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Isolation of a new gene family essential for early development
Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of... view more (2007-08-23)

Study demonstrates how gene variant may contribute to cancer development
A relatively common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer, and give cancer cells a growth advantage, according to a study in the October 5 issue of JAMA.   view more (2005-10-05)

New inhibitor has potential as cancer drug
Laboratory experiments have previously shown that cancer cells overproduce an enzyme, heparanase, which splits the body's own polysaccharide heparan sulfate into shorter fragments.   view more (2007-10-23)

Going from ulcers to cancer
Researchers have uncovered a big clue as to why some of the bacteria that cause stomach ulcers pose a greater risk for serious problems like stomach cancer than others; it turns out these bacteria can exploit the surrounding stomach cells to protect them from the immune system.   view more (2008-08-25)

Scripps research scientists show protein accelerates breast cancer progression in animal models
These new findings could lead to a better understanding of the molecular pathogenesis of breast cancer and focus attention on PTN and its signaling pathway as possible targets for new cancer therapies.   view more (2007-06-21)

Head and neck cancer vaccine targets proteins to create immune response
Most attempts to create therapeutic cancer vaccines are based on custom-made approaches that use a patient's own tumor cells to generate a strong immune response against cancer. However, developing these kinds of personalized vaccines is time-consuming, expensive and often impractical.   view more (2007-04-18)

Can pomegranates prevent prostate cancer? A new study offers promise
The juice of the pomegranate, say researchers at University of Wisconsin Medical School, shows major promise to combat prostate cancer-the most common invasive cancer and the second-leading cause of cancer death in American men.   view more (2005-09-27)

Scientists identify cells responsible for relapse after treatment in common childhood cancer
Approximately 20% of children with ALL will experience a relapse of their disease following treatment. Of these, most will never be cured.   view more (2007-03-29)

Tug-of-cell war
Researchers at the School of Life Sciences, University of Dundee have made an exciting new discovery on how cells regulate themselves and prevent cancer as reported in Nature tomorrow (Wednesday). Dr Tomo Tanaka and his team members, Drs Hilary Dewar and Kozo Tanaka have uncovered a tug of war that... view more (2004-02-10)

Common viruses may cause cancer
In some cases, the fusion of human cells is a normal process that leads, for instance, to the formation of muscle and bone. Viral infections can also cause cell fusion, but cells fused by viruses are widely considered to be harmless because they are generally believed to die without consequences... view more (2005-11-09)

Aspirin discovery may improve cancer treatments
Salicylates, including aspirin, are used to treat a range of inflammatory conditions and can be used to prevent diseases such as cancer, but the way aspirin works is not yet fully understood.   view more (2007-04-06)

Cancer Cell Detection Technology Wins Kaye Award For Hebrew University Researchers
A unique technology for optoelectronic detection of the presence of cancer cells has been developed at the Hebrew University of Jerusalem by a team of researchers headed by Itamar Willner, Enrique Berman Professor of Solar Energy at the Institute of Chemistry. The technology detects the presence... view more (2004-06-20)

Researchers at Vanderbilt-Ingram Cancer Center uncover clue to explain invasive brain tumors
Researchers at the Vanderbilt-Ingram Cancer Center have uncovered a clue to explain the invasive nature of an aggressive kind of brain tumor called glioblastoma multiforme, or gliomas.   view more (2006-01-12)

Inhibitor of novel cancer target, LPAAT-beta, demonstrates selective anti-cancer effects in animal cancer models
Frankfurt, Germany: In a plenary session at the Symposium on Molecular Targets and Cancer Therapeutics, Dr Jack W. Singer, M.D. and Research Program Chairman of Cell Therapeutics, Inc. (CTI) today (Thursday 21 November) presented data from preclinical studies on a novel cancer target LPAAT-beta[1]... view more (2002-11-17)

Breast stem cells have features similar to 'basal' tumors
The most aggressive form of breast cancer may originate from breast stem cells that have undergone genetic mishaps.   view more (2006-07-20)

Study reveals mechanism for cancer-drug resistance
Using the worm Caenorhabditis elegans, researchers at UT Southwestern Medical Center have discovered a mechanism by which cancer cells become resistant to a specific class of drugs.   view more (2006-10-11)

Bone drug could help prevent the spread of breast cancer
Maintaining bone density could be a key to decreasing the spread of cancer in women with locally advanced breast cancer, according to research at Washington University School of Medicine in St. Louis.   view more (2008-05-19)

UGA study finds common component of fruits, vegetables kills prostate cancer cells
A new University of Georgia study finds that pectin, a type of fiber found in fruits and vegetables and used in making jams and other foods, kills prostate cancer cells.   view more (2007-08-21)

UCL study shows beans beat cancer
Scientists have discovered a new and potent anti-cancer compound in everyday food. The collaborative study led by UCL (University College London) shows that the compound-inositol pentakisphosphate-found in beans, nuts and cereals inhibits a key enzyme (phosphoinositide 3-kinase) involved in tumour... view more (2005-09-16)

Outsmarting cancer - new results from novel enzyme inhibitors
Smart drugs that can break the chain of command between enzymes and the genes involved in cell division and cell death are a new way forward in tackling breast cancer, according to Dr Stephen Johnston, a consultant oncologist from The Royal Marsden Hospital, London, UK. He was speaking at a news... view more (2002-03-19)

Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
Working with human colorectal cancer cells, a University of Minnesota team, led by cancer biologists Zigang Dong and Ann Bode, has found the potential culprit among a network of enzymes that relay signals inside cells to regulate such functions as cell growth, cancer development and programmed cell... view more (2007-08-01)

To evade chemotherapy, some cancer cells mimic stem cells
Anti-cancer treatments often effectively shrink the size of tumors, but some might have an opposite effect, actually expanding the small population of cancer stem cells believed to drive the disease, according to findings presented today in Atlanta, Georgia at the American Association for Cancer... view more (2007-09-20)

Lymph nodes harbor information on whether breast cancer will recur
Breast cancer often spreads through the lymph nodes in the arm pits (so-called axillary lymph nodes), and whether these lymph nodes are tumor-free or contain small metastases is an important factor in the decision of how aggressively to treat a patient.   view more (2005-09-06)

There goes the neighborhood: Vascular niche nurtures brain tumor stem cells
Self-renewing cancer stem cells (CSCs) comprise only a tiny fraction of most brain tumors, but eliminating them is likely to have a profound impact on the ability of a tumor to survive and grow.   view more (2007-01-17)

Antibiotic inhibits cancer gene activity
A little-known antibiotic shows early promise as an anti-cancer agent, inhibiting a gene found at higher-than-normal levels in most human tumors.   view more (2006-10-02)
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