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NIH researchers identify key factor that stimulates brain cancer cells to spread
Researchers funded by the National Institutes of Health have found that the activity of a protein in brain cells helps stimulate the spread of an aggressive brain cancer called glioblastoma multiforme (GBM). view more (2009-08-19)
Intra-arterial combination chemotherapy induces long-term survival for hepatocellular carcinoma
Portal venous tumor thrombus (PVTT) is a crucial factor that can worsen the prognosis of patients with hepatocellular carcinoma (HCC). view more (2007-10-18)
Cancer gene drives pivotal decision in early brain development
A gene linked to pediatric brain tumors is an essential driver of early brain development, researchers at Washington University School of Medicine in St. Louis have found. view more (2007-11-14)
Rheb's role in cancer
Two independent papers in the August 15th issue of G&D identify the Rheb GTPase as a novel oncogene and a promising new chemotherapeutic target. view more (2008-08-15)
New pathway could present an intervention point for cancer treatment
A new cellular pathway leads to destruction of a protein that promotes growth of breast, prostate and similar cancers and could provide a new avenue through which to pursue treatment of such diseases. view more (2006-01-27)
During exercise, the human brain shifts into high gear on 'alternative energy'
Alternative energy is all the rage in major media headlines, but for the human brain, this is old news. According to a study by researchers from Denmark and The Netherlands published in the October 2008 print issue of The FASEB Journal, the brain, just like muscles, works harder during strenuous exercise and is fueled by lactate, rather than... view more... (2008-10-01)
Genes set scene for metastasis
Biologists at Memorial Sloan-Kettering Cancer Center (MSKCC) have identified a set of genes expressed in human breast cancer cells that work together to remodel the network of blood vessels at the site of the primary tumor. view more (2007-04-12)
Rate of secondary cancers increases over years after treatment for childhood leukemia
Survivors of acute lymphoblastic leukemia have a significantly increased risk of secondary cancers developing over 30 years after leukemia treatment when compared to the general population. view more (2007-03-21)
Finding out which parts of the brain do what
Ever since the Greeks proposed that different parts of the brain housed different parts of the ‘soul’, mankind has tried to discover where our mental functions are located. This evening, Thursday 22 February, in a public lecture at the Royal Society, 6 Carlton House Terrace, London SW1Y 5AG, Professor Alan Cowey FRS of the University... view more... (2001-02-15)
Surgery not necessary for most late-stage colorectal cancers
A new study shows that a large majority of patients who present with advanced colorectal cancer that has spread to other organs (stage IV) don't require immediate surgery to remove the primary tumor in the colon. view more (2009-06-01)
Anti-angiogenesis treatment improves hearing in some NF2 patients
Treatment with the angiogenesis inhibitor bevacizumab improved hearing and alleviated other symptoms in patients with neurofibromatosis type 2 (NF2). view more (2009-07-09)
Antitumor agent under the microscope
Mechanical stabilization of DNA keeps tumor cells in check Cisplatin is one of the most widely employed cancer medications. As with many other chemotherapy agents, the mechanism by which it works has not been fully researched. Now, thanks to Munich physicists Hermann E. Gaub, Rupert Krautbauer, and Hauke Clausen-Schaumann, an important step toward... view more... (2000-10-30)
Mind over matter: SH2B1 in the brain regulates obesity
Obesity is one of the main risk factors for developing type II diabetes. Previous studies have shown that mice lacking a protein known as SH2B1 throughout their body are obese and develop diabetes. view more (2007-01-19)
A novel mechanism of action for anti-tumor agent, CA4P
Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months. view more (2005-10-07)
What is the influence of tumor removal on the serum level of carbohydrate's antibody?
Cancer immune surveillance is considered to be important in the anti-tumor protection of the host. The growing tumor escapes the immune control under the immunosuppressive conditions. view more (2008-10-08)
RNA splicing factor implicated in ovarian tumor cell growth
An RNA-binding protein that is overproduced in ovarian cancer may present a new target for diagnosis or treatment of ovarian and other cancers, according to researchers at the University of Illinois at Chicago. view more (2007-04-10)
UAB Researchers Draft 3-D Protein Map
A new three-dimensional computer protein map is helping researchers at the University of Alabama at Birmingham (UAB) unravel the biological pathways that control brain-cell death after a stroke. view more (2009-06-25)
UCLA cancer researchers develop model that may help identify cancer stem cells
Researchers at UCLA's Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers. view more (2009-06-16)
Nanoparticles + light = dead tumor cells
Medical physicists at the University of Virginia have created a novel way to kill tumor cells using nanoparticles and light. view more (2008-07-30)
Study suggests brain tumors need treatment with multiple 'targeted' drugs
Researchers at Dana-Farber Cancer Institute have shown that several, rather than just one, cell-growth switches are simultaneously overactive in many brain tumors and other solid tumors, explaining why treatment with just a single "targeted" switch-blocking drug often yields disappointing results. view more (2007-09-14)
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