Breast Tumor Current Events | Breast Tumor News
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T-beta-RIII joins the fight against breast cancer
Although the soluble factor TGF-beta has been shown to suppress the growth of tumor cells in the early stages of breast cancer, high levels of TGF-beta during the later stages of the disease are associated with a poor outcome. view more (2006-12-08)
Identifying the potential for tamoxifen resistance in patients
Tamoxifen is a widely used and highly successful drug in the treatment of breast cancer, though resistance to tamoxifen is still a concern in recurrent disease (affecting 25-35% of patients), since therapy resistant metastatic tumor cells are a major cause of death. view more (2009-06-11)
Genes set scene for metastasis
Biologists at Memorial Sloan-Kettering Cancer Center (MSKCC) have identified a set of genes expressed in human breast cancer cells that work together to remodel the network of blood vessels at the site of the primary tumor. view more (2007-04-12)
Post-pregnancy events promote breast tumor metastasis
Changes in the tissue environment of the breast that occur after pregnancy promote the metastasis of breast tumor cells. view more (2006-02-03)
USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought. view more (2006-10-09)
Colorful spy tactics track live cells supporting cancerous tumors
A new advance in cellular imaging is allowing scientists to better understand the movement of cells in the area around tumors, also known as the tumor microenvironment. view more (2008-09-17)
Gene linked to lower breast cancer risk
Dr. Uwe Langsenlehner and colleagues from Medical University Graz in Austria showed that a specific genetic variation in a cytokine gene is associated with lower breast cancer risk. view more (2005-06-06)
Study links nicotine with breast cancer growth and spread
A study published in Cancer Research, a journal of the American Association for Cancer Research, suggests a possible role for nicotine in breast tumor development and metastases. view more (2008-10-15)
Sentinel lymph node biopsy is associated with breast cancer rates
The incidence of some early stage metastatic breast cancers is increasing, but this finding is likely explained by changes in clinical practice, according to a study published online June 26 in the Journal of the National Cancer Institute. view more (2007-06-27)
Breast cancer etiology may vary by subtype
Women's reproductive and lifestyle characteristics can be linked to different invasive breast cancer subtypes. Data on 2544 breast cancer cases, presented in the open access journal Breast Cancer Research, suggests that traditional risk factors for development of the condition are associated with different kinds of tumor. view more (2009-05-22)
New biomarker predicts effectiveness of breast cancer drugs
University of Cincinnati (UC) researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer. view more (2006-12-08)
Early predictor of breast cancer aggressiveness
Physicians may be able to make early decisions on the best treatment for breast cancer, thanks to research published in Breast Cancer Research today. A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive, researchers found. Measuring the activity of the ALCAM gene in... view more... (2004-06-24)
MicroRNA-mediated metastasis suppression
Metastases are responsible for over 90% of cancer deaths. In the upcoming issue of G&D, Dr. Robert Weinberg (MIT) and colleagues lend molecular insight into how microRNAs suppress tumor metastasis. view more (2009-10-29)
Chemotherapy and tamoxifen reduce risk of second breast cancer
Among breast cancer patients, both chemotherapy and tamoxifen independently reduced the risk of developing a second cancer in the other breast, according to a study published online December 25 in the Journal of the National Cancer Institute. The risk reduction persisted for at least 10 and 5 years, respectively. view more (2007-12-26)
Lymph nodes harbor information on whether breast cancer will recur
Breast cancer often spreads through the lymph nodes in the arm pits (so-called axillary lymph nodes), and whether these lymph nodes are tumor-free or contain small metastases is an important factor in the decision of how aggressively to treat a patient. view more (2005-09-06)
Bone drug could help prevent the spread of breast cancer
Maintaining bone density could be a key to decreasing the spread of cancer in women with locally advanced breast cancer, according to research at Washington University School of Medicine in St. Louis. view more (2008-05-19)
Molecular pathway linked to breast cancer recurrence
A study published in the September issue of Cancer Cell provides new evidence for a genetic pathway that is involved in the recurrence of breast cancer and identifies a potential target for development of new anticancer therapeutics. view more (2005-09-20)
MRI more accurately determines cancer spread into breast ducts
MRI is better than MDCT for determining if and how far breast cancer has spread into the breast ducts and should be used before patients receive breast conserving therapy, a new study shows. view more (2006-09-05)
Promising advance in breast cancer research
Two new drugs, when combined, killed up to 75 percent of breast cancer tumor cells in mice and suppressed the regrowth of tumors, according to researchers at the Virginia Commonwealth University Massey Cancer Center. view more (2005-11-15)
Scripps research scientists show protein accelerates breast cancer progression in animal models
These new findings could lead to a better understanding of the molecular pathogenesis of breast cancer and focus attention on PTN and its signaling pathway as possible targets for new cancer therapies. view more (2007-06-21)
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