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Botulinum Toxin Current Events | Botulinum Toxin News | 3

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The first gene-encoded amphibian toxin isolated
Researchers in China have discovered the first protein-based toxin in an amphibian -a 60 amino acid neurotoxin found in the skin of a Chinese tree frog. This finding may help shed more light into both the evolution of amphibians and the evolution of poison.   view more (2009-08-18)

Bacteria pack their own demise
Numerous pathogens contain an 'internal time bomb', a deadly mechanism that can be used against them. After years of work, VIB researchers at the Vrije Universiteit Brussel (VUB) were able to determine the structure and operating mechanism of the proteins involved.   view more (2009-07-31)

Plant pathogen yields substance to fight neuroblastoma
Drug treatment of neuroblastoma, a tumor of the nervous system in children, poses major problems. Therefore, scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have been searching for substances that are suitable as a basis for developing better drugs. Now they have found a candidate: HC-toxin, which is... view more... (2008-01-18)

Ricin's Deadly Action Revealed by Glowing Probes
A new chemical probe can rapidly detect ricin, a deadly poison with no known antidote that is feared to be a potential weapon for terrorists and cannot quickly be identified with currently available tests.   view more (2008-08-07)

Transgenic maize is more susceptible to aphids
The environmental consequences of transgenic crops are the focus of numerous investigations, such as the one published in the journal PloS ONE.   view more (2007-08-30)

Genes key to staph disease severity, drug resistance found hitchhiking together
Scientists studying Staphylococcus bacteria, including methicillin-resistant S. aureus (MRSA), have discovered a potent staph toxin responsible for disease severity.   view more (2009-08-03)

Anthrax inhibitor counteracts toxin, may lead to new therapeutics
Researchers from Rensselaer Polytechnic Institute and the University of Toronto have designed a nanoscale assembly of molecules that successfully counteracts and inhibits anthrax toxin in animal and laboratory experiments.   view more (2006-04-24)

Urologist uses Botox to treat debilitating condition
Eight years ago, Lynette Kunz suffered a severe spinal cord injury that left her a quadriplegic and sufferer of involuntary bladder contractions. The condition constantly interfered with her daily life.   view more (2007-12-06)

What makes C-Diff superbug deadly?
A major breakthrough about the potentially deadly superbug Clostridium difficile (C-diff) could lead to new ways to combat the bacterium, according to a study to be published March 1 in the journal Nature.   view more (2009-03-02)

Shield against assassin`s poison
Just a trace of ricin on the sharpened tip of an umbrella was enough to kill the Bulgarian dissident Georgi Markov, after an infamous attack on London`s Waterloo Bridge in 1978. Now a vaccine against this lethal toxin could soon be available - and it may be needed. "A big stash of ricin was found in the caves of Afghanistan," says Ellen Vitetta of... view more... (2002-09-11)

Brown Chemist Finds Gene That Enables Gray Mold to Kill Plant Cells
Gray mold is a gardener's nightmare. The fungus, also known by its scientific name Botrytis cinerea, is a scourge to more than 200 agricultural and ornamental plant species, including staples such as tomatoes, strawberries, snap and lima beans, cabbage, lettuce and endive, peas, peppers, and potatoes.   view more (2008-12-02)

NIST researchers 'all aglow' over new test of toxin strength
A new National Institute of Standards and Technology (NIST) assay using a "glow or no glow" technique may soon help the U.S. Department of Homeland Security (DHS) defend the nation against a spectrum of biological weapons that could be used in a terrorist attack.   view more (2009-06-18)

Scientists design potent anthrax toxin inhibitor
Scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), have engineered a powerful inhibitor of anthrax toxin that worked well in small-scale animal tests.   view more (2006-04-25)

Defining gene's role may lead to prevention of dangerous corn toxin
Discovery that a specific gene is integral to both fungal invasion of corn and development of a potentially deadly toxin in the kernels may lead to ways to control the pathogen and the poison.   view more (2008-03-26)

Technique used commonly in physics finds application in neuroscience
o understand how brain cells release compounds (or transmitters) used when the cells communicate with each other, Vladimir Parpura, associate professor of neuroscience, and Umar Mohideen, professor of physics at UC Riverside, devised a new technique, used commonly in physics, that can be applied now to the study of a wide range of biological... view more... (2006-08-07)

E. coli playing the role of cobra
Moscow researchers have solved the most challenging problem: they made E. coli synthesize one of the most toxic elements of cobra's poison. It was no simpler a task than keeping a terrarium. The scientists' efforts were supported by the Russian Foundation for Basic Research and INTAS. Natural poisons have always been an attraction for researchers,... view more... (2004-05-07)

Whooping cough persistence traced to key toxin
A key toxin associated with whooping cough helps the germs resist the human immune system and infect vaccinated populations.   view more (2005-12-19)

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth
Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research, a journal of the American Association for Cancer Research.    view more (2009-07-30)

Aerosol toxins from red tides may cause long-term health threat
NOAA scientists reported in the current issue of the journal Environmental Health Perspectives that an algal toxin commonly inhaled in sea spray, attacks and damages DNA in the lungs of laboratory rats.   view more (2008-07-10)

Dutch ecologists plea for scientific research to aid risk assessment
A survey among nine prominent Dutch ecologists has identified gaps in knowledge on the potential effects of Bt-crops on food chains and ecosystems. Bt-crops have been modified to express a bacterial gene that codes for a toxin that kills certain groups of insects. The toxin is continuously produced in all plant tissues and target as well as... view more... (2003-08-28)
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