Cancer Drug Current Events | Cancer Drug News | 2
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Novel mechanism of taxane resistance
Research Associate Chih-Jian Lih and others working in the laboratory of Dr. Stanley N. Cohen at Stanford University have pinpointed a gene that affects human cancer cells' sensitivity to chemotherapy-an important finding in the effort to increase the effectiveness of chemotherapy. view more (2006-07-17)
FDA approved leukemia drugs shows promise in ovarian cancer cells
The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA's Jonsson Comprehensive Cancer Center found. view more (2009-11-10)
Pros, cons of drug proven to prevent prostate cancer should be considered, researchers recommend
Findings by UT Southwestern Medical Center researchers encourage men to weigh both the potential benefits and side effects of the drug finasteride before taking it to prevent prostate cancer. view more (2008-01-21)
Pancreatic cancer: Researchers find drug that reverses resistance to chemotherapy
For the first time researchers have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreatic cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease. view more (2009-09-24)
Shrinkage of prostate led to overestimation of cancer risk in trial
Reanalysis of data from the first long-term randomized trial of a chemopreventive agent for prostate cancer shows that the excess prevalence of high-grade prostate cancer in the drug-treated group may be attributable to shrinkage of the prostate at the time of biopsy. view more (2007-09-13)
Gene patenting -- steep cost for health care and patients
The drug trastuzumab (Herceptin) is used to treat HER2-positive breast cancer (a type of breast cancer that overexpresses the HER2 gene and accounts for about 25% of all breast cancers). view more (2007-05-08)
Cancer cells lose drug resistance following electrical stimulation in vitro
Drug-resistant tumour cells lose their drug resistance when exposed to low intensity, low frequency electric pulses for three days. view more (2006-03-17)
Researchers study effects of Aricept in pediatric brain cancer survivors
A pediatric oncologist at Brenner Children's Hospital is evaluating whether a drug typically used to treat Alzheimer's patients will help brain cancer survivors avoid the learning and memory problems that are common after radiation therapy. view more (2006-11-06)
Metals could forge new cancer drug
Drugs made using unusual metals could form an effective treatment against colon and ovarian cancer, including cancerous cells that have developed immunity to other drugs, according to research at the University of Warwick and the University of Leeds. view more (2009-10-19)
Morphochem And Fox Chase Cancer Center Enter Into Collaboration To Develop Novel Treatments For Cancer
Morphochem AG, a leader in chemical genomics, and Fox Chase Cancer Center (Philadelphia, US), a comprehensive cancer center, have entered into a research collaboration that will leverage the strengths of both organizations to develop new treatments for cancer. The collaboration is wide ranging and provides for multiple research projects under the... view more... (2002-10-16)
Identifying cancer genes - will it really lead to better treatment?
Copenhagen, Denmark: A systematic trawl through the human genome looking for the abnormalities that drive cancer is already producing promising results, a scientist told ECCO 12 - The European Cancer Conference in Copenhagen today (Tuesday 23 September). Dr. Michael Stratton, Director of the Cancer Genome Project at the Wellcome Trust Sanger... view more... (2003-09-21)
UNC study questions FDA genetic-screening guidelines for cancer drug
Not everyone needs a genetic test before taking the cancer drug irinotecan, and the U.S. Food and Drug Administration should modify its prescription guidelines to say so, according to researchers at the University of North Carolina at Chapel Hill. view more (2007-08-29)
Ovarian cancer responds to aspirin derivative with chemo
A new study using ovarian cancer cell lines shows promise in treating the deadly disease by combining the chemotherapy drug cisplatin with an aspirin-like compound to make recurrent cancer cells less resistant to the chemotherapy. view more (2006-02-16)
Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual... view more... (2007-06-18)
Analysis shows combining sorafenib with carboplatin/paclitaxel adds no benefit in lung cancer
A clinical trial evaluating the benefit of adding the drug sorafenib to the combination of carboplatin/paclitaxel chemotherapy for lung cancer patients has been stopped based on results from an interim analysis, after an independent data monitoring committee concluded that the study would not meet its primary endpoint of improved overall survival. view more (2008-04-28)
HtrA1 and resistance to chemotherapy in ovarian and gastric cancers
While many cancer patients initially have a favorable response to chemotherapy for the treatment of solid tumors, resistance to treatment often develops. view more (2006-06-09)
New drugs boost for asbestos-related lung cancer sufferers
Clinical trials of a new anticancer drug combination carried out by researchers at Newcastle University show that it has potential to almost double the life expectancy of sufferers of Mesothelioma - a form of lung cancer which affects around 1,700 people in the UK every year - according to a report published in the Journal of Clinical Oncology.... view more... (2002-08-12)
Structure of key cancer drug target identified
Researchers from Monash's Department of Biochemistry and Molecular Biology have determined the structure of the protein JAK2 kinase, a discovery with huge implications for the design and development of new cancer drugs. view more (2005-10-26)
Hormone inhibitor promising for hard-to-treat prostate cancer
For prostate cancer patients whose tumors have continued to grow despite medical or surgical castration, a new drug candidate that inhibits production of male hormones anywhere in the body is showing promise in early trials. view more (2007-07-09)
Molecular fingerprint of breast-cancer drug resistance can predict response to treatment
A way of predicting which patients will respond well to treatment with a common chemotherapy drug used in breast cancer was unveiled at the European Cancer Conference (ECCO 14) today (Monday 24 September). view more (2007-09-25)
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