (2008-12-05)

Liposuctioned fat stem cells to repair bodies
Expanding waistlines, unsightly bulges: people will gladly remove excess body fat to improve their looks. But unwanted fat also contains stem cells with the potential to repair defects and heal injuries in the body.   view more (2007-02-23)

Engineered Blood Vessels Function like Native Tissue
Blood vessels that have been tissue-engineered from bone marrow adult stem cells may in the future serve as a patient's own source of new blood vessels following a coronary bypass or other procedures that require vessel replacement.   view more (2007-07-09)

Potential diagnostic marker indicates effectiveness of anti-angiogenic drugs
If an anti-angiogenic drug is successfully starving a cancer patient's tumor to death, the number of endothelial cells circulating in the individual's bloodstream will decrease, thus providing a potential biomarker for gauging the medication's effectiveness.   view more (2006-09-18)

MIT bioengineer advances survival, promise of adult stem cells
MIT researchers have developed a technique to encourage the survival and growth of adult stem cells, a step that could help realize the therapeutic potential of such cells.   view more (2007-02-28)

Adult stem cell application effective in treatment of peripheric vascular disease
Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.   view more (2008-01-25)

Adult stem cells may be beneficial for certain cardiovascular disorders and autoimmune diseases
A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders.   view more (2008-02-27)

Researchers reveal how long-term use of anti-inflammatory medication can cause osteoporosis
The steroid hormones glucocorticoids (GCs) are used at high doses to treat inflammatory and immune disorders, however they prompt bone loss and can cause osteoporosis, particularly when administered for prolonged periods.   view more (2006-07-28)

Cancer cells in blood can identify risk of recurrence in breast cancer
Cancer cells circulating in the blood, or circulating tumour cells (CTCs), are known to be associated with a bad prognosis in women with metastatic breast cancer.   view more (2007-09-25)
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