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Molecular structure reveals how botulinum toxin attaches to nerve cells
Botulism is a life-threatening disease caused by exposure to botulinum neurotoxins, which are among the most potent toxins known. These neurotoxins are produced by Clostridium botulinum, a bacterium found in soil and food. view more (2006-12-14)
Very long term effects of Botox still unknown
The use of botulinum toxin for facial cosmetic enhancement has established its new image as a glamour drug, but its unlicensed use is increasing dramatically for certain conditions, ahead of clear scientific evidence. Although negative side effects are few, its very long term effects are still unknown, warns a neurology expert in this week’s... view more... (2002-11-20)
Pioneering research into health benefits of beauty treatment
Pioneering medical research is going on at the University of Leicester into the use of Botulinum toxin - commonly thought of as a beauty treatment - for bladder problems. view more (2007-03-07)
Researchers develop new ultrasensitive assay to detect most poisonous substance known
Scientists at City of Hope and the California Department of Public Health have developed a new ultrasensitive assay to detect botulinum neurotoxin. view more (2008-05-01)
NEW LOOK ENVIRONMENT AWARD FOR ENGINEERS LAUNCHED FOR 1999
The competition, the only award to recognise the achievements of individual engineers in their work to protect and enhance the environment, is reshaped for 1999 with a totally new class structure that mirrors current environmental concerns and Government initiatives. view more (1999-03-11)
Genome of Clostridium botulinum reveals the background to world's deadliest toxin
The genome of the organism that produces the world's most lethal toxin is revealed today. This toxin is the one real weapon in the genome of Clostridium botulinum and less than 2 kg - the weight of two bags of sugar - is enough to kill every person on the planet. view more (2007-05-29)
Botulism bug has few genome wrinkles
The genome of the organism that produces the world's most lethal toxin is revealed today. This toxin is the one real weapon in the genome of Clostridium botulinum and less than 2 kg - the weight of two bags of sugar - is enough to kill every person on the planet. view more (2007-05-24)
Study helps explain why botulinum toxin is so deadly
A pilot without a map can locate an airport by first finding a nearby landmark, like a big river, and then searching for the airport. view more (2006-12-14)
Botox Injections May Improve Facial-Wound Healing, Minimize Scars
Botulinum toxin, the same Botox used to treat facial wrinkles, helps facial wounds heal with less scarring, according to results of a study published in the August issue of Mayo Clinic Proceedings. view more (2006-08-21)
Study reveals molecular basis of botulism toxin's deadly activity
In the study, the scientists reveal the mysterious structural basis of the remarkably strong interaction that botulinum toxins form with nerve cells, a union so robust that a single toxin molecule can completely incapacitate a nerve cell. view more (2006-12-18)
Highly concentrated botulinum preparation for cosmetic injections can result in severe illness
An examination of 4 cases of botulism following cosmetic injections to the face indicates that the adults received a highly concentrated, unlicensed preparation that resulted in toxin levels up to 40 times the estimated human lethal dose. view more (2006-11-22)
Botox for newborns
Botulinum toxin, also called Botox, is best known as one of the most commonly used molecules to reduce wrinkles. It is also known as one of the most poisonous naturally occurring substances. view more (2008-03-18)
Scientists reveal how deadly toxin hijacks cells
Scientists have pinpointed exactly how botulinum neurotoxin A-a potential agent of biological warfare and one of the most lethal toxins known to man-is able to sneak into cells. view more (2006-03-17)
Botulism study could lead to new vaccines and treatments to counter bioterrorist attacks
Of all the weapons in the bioterrorist arsenal, none is as potent as botulinum neurotoxin, which causes botulism-a potentially fatal disease with symptoms that include severe paralysis of the limbs and respiratory muscles. view more (2006-12-14)
Scientists Determine Drug Target for the Most Potent Botulinum Neurotoxin
Botulinum neurotoxin -- responsible for the deadly food poisoning disease botulism and for the beneficial effects of smoothing out facial wrinkles - can also be used as a dreaded biological weapon. view more (2008-04-30)
Scientists Reveal Structure of New Botulism Nerve Toxin Subtype
cientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a third subtype of botulinum neurotoxin - a deadly toxin produced by certain bacteria that causes the disease botulism, and is also used in cosmetic and therapeutic applications such as reducing wrinkles and calming a... view more... (2008-12-23)
Botulinum toxin helps facial scars heal better, Mayo Clinic finds
Mayo Clinic researchers have found that treating a facial wound in the early healing phase with botulinum toxin (BOTOX®) improves the appearance of a scar later. The findings are published in the August issue of Mayo Clinic Proceedings. view more (2006-08-10)
Wound botulism
In a case study in PLoS Medicine, doctors report on the case of a 35 year old heroin user who came to the accident and emergency department with double vision, slurred speech, drooping eyelids, and eye muscle weakness. The diagnosis turned out to be wound botulism. view more (2006-12-26)
Study shows Botox decreases pain and intensity of spasticity following a stroke
Final results from a multi-center study shows that repeated treatments of botulinum toxin type A (BoNTA or Botox®) over one year is well tolerated and results in a significant decrease in spasticity, pain frequency and average pain intensity in upper limbs following stroke. view more (2007-05-03)
'Botox' can ease writer's cramp
"Botox"' the popular anti- wrinkle treatment, can also ease writer's cramp, suggests a small study published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry. view more (2006-12-21)
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