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Bone Marrow Transplants Current Events | Bone Marrow Transplants News | 5

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Unique role for blood formation gene identified
All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found.   view more (2007-09-13)

Reexamination of T. rex verifies disputed biochemical remains
A new analysis of the remains of a Tyrannosaurus rex (T. rex) that roamed Earth 68 million years ago has confirmed traces of protein from blood and bone, tendons, or cartilage.   view more (2009-07-29)

Stem cells may look malignant, not act it
Bone marrow stem cells attracted to the site of a cancerous growth frequently take on the outward appearance of the malignant cells around them, University of Florida researchers report in a paper to be published in the August issue of Stem Cells.   view more (2007-05-24)

Researchers aim to cut future need for liver transplants
University of Edinburgh scientists have identified primitive liver cells —possibly dormant from the earliest developmental stage of a human being — which have the potential to mature into different cells types and help repair a failing liver.   view more (2006-07-07)

Mouse model reveals that oncoprotein induces abnormal preleukemic blood cell progenitors
Scientists have developed a novel mouse model for leukemia that reveals critical information about the mechanisms involved in leukemia progression and provides a model system for evaluation of new drugs for treatment of leukemia.   view more (2006-01-18)

Leukemic cells find safe haven in bone marrow
The cancer drug asparaginase fails to help cure some children with acute lymphoblastic leukemia (ALL) because molecules released by certain cells in the bone marrow counteract the effect of that drug, according to investigators at St. Jude Children's Research Hospital.   view more (2007-03-23)

Intraspinal implant of mesenchymal stem cells may not heal the demyelinated spinal cord
Multiple sclerosis is a disease caused by the loss of the myelinated sheath surrounding the nerve fibers of the spinal cord.   view more (2008-11-13)

Strategy for mismatched stem cell transplants triggers protection against graft-vs.-host disease
A new technique being tested in stem-cell transplants from imperfectly matched donors has revealed a striking, unforeseen response that can suppress graft-versus-host disease, a common and dangerous complication of mismatched transplants, report scientists from Dana-Farber Cancer Institute.   view more (2009-10-08)

Bones hold the key to blood renewal
Though we think of them as solid and permanent, our bones are actually constantly being rebuilt throughout our lives. A team of scientists at the Weizmann Institute of Science has now revealed how cells that work at remodeling the bones play a direct part in the ongoing renewal of another system — the blood.   view more (2006-06-20)

Blood stem cell growth factor reverses memory decline in mice
A human growth factor that stimulates blood stem cells to proliferate in the bone marrow reverses memory impairment in mice genetically altered to develop Alzheimer's disease, researchers at the University of South Florida and James A. Haley Hospital found.   view more (2009-07-02)

Reconstructing mandibular defects with bioengineered tooth and bone
Current strategies for jaw reconstruction require multiple procedures, first to repair the bone defect to offer sufficient support, and then to place the tooth implant.   view more (2008-04-07)

New method to analyse the Major Histocompatibility Complex (MHC) of the human genome
Scientists at Fred Hutchinson Cancer Research Center have developed a new method for analyzing the Major Histocompatibility Complex (MHC) of the human genome.   view more (2006-04-24)

Central nervous system infections rare but devastating following heart transplantation
Central nervous system infections develop infrequently following heart transplants but are a significant predictor of death, according to an article posted online today that will appear in the December 2007 print issue of Archives of Neurology.   view more (2007-10-09)

Healing the heart with bone marrow cells
Researchers at the McEwen Centre for Regenerative Medicine at Toronto General Hospital have discovered the 'SOS' distress signal that mobilizes specific heart repair cells from the bone marrow to the injured heart after a heart attack.   view more (2006-07-05)

Strategies Allow For Drug-free Organ Transplants In Some, Just One Pill A Week For Others, Report Researchers At International Congress Of The Transplantation Society
Results of three studies presented today at the International Congress of The Transplantation Society provide encouraging evidence that a patient’s immune system can be fooled into accepting a transplanted organ without the need for anti-rejection drugs. According to one study conducted in India, patients are off the immunosuppressive drug... view more... (2002-08-20)

Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
New research from scientists at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center underscores the importance of preventing recurring acid reflux while also uncovering tantalizing clues on how typical acid reflux can turn potentially cancerous.   view more (2007-08-10)

Dormant stem cells for emergencies
Many specialized cells, such as in the skin, intestinal mucosa or blood, have a lifespan of only a few days. For these tissues to function, a steady replenishment of specialized cells is indispensable. This is the task of so-called "adult" stem cells also known as tissue stem cells.   view more (2008-12-05)

Clinical trial demonstrates safety of pre-transplant expansion of umbilical cord blood stem cells
Taking blood stem cells collected from an umbilical cord into the lab and expanding their number before transplanting them to replace a patient's blood supply is as safe as a standard cord blood transplant, researchers reported today at the 50th Annual Meeting of the American Society of Hematology.   view more (2008-12-09)

PET Can Help Guide Treatment Decisions for a Common Pediatric Cancer
A new study published in the August issue of The Journal of Nuclear Medicine shows that positron emission tomography (PET) is an important tool for depicting the extent of neuroblastoma in some patients, particularly for those in the early stages of the disease.   view more (2009-08-03)

Genome discovery will help combat disease and lead to new drugs
An international consortium of researchers led by the University of Manchester has cracked the gene code behind a key family of fungi, which includes both the leading cause of death in leukaemia and bone marrow transplant patients and an essential ingredient of soy sauce.   view more (2005-12-22)
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