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Bone Marrow Transplants Current Events | Bone Marrow Transplants News | 3

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First gene associated with myeloproliferative diseases
Myelodysplastic / myeloproliferative diseases (MDS/MPD) are blood stem cell disorders characterized by ineffective formation and development of blood cells in the bone marrow, resulting in abnormal development of bone marrow precursor cells and a reduction in the number of blood cells.   view more (2005-08-26)

Largest study of unrelated bone marrow transplantation for leukemia serves as benchmark
Together with 16 other institutions in the United States, University of Minnesota researchers led the largest study to date in patients with leukemia and related disorders undergoing bone marrow transplantation from unrelated donors.   view more (2005-08-03)

New research lights up chronic bacterial infection inside bone
A new report demonstrates how a sensitive imaging technique gives scientists the upper hand in seeking out bacteria in chronic infections.   view more (2008-12-23)

Treating male infertility with stem cells
New research has examined the usefulness of bone marrow stem cells for treating male infertility, with promising results. The related report by Lue et al, "Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure," appears in the March issue of The American Journal of Pathology.   view more (2007-03-02)

USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought.   view more (2006-10-09)

Finding key to cancer drug Gleevec's limitations
University of Michigan researchers have developed an animal model that provides strong evidence why imatinib, marketed as Gleevec, helps patients with chronic myeloid leukemia survive longer, but does not keep the disease from returning if treatment ends.   view more (2009-08-05)

Immune exhaustion driven by antigen in chronic viral infection
A main reason why viruses such as HIV or hepatitis C persist despite a vigorous initial immune response is exhaustion. The T cells, or white blood cells, fighting a chronic infection eventually wear out.   view more (2009-05-14)

Malfunctioning bone marrow cells sabotage nerve cells in diabetes
Malfunctioning bone marrow cells that produce insulin appear to cause a dangerous nerve condition called neuropathy that disables many people with diabetes, said a research team led by Baylor College of Medicine in Houston.   view more (2005-08-23)

ESC Congress 2003: Bone marrow cells to repair myocardial infarction. Are they really capable of replacing injured cells and reducing infarct size?
IMPORTANT: This press release accompanies a poster or oral session given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology ESC Congress 2003: The heart is incapable of cardiocell regeneration after myocardial infarction or other... view more... (2003-08-31)

Discovery points to more effective ways of regulating cell signalling
A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.   view more (2006-04-21)

Stem cell therapy grows new blood vessels
Research led by David Hess of the Robarts Research Institute at The University of Western Ontario has identified how to use selected stem cells from bone marrow to grow new blood vessels to treat diseases such as peripheral artery disease.   view more (2009-04-07)

Gene therapy protects mice from the effects of whole-body irradiation
University of Pittsburgh School of Medicine researchers have successfully protected mice against the damaging effects that radiation can have on bone marrow using gene therapy.   view more (2006-06-05)

Reconstructive surgeon aims for rejection-free limb transplantation
Years ago, the idea of attaching a donor limb onto a patient's body would have been the stuff of science fiction.   view more (2006-09-08)

Role of the nervous system in regulating stem cells discovered
New study by Mount Sinai researchers may lead to improved stem cell therapies for patients with compromised immune systems due to intensive cancer therapy or autoimmune disease.   view more (2006-01-27)

Just in time for spring: Scientists find the cellular on and off switch for allergies and asthma
If you're one of the millions who dread the spring allergy season, things are looking up.   view more (2009-04-30)

Stem-cell transfer could improve cardiac functioning after heart attack (pp 121, 141)
Results of a randomised trial in this week's issue of THE LANCET suggest that the transfer of adult stem cells derived from bone marrow could improve cardiac functioning after heart attack. Evidence is emerging that adult stem cells from bone marrow have therapeutic potential for restoring cardiac cells among people who have had heart attack.... view more... (2004-07-07)

Are bone marrow mononuclear cells effective in reducing hepatic lesions?
Liver fibrosis occurs in the setting of chronic injury caused by different etiologies constituting a serious worldwide public health problem. In addition to schistosomiasis, hepatopathies due to alcohol, viral hepatitis, drugs, metabolic and autoimmune diseases, and congenital abnormalities are important causes of liver fibrosis.   view more (2008-10-24)

Early heart attack therapy with bone marrow extract improves cardiac function
A UCSF study for the treatment of heart failure after heart attack found that the extract derived from bone marrow cells is as effective as therapy using bone marrow stem cells for improving cardiac function, decreasing the formation of scar tissue and improving cardiac pumping capacity after heart attack.   view more (2009-06-30)

Molecular 'marker' on stem cells aids research, perhaps therapies
A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT Southwestern Medical Center report.   view more (2006-12-04)

OHSU Cancer Institute research discovery opens new window to understanding chronic myeloid leukemia
Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML).   view more (2007-12-10)
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