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McMaster University researchers discover zip codes for protein
McMaster scientists are very close to defining small molecule drugs that should be able to redirect the huntingtin protein from accumulating in the wrong place within brain cells, which could potentially translate to a therapy for Huntington's Disease (HD). view more (2007-01-30)
Epsilon4 allele carriers show altered brain activity before onset of Alzheimer's symptoms
Healthy individuals who are at risk of Alzheimer's disease show reduced activity in the hippocampal region of the brain when performing tasks related to forming new memories. view more (2006-01-13)
Epilepsy and brain pathology linked together by the protein ADK
The brain of individuals who suffer from epilepsy is characterized by astrogliosis, a brain pathology evidenced by a complex series of changes in the morphology and function of brain cells known as astrocytes. view more (2008-01-03)
Is brain size linked to two common gene variants?
Human brain size is hereditary, but the genes that influence brain size in healthy people are unknown. view more (2006-05-17)
New brain cells listen before they talk
Newly created neurons in adults rely on signals from distant brain regions to regulate their maturation and survival before they can communicate with existing neighboring cells-a finding that has important implications for the use of adult neural stem cells to replace brain cells lost by trauma or neurodegeneration, Yale School of Medicine... view more... (2007-10-31)
HIV in the nervous system - still a cause for concern?
HIV infection can be controlled with antiretroviral drugs, but it cannot be wiped out. New evidence suggests that low levels of HIV may still lead to long-term brain damage and dementia, scientists heard today (Tuesday 09 April 2002) at the spring meeting of the Society for General Microbiology at the University of Warwick. "There is concern for... view more... (2002-04-02)
A brainy idea 25 years in the making
A discovery made 25 years ago about how the brain controls blood pressure regulation is only now being explored with the help of scientists from the Howard Florey Institute. view more (2007-10-04)
Epilepsy drug may help Alzheimer's patients
A popular epilepsy drug may also be beneficial in patients with Alzheimer's disease (AD), according to a new study to be published on October 27 in the Journal of Experimental Medicine. The anti-seizure drug valproic acid improved memory and reduced brain lesions in mice with an AD-like disease. view more (2008-10-27)
Neurologists with expertise in brain stimulation therapy help Parkinson's patients
Patients with Parkinson's disease who are undergoing a treatment known as deep brain stimulation may benefit from the direct involvement of a neurologist with expertise both in movement disorders and in deep brain stimulation. view more (2006-07-11)
Inflammation may trigger Alzheimer's disease, Saint Louis University findings suggest
The anti-inflammatory drug indomethacin could hold promise as a treatment for Alzheimer's disease, says a Saint Louis University doctor and researcher. view more (2009-07-09)
New neuroimaging analysis technique identifies impact of Alzheimer's disease gene in healthy brains
Brain imaging can offer a window into risk for diseases such as Alzheimer's disease (AD). A study conducted at the University of Kansas School of Medicine demonstrated that genetic risk is expressed in the brains of even those who are healthy, but carry some risk for AD. view more (2009-11-18)
Alzheimer's disease: A new small molecule approach to treatment from UCL
New therapeutic approaches in Alzheimer's disease are urgently needed. Work led by Professor Mark Pepys FRS over more than 20 years has identified a protein known as serum amyloid P component (SAP) as a possible therapeutic target in Alzheimer's disease. view more (2009-04-14)
U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
Researchers from the University of Minnesota Medical School and Brain Sciences Center at the Minneapolis VA Medical Center have identified a noninvasive and painless way to diagnose complex brain diseases. view more (2007-08-23)
Wellcome Trust grant to investigate degenerative brain diseases known as `tauopathies`
Dr Julian Thorpe, head of the Electron Microscopy Lab at the University of Sussex, will be working towards a better understanding of degenerative brain diseases thanks to a £247,000 grant from the Wellcome Trust. He is taking a very close look at a possible contributory cause of nerve cell death in a group of conditions related to... view more... (2002-04-17)
Proteins in urine predict brain damage in laboratory animals
The study dealt with the development and prevention of strokes in particular rats which had spontaneously developed extremely high blood pressure. Such a high blood pressure level leads within a few weeks to damage to the kidneys, heart and brain such that the rats die. The researchers found that brain damage in these rats is always preceded by... view more... (1999-06-21)
Jury still out over risks of heading a soccer ball
Heading the ball in soccer is unlikely to cause brain injury but head to head collisions might, says a leading sports physician in this week’s BMJ. view more (2003-08-12)
Automated MRI technique assists in earlier Alzheimer's diagnosis
An automated system for measuring brain tissue with magnetic resonance imaging (MRI) can help physicians more accurately diagnose Alzheimer's disease at an earlier stage according to a new study published in the July issue of the journal Radiology. view more (2008-06-24)
Researchers discover gene mutations that cause childhood brain cancer
Researchers funded by the Canadian Cancer Society have discovered eight similar genes that, when mutated, appear to be responsible for medulloblastoma - the most common of childhood brain cancers. The findings are published today in the online edition of the journal Nature Genetics. view more (2009-03-09)
Rhode Island Hospital study finds link between obesity, type 2 diabetes and neurodegeneration
New research from Rhode Island Hospital found that obesity and Type 2 Diabetes Mellitus (T2DM) can contribute to mild neurodegeneration with features common with Alzheimer's disease (AD) - the first study to show that obesity can cause neurodegeneration. view more (2008-09-05)
Study links manic depression with brain tissue loss
People with bipolar disorder - or manic depression - suffer from an accelerated shrinking of their brain, researchers at the University of Edinburgh have found. view more (2007-07-20)
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