Cancer Drug Current Events | Cancer Drug News | 8
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US researchers show cottonseed drug is cancer treatment booster - patient trials now planned
New research has opened up the prospect that gossypol - a drug refined from cottonseed oil and previously tried and abandoned as a male contraceptive - could boost the effectiveness of treatment for prostate tumours and possibly other common cancers as well. view more (2004-09-29)
Duke develops nano-scale drug delivery for chemotherapy
Going smaller could bring better results, especially when it comes to cancer-fighting drugs. view more (2009-11-02)
UCSB researchers develop drug delivery system using nanoparticles and lasers
Researchers at UC Santa Barbara have developed a new way to deliver drugs into cancer cells by exposing them briefly to a non-harmful laser. view more (2009-09-10)
Low-dose chemotherapy plus antiangiogenesis drug has activity in advanced breast cancer
Chemotherapy given in low, frequent doses - a novel strategy called "metronomic" delivery - achieved partial shrinkage of disease in some advanced breast cancer patients when given concurrently with an angiogenesis inhibitor. view more (2005-12-09)
New cancer drug test promises safer and more effective clinical trials
A group of scientists from Hamburg may have taken a big step towards more effective cancer drug development. view more (2009-09-23)
Drug slows prostate tumor growth by keeping vitamin A active
A novel compound that blocks the breakdown of retinoic acid, derived from vitamin A, is a surprisingly effective and "promiscuous" agent in treating animal models of human prostate cancer, say investigators from the University of Maryland, Baltimore (UMB). view more (2007-11-07)
Variation of normal protein could be key to resistance to common cancer drug
Researchers at the Moores Cancer Center at the University of California, San Diego (UC SD) in La Jolla have found evidence explaining why a common chemotherapy drug, cisplatin, may not always work for every cancer patient. They have shown that when a variant version of a key protein that normally causes cell death is active, patients may be... view more... (2008-08-28)
Stem cells as cancer therapy
It is widely hoped that neural stem cells will eventually be useful for replacing nerves damaged by degenerative diseases like Alzheimer disease and multiple sclerosis. But there may also be another use for such stem cells-delivering anti-cancer drugs to cancer cells. view more (2006-12-26)
Not all 'drug-related deaths' are 'drug-related'
UK estimates of 'drug-related deaths' (DRDs) include mortalities of drug abusers and non-drug abusers. So these figures may not be the best way of monitoring the performance of Drug and Alcohol Action Teams. view more (2007-08-09)
Diabetes drug shows promise for preventing brain injury from radiation therapy
Researchers at Wake Forest University School of Medicine are the first to report that in animal studies, a common diabetes drug prevents the memory and learning problems that cancer patients often experience after whole-brain radiation treatments. view more (2007-01-11)
Cancer drug extends cognitive function in patients with brain metastases
he drug Xcytrin®, based on a molecule developed by chemists at The University of Texas at Austin, shows significant promise in prolonging cognitive function in patients with non-small cell lung cancer that has metastasized to the brain. view more (2006-06-06)
New type of drug shows promise in attacking melanoma in an innovative way
An experimental drug that attacks cancer in an entirely new way has shown promise in treating advanced melanoma, delaying progression of the disease and prolonging the lives of patients. view more (2007-09-27)
Gene signature may predict patient response to therapy for gastrointestinal stromal tumors
Researchers at Fox Chase Cancer Center uncovered a genetic pattern that may help predict how gastrointestinal stromal tumor (GIST) patients respond to the targeted therapy imatinib mesylate (Gleevec). view more (2009-05-15)
Drug that targets vasculature growth attacks aggressive thyroid cancer
A medication that helps stop the growth of new blood vessels has produced dramatic benefits for some patients with aggressive thyroid cancer, research from Mayo Clinic indicates. view more (2009-05-15)
Mouse tests predict drug response in relapsing pancreatic cancer patients
By slicing up bits of patient tumors and grafting them into mice, Johns Hopkins Kimmel Cancer Center specialists have figured out how to accurately "test drive" chemotherapy drugs to learn in advance which drug treatments offer each individual pancreatic cancer patient the best therapeutic journey. view more (2006-10-12)
Cellular molecule spurs growth of prostate cancer
University of North Carolina at Chapel Hill scientists have identified a molecule that stimulates the aggressive growth of prostate cancer. view more (2005-11-29)
Enzyme inhibitor takes an unexpected approach toward blocking cancer-promoting protein
Scientists at Fox Chase Cancer Center have discovered a unique method of attack that may be used to inhibit signaling enzymes called kinases, which often have a role in sustaining drug-resistant cancerous cells. They have confirmed that IPA-3, a small molecular inhibitor of a kinase called PAK1, targets the enzyme's regulatory domain, mimicking... view more... (2009-09-08)
Why cisplatin kills breast cancer cells when other drugs fail
The cancerous cells of some individuals with breast cancer lack expression of two cell surface proteins, the estrogen and progesterone receptors, and do not express increased amounts of HER2. view more (2007-04-20)
Stealth particles to target tumors
Stealth nano particles may some day target tumor cells and deliver medication to specific body locations, according to Penn State chemical engineers. view more (2005-09-01)
Anti-tumor effects are enhanced by inhibiting 2 pathways rather than 1
Two independent research groups have found that simultaneous inhibition of two signaling pathways resulted in substantially enhanced antitumor effects in mouse models of prostate and breast cancer. In an accompany commentary, Steven Grant, at Virginia Commonwealth University Health Science Center, Richmond, discusses the clinical importance of... view more... (2008-08-22)
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