Cancer Drug Current Events | Cancer Drug News | 10
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Prostate cancer research may be faster with PSA endpoints
A new study from Columbia University Medical Center researchers at NewYork-Presbyterian Hospital/Columbia, who are members of the Southwest Oncology Group (SWOG), suggests that certain changes in prostate-specific antigen (PSA) levels may serve as surrogate endpoints for prostate cancer survival. view more (2006-04-19)
Allergy drug slows pancreatic tumor growth in preclinical studies
An anti-allergy drug in use for more than 40 years significantly reduced tumor growth in animal models of human pancreatic cancer and also increased the effectiveness of standard chemotherapy. view more (2006-12-20)
OHSU Cancer Institute researchers identify new approach to help control drug resistance in leukemia
Oregon Health & Science University Cancer Institute researchers have found that an experimental drug known as SGX393 is effective against Gleevec-resistant chronic myeloid leukemia (CML). The results of their study will be published the week of March 24th in the Proceedings of the National Academy of Sciences. view more (2008-03-25)
Researchers identify key gene that may be a marker of breast cancer metastasis
Researchers at Fox Chase Cancer Center have identified an important gene involved in the spread of breast cancer that has developed resistance to long-term estrogen deprivation. view more (2007-04-19)
Researchers uncover how prostate cancer cells defy death
New findings about how prostate cancer cells are able to resist hormone treatment and defy death may lead to more effective drug treatments. view more (2006-07-31)
Who gets cancer treatment, and who completes it?
Cancer treatment is now very effective in many cases, yet not all patients with cancer are referred and not all complete their treatment programme. This has puzzled cancer specialists who have wondered if psychological factors might influence their decision and has led to research carried out by Dr Stan Lindsay from the Institute of Psychiatry in... view more... (2002-11-13)
Fruit fly protein acts as decoy to capture tumor growth factors, find Penn researchers
Researchers at the University of Pennsylvania School of Medicine have shown how Argos, a fruit fly protein, acts as a ¡¥decoy' receptor, binding growth factors that promote the progression of cancer. view more (2008-05-29)
Statin plus cancer drug deliver combo punch to brain cancer cells
Building on newly discovered genetic threads in the rich tapestry of biochemical signals that cause cancer, a Johns Hopkins Kimmel Cancer Center team has dramatically killed brain cancer cells by blocking those signals with a statin and an experimental antitumor drug. view more (2007-01-19)
Breast cancer treatment resistance linked to signaling pathway
Activation of the Src signaling pathway may cause resistance to standard medical treatment in some patients with breast cancer, and inhibition of this pathway holds the potential to overcome that resistance, according to data presented here at the American Association for Cancer Research Molecular Diagnostics in Cancer Therapeutic Development... view more... (2008-09-23)
OHSU Cancer Institute finds that drug stimulated immune system in prostate cancer
In a multi-site study, Oregon Health & Science University Cancer Institute researchers have found that a drug called Ipilimumab, also known as MDX-010, works to stimulate the body's own immune system to fight prostate cancer. The drug was found to be effective in study participants with a serious type of prostate cancer - one where the tumor... view more... (2008-06-03)
Tea, turmeric and the fight against cancer
"There has been a marked increase in cancer research in Leicester in recent years. A great deal of the new work that we undertake here now relates to assessment of novel treatments and prevention and much of the funding for this comes from drug trials for pharmaceutical companies. It is extremely rare for universities to take a drug right through... view more... (1999-12-14)
Cholesterol-lowering drugs not associated with reduced colorectal cancer risk
Use of cholesterol reducing drugs is not associated with a reduced risk of colorectal cancer, according to a study in the January 4 issue of the Journal of the National Cancer Institute . view more (2006-01-04)
Light powered platinum more targeted & 80 times more powerful than similar cancer treatments
Researchers from the Universities of Warwick, Edinburgh, Dundee and the Czech Republic's Institute of Biophysics have discovered a new light-activated platinum-based compound that is up to 80 times more powerful than other platinum-based anti-cancer drugs and which can use "light activation" to kill cancer cells in much more targeted way... view more... (2007-12-26)
Research Shows Prescribers Miss Possibly Dangerous Drug Interactions
Research led by The University of Arizona College of Pharmacy has found that medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions. view more (2009-07-14)
Light activated anticancer drug targeted to DNA using cisplatin like sub-units
One of the most effective chemotherapy drugs against cancer is cisplatin because it attaches to cancer DNA and disrupts repair. view more (2006-03-27)
Weekly dose of osteoporosis drug prevents bone loss after breast cancer treatment
Breast cancer survivors who took a weekly dose of risedronate, sold as Actonel, lost significantly less bone than those who did not take the drug. view more (2007-09-19)
Tulane pioneers novel ovarian cancer treatment
The Tulane University Section of Hematology and Medical Oncology is investigating a novel treatment for ovarian cancer by using intravenous Ontak to deplete harmful cells that inhibit the body's natural immune response to fight cancer. Ovarian cancer is the fifth leading cancer killer of women in the United States. view more (2005-07-18)
Would you like fries with that?
Exploiting interactions between food and drugs could dramatically lower the rapidly rising costs of several anticancer drugs, and perhaps many other medications, two cancer-pharmacology specialists suggest in a commentary in the July 16, 2007, issue of the Journal of Clinical Oncology. view more (2007-07-17)
First antisense drug provides benefit to subset of chronic lymphocytic leukemia patients
The first "antisense" drug to be tested in chronic lymphocytic leukemia (CLL) shows benefit in a phase III clinical trial for a specific subset of patients-those who are still sensitive to a chemotherapy drug often used to treat this cancer. view more (2007-02-15)
Breast Cancer Drug Shows Promise for Treating, Preventing Progestin-Dependent Tumors
Recent studies suggest that human breast cancer risk is increased by outside exposure to the hormone progestin, such as during hormone replacement therapy. Now, a University of Missouri study suggests that PRIMA-1, a small molecule drug that targets the most common mutated gene, p53, in human cancer cells, has potential as a novel chemotherapeutic... view more... (2009-01-29)
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