A genetic factor predicts prognosis in brain tumor patients
PLoS ONE has just published a study which defines a gene locus on chromosome 1 that predicts prognosis of brain tumor patients and may even set the basis for the development of more efficient drugs to combat brain cancer. view more (2007-06-28)
... 1 that predicts prognosis of brain tumor patients and may even set the basis for the development ... more efficient drugs to combat brain cancer. Clinical and basic researchers from the University Hospital Basel, ... gene as candidate gene for brain tumor development. The study was coordinated by Adrian Merlo, neurosurgeon at ... predicts survival in subgroups of brain tumor patients. This gene ...
First of its kind report on how children with brain tumors perform at school
While children who have had brain tumors perform worse in school than healthy kids, grades in foreign language are the most affected and girls have a harder time than boys in getting good grades. view more (2007-07-17)
... While children who have had brain tumors perform worse in school than healthy kids, grades in foreign ... actual grades and subjects of brain tumor survivors have been reported.
"These results will help us identify brain tumor survivors who are at greatest risk for school failure and ... of 300 children with previous brain tumors, which had been treated with surgery or radiation ...
New brain tumor model developed
A collaboration of researchers, led by Dr. Martine Roussel (St. Jude Children's Research Hospital), has developed a novel mouse model of medulloblastoma - the most prevalent malignant pediatric brain tumor. view more (2005-10-31)
... the most prevalent malignant pediatric brain tumor - that the researchers hope will more accurately represent the ... genetic changes involved in human brain tumor development. Their study will be published in the November 15th ... rely on p53 loss for tumorigenesis, though in human patients, only about 10% of people actually ... Dr. Roussel, "so the Pediatric Brain Tumor Program at our ...
Barrow researchers identify a new approach to detect the early progression of brain tumors
Researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center recently participated in a pilot study with the Montreal Neurological Institute that suggests a certain type of MRI scanning can detect when a patient is failing brain tumor treatment before symptoms appear. view more (2008-08-29)
... when a patient is failing brain tumor treatment before symptoms appear. The results of the study pave ... followed patients with recurring malignant brain tumors who were receiving chemotherapy. Patients received scans through an imaging ... researchers to determine if the tumors were responding to treatment early by assessing metabolic changes in a brain tumor, which are easy to detect and appear ...
Fluorescent cancer cells to guide brain surgeons
Gliomas are malignant brain tumors that arise from glial (supporting) cells of the brain. Gliomas are often resistant to chemotherapy. view more (2009-04-06)
Gliomas are malignant brain tumors that arise from glial (supporting) cells of the brain. Gliomas are often resistant to chemotherapy. These tumors grow fine extensions that infiltrate normal brain tissue and, in addition, individual tumor cells can form satellites in surrounding tissue. Therefore, it is ... almost impossible to remove the tumor tissue completely by surgery.
Yet, radical surgical removal of the ...
SEK 20 million for brain tumor research
The M'Īrit and Hans Rausing Charitable Foundation in England has awarded SEK 20 million over five years to a research team at the Faculty of Medicine at Lund University in Sweden. The team is conducting the so-called BRIGTT Project (BRain Immuno Gene Tumor Therapy), which is pursuing laboratory work and clinical research to try to find new methods... view more... (2003-06-25)
... conducting the so-called BRIGTT Project (BRain Immuno Gene Tumor Therapy), which is pursuing laboratory work and clinical research to ... methods of treatment for malignant brain tumors. The research team is led by Professor Leif G. Salford, ... with the malignant form of tumor called malignant glioma using their own tumor cells, in order to stimulate the immune defense system. The ... treatment ...
Fly with brain tumor may shed light on cancer causing genes
A study showing how the expression of genes changes when the brain tissue of fruit flies becomes cancerous is published this week in BMC Genomics. As the function of many of these genes is conserved across evolution, the researchers expect their results will help us to understand why human brain tumors develop. The causes of brain tumor... view more... (2004-04-14)
... of genes changes when the brain tissue of fruit flies becomes cancerous is published this week ... us to understand why human brain tumors develop. The causes of brain tumor development are largely unknown. To investigate this question, researchers from ... healthy flies and those with brain cancer. They found significant changes in the expression levels of ... cancer had mutations in ...
Tumor suppressor gene in flies may provide insights for human brain tumors
In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and become a brain tumor. view more (2009-06-23)
... In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing ... of control and become a brain tumor.
Researchers at Duke-NUS Graduate Medical School in Singapore have found a ... in Singapore have found a tumor-suppressing protein in the fly's brain, with a counterpart in mammals, that can apparently prevent brain tumors from forming.
"Our data explicitly show ...
There goes the neighborhood: Vascular niche nurtures brain tumor stem cells
Self-renewing cancer stem cells (CSCs) comprise only a tiny fraction of most brain tumors, but eliminating them is likely to have a profound impact on the ability of a tumor to survive and grow. view more (2007-01-17)
... a tiny fraction of most brain tumors, but eliminating them is likely to have a profound impact ... on the ability of a tumor to survive and grow. However, CSCs might resist traditional therapies ... small blood vessels associated with brain tumors orchestrate a distinct microenvironment that is critical for maintaining CSCs. ... the CSC population and arrest tumor growth.
Dr. Richard J. ...
Erectile dysfunction drugs allowed more chemotherapy to reach brain tumors in laboratory study
In a study using laboratory animals, researchers found that medications commonly prescribed for erectile dysfunction opened a mechanism called the blood-brain tumor barrier and increased delivery of cancer-fighting drugs to malignant brain tumors. view more (2008-07-29)
... opened a mechanism called the blood-brain tumor barrier and increased delivery of cancer-fighting drugs to malignant brain tumors.
The experiments were conducted at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical ... Neurosurgical Institute and published in Brain Research.
Viagra (sildenafil) and Levitra (vardenafil) are known as PDE5 inhibitors ... the small vessels of the brain play a major role in the blood-brain tumor barrier, which ...
Tumor-killing virus selectively targets diseased brain cells
New findings show that a specialized virus with the ability to reproduce its tumor-killing genes can selectively target tumors in the brains of mice and eliminate them. view more (2008-02-20)
... the ability to reproduce its tumor-killing genes can selectively target tumors in the brains of mice and eliminate them. Healthy brain tissue remained virtually untouched, according to a Feb. 20 report ... a novel way of treating brain cancer in humans.
"Most importantly, this study finds that the virus ... virus can penetrate into the brain, where it even reaches cells that have ...
Patients regain cognitive function after radiation for brain tumors
Patients who suffer from low-grade brain tumors are able to regain normal cognitive function after receiving radiation therapy to shrink their tumor. view more (2005-11-16)
Patients who suffer from low-grade brain tumors are able to regain normal cognitive function after receiving radiation ... radiation therapy to shrink their tumor, according to a study published in the November 15, 2005, ... radiation therapy to treat their brain tumor, the 20 patients studied were submitted to a battery of ... suggest that the patients with brain tumors perform below average ...
USC researchers develop new drug to target tumor cells and blood vessels
Researchers at the University of Southern California have identified a new drug compound that appears to target tumor cells and surrounding blood vessels without the negative side effects typically associated with Cox-2 inhibitors. view more (2009-04-20)
... effective as long-term therapy for brain tumors
Researchers at the University of Southern California have identified a new ... compound that appears to target tumor cells and surrounding blood vessels without the negative side effects ... appears to have a strong anti-tumor effect while also attacking the vasculature that provides the blood ... the blood supply necessary for tumor growth, according to data presented ...
Novel 3-D cell culture model shows selective tumor uptake of nanoparticles
A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists. view more (2007-08-23)
... drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by ... Experimental Biology and Medicine.
Therapy for brain cancers is particularly difficult for a number of reasons, including ... getting sufficient drug to the tumor and selectivity of drug action. "We are working on a ... nanoparticles more effective.
"The interaction of tumor ...
Tumor cells evade death through autophagy
Autophagy is a cellular process that enables cells to turnover their contents, something that they do frequently. Autophagy is initiated in tumor cells by chemotherapy and radiation, but it is not known if this contributes to tumor cell death or helps tumor cells survive the anti-cancer therapy. view more (2007-01-19)
... frequently. Autophagy is initiated in tumor cells by chemotherapy and radiation, but it is not known ... known if this contributes to tumor cell death or helps tumor cells survive the anti-cancer therapy. However, in a study using ... represents a survival mechanism for tumor cells treated with agents that initiate tumor cell death by a process known as apoptosis.
In the ... | 
