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USC study in Nature Genetics supports a stem cell origin of cancer
Researchers at the University of Southern California (USC) recently made significant strides toward settling a decades-old debate centering on the role played by stem cells in cancer development.   view more (2007-01-10)

Molecular 'clock' could predict risk for developing breast cancer
A chemical reaction in genes that control breast cancer provides a molecular clock that could one day help researchers more accurately determine a woman's risk for developing breast cancer and provide a new approach for treatment, UT Southwestern Medical Center researchers have found.   view more (2008-05-14)

Synthetic molecules hold promise for new family of anti-cancer drugs
Synthetic molecules designed by two Hebrew University of Jerusalem researchers have succeeded in reducing and even eliminating the growth of human malignant tissues in mice, while having no toxic effects on normal tissue.   view more (2008-06-05)

Protein binds whenever it can
Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge... view more (2003-06-24)

Cutaneous T-Cell Lymphoma On The Rise, VA/Brown Research Shows
Cutaneous T-cell lymphoma, a rare and mysterious cancer, is on the rise, according to the first nationwide study of the disease in a decade.   view more (2007-07-17)

New study gives further hope that vitamin D can fight breast cancer
Vitamin D may help curb breast cancer progression, according to a study published today in the Journal of Clinical Pathology.   view more (2006-10-17)

Cellular molecule spurs growth of prostate cancer
University of North Carolina at Chapel Hill scientists have identified a molecule that stimulates the aggressive growth of prostate cancer.   view more (2005-11-29)

New telomere discovery could help explain why cancer cells never stop dividing
A group working at the Swiss Institute for Experimental Cancer Research (ISREC) in collaboration with the University of Pavia has discovered that telomeres, the repeated DNA-protein complexes at the end of chromosomes that progressively shorten every time a cell divides, also contain RNA.   view more (2007-10-05)

Statin plus cancer drug deliver combo punch to brain cancer cells
Building on newly discovered genetic threads in the rich tapestry of biochemical signals that cause cancer, a Johns Hopkins Kimmel Cancer Center team has dramatically killed brain cancer cells by blocking those signals with a statin and an experimental antitumor drug.   view more (2007-01-19)

Bowel cancer indicator should lead to better treatment
STEM cell scientists have developed a more accurate way of identifying aggressive forms of bowel cancer, which should eventually lead to better treatment and survival rates.   view more (2008-08-20)

SCIENTISTS TAKE A STEP CLOSER TO UNDERSTANDING BREAST CANCER GENEWorld first for Imperial Cancer Research Fund
Scientists from the Imperial Cancer Research Fund are the first in the world to solve the structure of an important region of a protein molecule made by the XRCC1 gene which has a role in human DNA repair. The same region is also found in the BRCA1 gene which is involved in breast cancer. Their... view more (1998-11-03)

VCU Massey Cancer Center Spearheads Novel Clinical Study for Lymphoma Patients
The Virginia Commonwealth University Massey Cancer Center recently opened a National Cancer Institute (NCI)-sponsored, phase II clinical study for certain sub-types of non-Hodgkin's lymphoma.   view more (2008-09-03)

RNA splicing factor implicated in ovarian tumor cell growth
An RNA-binding protein that is overproduced in ovarian cancer may present a new target for diagnosis or treatment of ovarian and other cancers, according to researchers at the University of Illinois at Chicago.   view more (2007-04-10)

Study proposes new theory of how viruses may contribute to cancer
A new study suggests that viruses may contribute to cancer by causing excessive death to normal cells while promoting the growth of surviving cells with cancerous traits.   view more (2007-10-24)

Relationship between environmental stress and cancer elucidated
One way environmental stress causes cancer is by reducing the activity level of an enzyme that causes cell death, researchers say.   view more (2007-11-06)

Study establishes new class of cancer-causing genes
Over the past few years, scientists have discovered that a new class of genetic regulators called "microRNAs" influences normal human growth and development. Now, researchers have found that microRNAs also play an important role in human cancer.   view more (2005-06-08)

Secrets of cellular signaling shed light on new cancer stem cell therapies
By revealing the inner workings of a common cell-to-cell signaling system, University of Michigan biologists have uncovered new clues about mysterious and contentious creatures called cancer stem cells.   view more (2008-04-10)

The clue of genomic instability in breast cancer
New research has shown, using human tissue biopsies - a hypothesis that until now could only be argued indirectly using cell cultures - that the significant increase in genomic "disorder" that is associated with breast cancer occurs in the transition between the typical hyperplasia and the in situ... view more (2004-09-07)

Protein found to shield pancreatic cancer cells from self-destruction
An overexpressed protein protects human pancreatic cancer cells from being forced to devour themselves, removing one of the body's natural defenses against out-of-control cell growth.   view more (2007-03-20)

Doctors conclude temsirolimus is effective new treatment for advanced renal cell carcinoma
The results of a phase III, randomized clinical study involving patients with advanced renal cell carcinoma and poor prognostic features show temsirolimus improved overall survival when compared to the current treatment for this stage of disease.   view more (2007-05-31)

Experimental anti-cancer synthetic molecule targets tumor cell growth and angiogenesis
A recent study conducted by three French CNRS (Centre National de la Recherche Scientifique) laboratories describes a new candidate anti-cancer drug, named HB-19.   view more (2008-06-18)

Study shows how daughter is different from mother
The mother-daughter relationship can be difficult to understand. Why are the two so different? Now a Northwestern University study shows how this happens. In yeast cells, that is.   view more (2008-08-19)

New algorithm matches any tumor cells to best possible anti-cancer treatments
Cancer patients don't have time to waste. Many go through several different treatments, however, to find one that is more effective against their particular type of tumor.   view more (2007-07-24)

Variant of vitamin D receptor gene linked to melanoma risk
A new analysis indicates an association between a gene involved in vitamin D metabolism and skin cancer. Published in the November 1, 2008 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study suggests that individuals with certain variants in a vitamin D-related gene,... view more (2008-09-22)

Jefferson scientists uncover role of cancer stem cell marker: controlling gene expression
Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have made an extraordinary advance in the understanding of the function of a gene previously shown to be part of an 11-gene "signature" that can predict which tumors will be aggressive and likely to spread.   view more (2008-01-18)
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