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TAMOXIFEN FOR PREVENTION OF BREAST CANCER - ENCOURAGING RESULTS BUT RISKS STILL UNCLEAR (pp 813, 817)
Early findings from a randomised trial investigating the effectiveness of tamoxifen to prevent breast cancer are reported in this week’s issue of THE LANCET. Although tamoxifen reduced breast cancer incidence by a third compared with women given placebo, the authors of the study caution that it is still too early to fully assess the risk to... view more... (2002-09-11)
New drug achieves pancreatic cancer tumor remission and prevents recurrence
Pancreatic cancer remains one of the deadliest cancers, but researchers may have found a combination therapy to reduce cancer stem cells and stop pancreatic cancer growth. Results will be presented at the American Association for Cancer Research 100th Annual Meeting 2009. view more (2009-04-20)
Metals could forge new cancer drug
Drugs made using unusual metals could form an effective treatment against colon and ovarian cancer, including cancerous cells that have developed immunity to other drugs, according to research at the University of Warwick and the University of Leeds. view more (2009-10-19)
Synthetic molecule causes cancer cells to self-destruct
Scientists have found a way to trick cancer cells into committing suicide. The novel technique potentially offers an effective method of providing personalized anti-cancer therapy. view more (2006-08-28)
PREOPERATIVE RADIOTHERAPY IMPROVES OUTCOME IN RECTAL CANCER (PP 1285, 1291)
Preoperative radiotherapy reduces risk of local recurrence and death from rectal cancer, conclude authors of a systematic overview published in this week's issue of The Lancet. There are different opinions about when it is best to give radiotherapy for rectal cancer. In Scandinavia, the Netherlands, and some other European countries, radiotherapy... view more... (2001-10-17)
Dormant cancer cells rely on cellular self-cannibalization to survive
A single tumor-suppressing gene is a key to understanding, and perhaps killing, dormant ovarian cancer cells that persist after initial treatment only to reawaken years later, researchers at The University of Texas M. D. Anderson Cancer Center report in the December Journal of Clinical Investigation. view more (2009-01-05)
SLU scientists have identified the first gene regulating programmed cell death in plant embryos
A research team at the Swedish University of Agricultural Sciences, SLU, has succeeded in isolating a novel gene that regulates cell death in plant embryos. This is a world first. The team consists of scientists from the Department of Plant Biology and Forest Genetics, headed by Peter Bozhkov and Sara von Arnold. The team has discovered... view more... (2004-06-01)
Low vitamin D levels associated with increased risk of death
Individuals with low levels of vitamin D appear to have a higher risk of death from all causes, according to a report in the August 11/25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. view more (2008-08-12)
Study finds that significant proportion of men told wife's cancer was incurable late or not at all
A study conducted in Sweden found that more than 40 percent of widowers in that country whose wives died from cancer four or five years earlier reported they were either never told that their spouse's cancer was incurable, or they heard this information during the last week of her life. view more (2008-07-09)
Prostate cancer therapy may increase risk of death from heart disease in older men
Androgen deprivation therapy-one of the most common treatments for prostate cancer-may increase the risk of death from heart disease in patients over age 65, according to a new study by researchers at Dana-Farber Cancer Institute, Brigham and Women's Hospital and other institutions. view more (2007-02-26)
Scots and Irish at greater risk of drink-related death, study shows
Alcohol-related deaths in England and Wales are twice as high among people born in Scotland or Ireland compared with the rest of the population, a study has shown. view more (2009-03-19)
Detection of glycoprotein could identify ovarian and uterine cancers with poor prognosis (p 865)
Issue 13 September 2003 Embargoed 0001 h (London time) 12 September 2003. The detection of a specific protein molecule could help oncologists identify uterine and ovarian cancers with poor prognosis and thereby enable better disease management of women with aggressive uterine or ovarian cancer, suggest authors of a study in this week's issue of... view more... (2003-09-10)
Molecular pathway linked to breast cancer recurrence
A study published in the September issue of Cancer Cell provides new evidence for a genetic pathway that is involved in the recurrence of breast cancer and identifies a potential target for development of new anticancer therapeutics. view more (2005-09-20)
Therapeutic peptide frees the protein p73 to kill tumor cells
The protein p53 suppresses tumor development by potently inducing tumor cell death, making it an obvious target for anticancer therapeutics. view more (2007-03-09)
Eating plenty of fruit in childhood may protect against cancer in adulthood
A childhood diet rich in fruit may protect against the development of certain cancers in later life, suggests a long term study of almost 4,000 people in the Journal of Epidemiology and Community Health. The researchers based their findings on a 60 year follow up of a group of people who had completed a week's household food inventory during the... view more... (2003-02-18)
Light therapy could be a new approach to treating patients with pancreatic cancer
Pancreatic cancer is notoriously difficult to treat, largely because of the location of the pancreas close to major arteries and vital organs, and the effects of a poorly functioning pancreas on the rest of the body. It is one of the top 10 leading causes of death from cancer worldwide, and in the UK kills around 6500 people every year. view more (2002-03-11)
Laparoscopy For Colon Cancer Could Offer Long-term Survival Benefit Over Conventional Surgery
A study in this week's issue of THE LANCET suggests that laparoscopy-assisted surgery to treat colon cancer could be more favourable than conventional open surgery, with the potential to reduce operative complications, hospital stay, and increase cancer-related survival in the longer term. Colorectal cancer is the second leading cause of... view more... (2002-06-26)
Penn researchers identify new combination therapy that promotes cancer cell death
Researchers at the University of Pennsylvania School of Medicine identified a combination therapy as a way to sensitize resistant human cancer cells to a treatment currently being tested in clinical trials. view more (2007-07-17)
Cancer Mortality Rates Experience Steady Decline
The number of cancer deaths has declined steadily in the last three decades. Although younger people have experienced the steepest declines, all age groups have shown some improvement, according to a recent report in Cancer Research, a journal of the American Association for Cancer Research. view more (2009-08-14)
Racial disparities decline for cancer in Missouri
Cancer death rates in the United States are highest among African Americans, but a new report shows that in Missouri the disparity in cancer incidence and death between African Americans and whites is declining. view more (2008-09-24)
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