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Cancer Drug Current Events | Cancer Drug News | 10

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Genetic Engineering & Biotechnology News reports on growing role of molecular diagnostics
Novel platform technologies and key advances in genomics are rapidly driving the development of molecular diagnostics, reports Genetic Engineering and Biotechnology News (GEN).   view more (2008-10-06)

Treatments have same target, different responses for lung cancer patients with genetic mutation
The gene mutation that identifies the lung cancer patients most likely to respond to the drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux).   view more (2005-08-17)

A sticky business -- how cancer cells become more 'gloopy' as they die
The viscosity, or 'gloopiness', of different parts of cancer cells increases dramatically when they are blasted with light-activated cancer drugs, according to new images that provide fundamental insights into how cancer cells die, published in Nature Chemistry today (15 March).    view more (2009-03-16)

Hormone drug linked to increased prevalence of male genital disorder (pp 1081, 1102)
Results of a Dutch study in this week’s issue of THE LANCET highlight how a male genital disorder could be more common among boys born to mothers who were prenatally exposed to a synthetic hormone withdrawn in the late 1970s. The drug diethylstilbestrol (DES) was previously prescribed to prevent spontaneous abortion and preterm delivery. DES... view more... (2002-03-27)

Study finds flaws in cancer clinical trials
Cancer research and drug development are yielding more sophisticated candidate therapies, but investigators' methods to test them haven't kept pace, according to researchers at Memorial Sloan-Kettering Cancer Center.   view more (2007-02-02)

1930s drug slows tumor growth
Drugs sometimes have beneficial side effects. A glaucoma treatment causes luscious eyelashes. A blood pressure drug also aids those with a rare genetic disease.   view more (2009-11-09)

Support for chromosomal theory of cancer found in cancers' development of drug resistance
Thirty-six years into the war on cancer, scientists have not only failed to come up with a cure, but most of the newer drugs suffer from the same problems as those available in the pre-war days: serious toxicity, limited effectiveness and eventual resistance.   view more (2007-06-28)

EU Funding Helps Fight Liver Cancer
The fight against liver cancer, one of the leading causes of cancer death worldwide, is being helped by 2.5 million euros from the EU's Framework Programme.   view more (2005-02-22)

Drug treatment likely to be based on biased evidence
Drug treatment is likely to be founded on biased evidence because drug companies tend to publish studies with more favourable results, suggest researchers in this week’s BMJ.   view more (2003-05-28)

"Suicide gene" injection shrinks cancer growth
Injectable "suicide gene" therapy may be a highly effective way of preventing colon cancer from spreading (metastasising), finds research in Gut. Human colon cancer carries a high risk of death because it is often not found in the early stages and readily spreads to the liver, but also the lungs and throughout the abdominal cavity (peritoneum).   view more (2002-02-08)

Brain-boosting pill alleviates post-chemotherapy fogginess
A drug described by some people as a "genius pill" for enhancing cognitive function provided relief to a small group of Rochester breast cancer survivors who were coping with a side effect known as "chemo-brain," according to a University of Rochester Medical Center study.   view more (2007-06-04)

Biodegradable gel being studied as a treatment for esophageal cancer
Gastroenterologists at Rush University Medical Center are studying the safety and efficacy of a new system for delivering chemotherapy for patients with esophageal cancer, a rare, but deadly disease that attacks the throat.   view more (2009-04-16)

Munich Biotech reports additional positive data from MBT- 0206 Phase I trial
Continued Tolerability, Quality of Life Improvement, Stabilization and Regression Seen in Cancer Patients on Extension Past Phase I Clinical Trials Munich, March 25th, 2004 - Munich Biotech AG has announced details of results presented during a recent congress of clinical investigators, reporting on results of Phase I trials of MBT-0206 in cancer... view more... (2004-03-25)

University of Helsinki to coordinate two large EU research projects
The European Union has granted nearly 25 MEUR to two large-scale interdisciplinary research projects coordinated by the University of Helsinki. The project leaders are professor Raimo Tuominen from the UH's Faculty of Pharmacy and Academy professor Kari Alitalo from UH's Molecular and Cancer Biology Laboratory. Both projects are part of the... view more... (2004-08-24)

Animal Study Identifies Promising New Target for Brain Tumor Therapy
A drug that targets the body's immune cells may be effective in treating malignant brain tumors, according to a new study led by researchers at Duke's Preston Robert Tisch Brain Tumor Center. In animal models, the drug re-engaged the body's cancer-damaged immune system.   view more (2007-05-09)

Study implicates protein as a trigger of advanced prostate cancer recurrence
Scientists with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have for the first time implicated a growth-promoting cellular protein as one trigger of the inevitable recurrence of advanced prostate cancer in men who are undergoing drug treatment to shut down their sex hormones, or androgens.   view more (2007-05-09)

Adding cetuximab to chemotherapy reduces advanced lung cancer death risk by 13 percent
Patients with advanced non-small cell lung cancer who are given cetuximab (Erbitux) in addition to chemotherapy are 13% less likely to die than those who receive chemotherapy alone, regardless of which chemotherapy drug cocktail is used, new research finds. They also experience slower disease progression and an increased chance of tumour shrinkage.   view more (2009-09-22)

UCF researcher's nanoparticles could someday lead to end of chemotherapy
Nanoparticles specially engineered by University of Central Florida Assistant Professor J. Manuel Perez and his colleagues could someday target and destroy tumors, sparing patients from toxic, whole-body chemotherapies.   view more (2009-06-17)

Prostate cancer research may be faster with PSA endpoints
A new study from Columbia University Medical Center researchers at NewYork-Presbyterian Hospital/Columbia, who are members of the Southwest Oncology Group (SWOG), suggests that certain changes in prostate-specific antigen (PSA) levels may serve as surrogate endpoints for prostate cancer survival.   view more (2006-04-19)

Allergy drug slows pancreatic tumor growth in preclinical studies
An anti-allergy drug in use for more than 40 years significantly reduced tumor growth in animal models of human pancreatic cancer and also increased the effectiveness of standard chemotherapy.   view more (2006-12-20)
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