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Cancer Cell Current Events | Cancer Cell News | 6

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USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought.   view more (2006-10-09)

Vitamin C supplements may reduce benefit from wide range of anti-cancer drugs
In pre-clinical studies, vitamin C appears to substantially reduce the effectiveness of anticancer drugs, say researchers at Memorial Sloan-Kettering Cancer Center.   view more (2008-10-01)

Faulty cell cycle checkpoints linked to lung cancer risk in African-Americans
Faulty cell cycle "checkpoints" that fail to respond to DNA damage effectively may contribute to the high incidence of lung cancer in African-Americans.   view more (2005-10-17)

Hopkins scientists find cells responsible for bladder cancer's spread
Johns Hopkins scientists have tracked down a powerful set of cells in bladder tumors that seem to be primarily responsible for the cancer's growth and spread using a technique that takes advantage of similarities between tumor and organ growth.   view more (2009-08-07)

Analysis shows combining sorafenib with carboplatin/paclitaxel adds no benefit in lung cancer
A clinical trial evaluating the benefit of adding the drug sorafenib to the combination of carboplatin/paclitaxel chemotherapy for lung cancer patients has been stopped based on results from an interim analysis, after an independent data monitoring committee concluded that the study would not meet its primary endpoint of improved overall survival.   view more (2008-04-28)

Study shows drug combination improves outcome for advanced non-small cell lung cancer
A new, international study found that the combination of two drugs delays disease progression for patients with advanced non-small cell lung cancer (NSCLC).   view more (2009-06-01)

When cancer cells can't let go
Like a climber scaling a rock face, a migrating cancer cell has to keep a tight grip on the surface but also let go at the right moment to move ahead.   view more (2009-04-14)

Inhibitor of novel cancer target, LPAAT-beta, demonstrates selective anti-cancer effects in animal cancer models
Frankfurt, Germany: In a plenary session at the Symposium on Molecular Targets and Cancer Therapeutics, Dr Jack W. Singer, M.D. and Research Program Chairman of Cell Therapeutics, Inc. (CTI) today (Thursday 21 November) presented data from preclinical studies on a novel cancer target LPAAT-beta[1] in cultured cells and in preliminary animal... view more... (2002-11-17)

Cancer cells 'reprogram' energy needs to grow and spread, study suggests
Studying a rare inherited syndrome, researchers at Johns Hopkins have found that cancer cells can reprogram themselves to turn down their own energy-making machinery and use less oxygen, and that these changes might help cancer cells survive and spread.   view more (2007-05-08)

Breast cancer : Discovery of a new tumor marker
At the Curie Institute in Paris, CNRS researchers have discovered a new proliferation marker : the CAF-1 complex. Since deregulated cell proliferation is one of the most characteristic features of tumor cells, this discovery represents a breakthrough in the cancer field. The researchers from the Curie Institute have already validated the use of... view more... (2004-03-30)

Stress may help cancer cells resist treatment, research shows
Scientists from Wake Forest University School of Medicine are the first to report that the stress hormone epinephrine causes changes in prostate and breast cancer cells that may make them resistant to cell death.   view more (2007-04-11)

Human cells secrete cancer-killing protein, UK study finds
Human cells are able to secrete a cancer-killing protein, scientists at the University of Kentucky's Markey Cancer Center have found.   view more (2009-07-24)

DACH1 a key protein for tumor suppression in ER+ breast cancer
Researchers from the Kimmel Cancer Center at Jefferson have identified a protein relationship that may be an ideal treatment target for ER+ breast cancer.   view more (2009-07-15)

Double binding sites on tumor target may provide future combination therapy
Researchers from the University of Pennsylvania School of Medicine and colleagues at Merck Serono Research in Germany have found that two drugs bind to receptor sites on some tumors in different places at the same time, suggesting the possibility of a new combination therapy for certain types of cancer.   view more (2008-04-09)

Cancer stem cells: know thine enemy
Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer.   view more (2007-12-26)

U-M researchers link pathway to breast cancer stem cells
A gene well known to stop or suppress cancer plays a role in cancer stem cells, according to a new study from the University of Michigan Comprehensive Cancer Center. The researchers found that several pathways linked to the gene, called PTEN, also affected the growth of breast cancer stem cells.   view more (2009-06-02)

University of Kent Appoints Leading Cancer Researcher
One of the UKˇ¦s leading cancer researchers, Professor Bill Gullick, is to become the University of Kent at Canterburyˇ¦s (UKC) new Chair in Cancer Biology from 1 January 2000. Currently Principal Scientist at the Imperial Cancer Research Fund (ICRF) Molecular Oncology Unit in Hammersmith, and Professor of Molecular Oncology at the Imperial... view more... (1999-11-15)

Cancer patients monitor fatigue in real time
Fatigue is one of the most common and distressing symptoms cancer patients experience during chemotherapy and radiation treatment, but it's difficult for health care professionals to accurately assess its severity.   view more (2007-05-04)

Rewind, please: Nature paper shows that cell division is reversible
Gary J. Gorbsky, Ph.D., a scientist with the Oklahoma Medical Research Foundation, has found a way to reverse the process of cell division.   view more (2006-04-13)

First compound that specifically kills cancer stem cells found
The cancer stem cells that drive tumor growth and resist chemotherapies and radiation treatments that kill other cancer cells aren't invincible after all.   view more (2009-08-14)
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