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Cellular target may prove useful in treating deadly brain tumors
Duke University researchers have identified a receptor on the surface of cells that may give them another avenue of attack against glioblastoma, the most common and most deadly type of brain cancer. view more (2009-04-06)
Researchers break chain of biochemical events that brain cancer cells use to evade therapy
In their quest to find and exploit vulnerabilities in the natural armor that protects malignant brain tumors from destruction, researchers have found a way to decrease the cells resistance to therapies that are designed to trigger cell death. view more (2006-02-06)
Breast cancer : Discovery of a new tumor marker
At the Curie Institute in Paris, CNRS researchers have discovered a new proliferation marker : the CAF-1 complex. Since deregulated cell proliferation is one of the most characteristic features of tumor cells, this discovery represents a breakthrough in the cancer field. The researchers from the Curie Institute have already validated the use of... view more... (2004-03-30)
A new therapeutic option for human hepatocyte cancer
p53-impaired tumors may be particularly suitable to parvovirus H-1-induced therapy. Although the p53 deficiency in tumors may induce resistance to chemotherapeutic agents, this will not affect the tumor cell susceptibility to H-1 PV-induced oncolytic infections. view more (2008-09-24)
Sensitizing tumor response to cancer therapy
Two forms of skin and brain cancer respond very poorly to chemotherapy and radiation: melanoma and glioblastoma multiforme brain cancer. view more (2009-08-06)
Hopkins geneticist discovers mutations in cancer cells that suggest new forms of treatment
Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors, a discovery that could pave the way for more effective cancer treatments. view more (2005-09-27)
Massive necrosis after trans-catheter treatment is more common in the presence of tumor capsule
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Prognosis of patients with HCC complicating cirrhosis mainly depends on the tumor growth, progression of the underlying liver disease and the effectiveness of antitumoral treatment. view more (2007-11-26)
Jefferson oncologists show less radiation just as effective in fighting brain tumor, saving hearing
Radiation oncologists at the Kimmel Cancer Center at Thomas Jefferson University and Thomas Jefferson University Hospital in Philadelphia have found that giving less radiation than usual is just as effective against a benign but potential devastating brain tumor called an acoustic schwannoma, and better yet, might save more of the patient's... view more... (2006-11-08)
Post-pregnancy events promote breast tumor metastasis
Changes in the tissue environment of the breast that occur after pregnancy promote the metastasis of breast tumor cells. view more (2006-02-03)
Mayo Clinic researchers discover and manipulate molecular interplay that moves cancer cells
Based on research that reveals new insight into mechanisms that allow invasive tumor cells to move, researchers at the Mayo Clinic campus in Florida have a new understanding about how to stop cancer from spreading. A cancer that spreads elsewhere in the body, known as metastasis, is the process that most often leads to death from the disease. view more (2009-03-30)
Tulane pioneers novel ovarian cancer treatment
The Tulane University Section of Hematology and Medical Oncology is investigating a novel treatment for ovarian cancer by using intravenous Ontak to deplete harmful cells that inhibit the body's natural immune response to fight cancer. Ovarian cancer is the fifth leading cancer killer of women in the United States. view more (2005-07-18)
Study identifies new tumor suppressor
A protein called HLJ1 may work as a novel tumor suppressor in non-small-cell lung carcinoma. view more (2006-06-21)
Brown Chemists Create Cancer-Detecting Nanoparticles
A team led by a Brown University chemist has created the smallest iron oxide nanoparticles to date for cancer detection by magnetic resonance imaging (MRI). The magnetic nanoparticles operate like tiny guided missiles, seeking and attaching themselves to malignant tumor cells. Once they bind, the particles emit stronger signals that MRI scans can... view more... (2008-05-28)
New insights into the regulation of PTEN tumor suppression function
The PTEN tumor suppressor gene controls numerous biological processes including cell proliferation, cell growth and death. But PTEN is frequently lost or mutated; in fact, alteration of the gene is so common among various types of human cancer that PTEN has become one of the most frequently mutated of all tumor suppressors. view more (2008-08-21)
U of M researchers discover compounds to shrink tumors
Researchers at the University of Minnesota have developed novel anti-cancer drugs to treat solid tumors. These "small molecules" belong to a class of pharmaceutical agents called anti-angiogenics. view more (2006-07-06)
Proteins in urine predict brain damage in laboratory animals
The study dealt with the development and prevention of strokes in particular rats which had spontaneously developed extremely high blood pressure. Such a high blood pressure level leads within a few weeks to damage to the kidneys, heart and brain such that the rats die. The researchers found that brain damage in these rats is always preceded by... view more... (1999-06-21)
High-Intensity Ultrasound May Launch an Attack on Cancer, Wherever it Lurks
An intense form of ultrasound that shakes a tumor until its cells start to leak can trigger an "alarm" that enlists immune defenses against the cancerous invasion, according to a study led by researchers at Duke University's Pratt School of Engineering. view more (2007-08-08)
Are tumors causing stricture of bile duct always malignant?
The benign biliary tract tumor is rarely found in clinical practice. One case of bile duct adenomyoma was recently reported in the January 28 issue of the World Journal of Gastroenterology. view more (2008-02-22)
Bone drug could help prevent the spread of breast cancer
Maintaining bone density could be a key to decreasing the spread of cancer in women with locally advanced breast cancer, according to research at Washington University School of Medicine in St. Louis. view more (2008-05-19)
MicroRNA-mediated metastasis suppression
Metastases are responsible for over 90% of cancer deaths. In the upcoming issue of G&D, Dr. Robert Weinberg (MIT) and colleagues lend molecular insight into how microRNAs suppress tumor metastasis. view more (2009-10-29)
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