Cancer Cell Current Events | Cancer Cell News | 11
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Chemosensitivity of cancer cells depends on their protein dependency
Two different anti-apoptotic proteins support cancer cell survival via an identical mechanism, yet differ in their sensitivity to chemotherapeutic drugs, report Brunelle et al. The study will be published online October 26, 2009 and in the November 2, 2009 print issue of the Journal of Cell Biology (JCB). view more (2009-10-26)
OHSU Cancer Institute research discovery opens new window to understanding chronic myeloid leukemia
Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML). view more (2007-12-10)
Treatments have same target, different responses for lung cancer patients with genetic mutation
The gene mutation that identifies the lung cancer patients most likely to respond to the drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux). view more (2005-08-17)
Protein can help cells or cause cancer, Purdue researcher finds
A Purdue University scientist has discovered a key process in cell growth that can lead to the formation of tumors. view more (2009-07-08)
A sticky business -- how cancer cells become more 'gloopy' as they die
The viscosity, or 'gloopiness', of different parts of cancer cells increases dramatically when they are blasted with light-activated cancer drugs, according to new images that provide fundamental insights into how cancer cells die, published in Nature Chemistry today (15 March). view more (2009-03-16)
USC study in Nature Genetics supports a stem cell origin of cancer
Researchers at the University of Southern California (USC) recently made significant strides toward settling a decades-old debate centering on the role played by stem cells in cancer development. view more (2007-01-10)
Molecular 'clock' could predict risk for developing breast cancer
A chemical reaction in genes that control breast cancer provides a molecular clock that could one day help researchers more accurately determine a woman's risk for developing breast cancer and provide a new approach for treatment, UT Southwestern Medical Center researchers have found. view more (2008-05-14)
Mayo Clinic Researchers Find That Protein Believed to Protect Against Cancer Has a Mr. Hyde Side
In a biological rendition of fiction's Strange Case of Dr. Jekyll and Mr. Hyde, researchers from the Mayo Clinic campus in Florida and Harvard Medical School have found that a protein thought to protect against cancer development can actually spur the spread of tumors. view more (2009-09-04)
Synthetic molecules hold promise for new family of anti-cancer drugs
Synthetic molecules designed by two Hebrew University of Jerusalem researchers have succeeded in reducing and even eliminating the growth of human malignant tissues in mice, while having no toxic effects on normal tissue. view more (2008-06-05)
Protein binds whenever it can
Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge is important for gaining a better understanding of... view more... (2003-06-24)
U-M researchers discover new genes that fuse in cancer
Using new technologies that make it easier to sequence the human genome, researchers at the University of Michigan Comprehensive Cancer Center have identified a series of genes that become fused when their chromosomes trade places with each other. view more (2009-01-12)
New study gives further hope that vitamin D can fight breast cancer
Vitamin D may help curb breast cancer progression, according to a study published today in the Journal of Clinical Pathology. view more (2006-10-17)
Cutaneous T-Cell Lymphoma On The Rise, VA/Brown Research Shows
Cutaneous T-cell lymphoma, a rare and mysterious cancer, is on the rise, according to the first nationwide study of the disease in a decade. view more (2007-07-17)
Cellular molecule spurs growth of prostate cancer
University of North Carolina at Chapel Hill scientists have identified a molecule that stimulates the aggressive growth of prostate cancer. view more (2005-11-29)
New telomere discovery could help explain why cancer cells never stop dividing
A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA. view more (2007-10-05)
Curcumin may inhibit nicotine-induced activation of head and neck cancers
Curcumin, the compound that gives curry powder its yellow/orange color, may inhibit the adverse effects of nicotine in patients with head and neck cancer who continue to smoke. view more (2009-10-05)
Statin plus cancer drug deliver combo punch to brain cancer cells
Building on newly discovered genetic threads in the rich tapestry of biochemical signals that cause cancer, a Johns Hopkins Kimmel Cancer Center team has dramatically killed brain cancer cells by blocking those signals with a statin and an experimental antitumor drug. view more (2007-01-19)
Bowel cancer indicator should lead to better treatment
STEM cell scientists have developed a more accurate way of identifying aggressive forms of bowel cancer, which should eventually lead to better treatment and survival rates. view more (2008-08-20)
SCIENTISTS TAKE A STEP CLOSER TO UNDERSTANDING BREAST CANCER GENEWorld first for Imperial Cancer Research Fund
Scientists from the Imperial Cancer Research Fund are the first in the world to solve the structure of an important region of a protein molecule made by the XRCC1 gene which has a role in human DNA repair. The same region is also found in the BRCA1 gene which is involved in breast cancer. Their findings now explain why some genetic changes can... view more... (1998-11-03)
VCU Massey Cancer Center Spearheads Novel Clinical Study for Lymphoma Patients
The Virginia Commonwealth University Massey Cancer Center recently opened a National Cancer Institute (NCI)-sponsored, phase II clinical study for certain sub-types of non-Hodgkin's lymphoma. view more (2008-09-03)
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